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Elevated folic acid results in contrasting cancer cell line growth with implications for mandatory folic acid fortification

Yates Z, Lucock M, Veysey M, Choi JH

PURPOSE: The initiation of mandatory folic acid fortification using pteroylmonoglutamic acid (PteGlu) has reduced the rate of congenital malformations. However, it also appears to be responsible for several adverse effects,...
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Postprandial hypoglycemic effects of mulberry twig and root bark in vivo and in vitro

Park SY, Jin BR, Lee YR, Kim YJ, Park JB, Jeon YH, Choi SW, Kwon O

PURPOSE: Our previous study demonstrated the hypoglycemic effects of mulberry (Morus alba L.) leaf and the underlying mechanisms. Here we explored the potency of mulberry twigs (TW) and root barks...
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Chemopreventive effect of alpha-viniferin in azoxymethane-induced mouse colorectal tumor and Caco-2 cells

Kwak DH, Shin SK, Youm SY, Kim TW, Kim Y, Ahn B

alpha-Viniferin (AVF), a trimer of resveratrol, is known to have an anti-inflammatory effect via inhibition of cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS). It has been reported that up-regulated...
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Degradation of the Transcription Factors NF-kappaB, STAT3, and STAT5 Is Involved in Entamoeba histolytica-Induced Cell Death in Caco-2 Colonic Epithelial Cells

Kim KA, Min A, Lee YA, Shin MH

Entamoeba histolytica is a tissue-invasive protozoan parasite causing dysentery in humans. During infection of colonic tissues, amoebic trophozoites are able to kill host cells via apoptosis or necrosis, both of...
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TNF-alpha Downregulates E-cadherin and Sensitizes Response to gamma-irradiation in Caco-2 Cells

Yi JY, Jung YJ, Choi SS, Chung E

  • KMID: 2128578
  • Cancer Res Treat.
  • 2009 Sep;41(3):164-170.
PURPOSE: The purpose of the present study was to assess the biological effects of TNF-alpha in Caco-2 well-differentiated colon adenocarcinoma cells and to determine radiation sensitivity in order to develop...
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In vitro Model System of Transepithelial Migration of Neutrophil by Helicobacter pylori

Jung HC, Kim JG, Kim JM, Song IS, Park SM

  • KMID: 772517
  • Korean J Gastroenterol.
  • 2003 Jul;42(1):20-26.
BACKGROUND/AIMS: Migration of neutrophil across the intestinal epithelium is a structural hallmark of active intestinal diseases. One of the characteristic histologic features of Helicobacter pylori (H. pylori) infection is...
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