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Gastric CD56-negative Extranodal Natural Killer/T-cell Lymphoma: A Case Report

Chung J, Jee SR, Choi E, Yu SJ, Yoon JS, Lee HS, Lee SH, Park SJ, Park HY

Extranodal natural killer (NK)/T-cell lymphoma, nasal type (ENKTCL-NT) is the most common subtype of Epstein-Barr virus-associated NK/T-cell lymphomas. ENKTCL-NT occurs infrequently in the gastrointestinal tract. In particular, reports of ENKTCL-on...
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Gamma-ray irradiation modulates PGRMC1 expression and the number of CD56+ and FoxP3+ cells in the tumor microenvironment of endometrial endometrioid adenocarcinoma

Zinovkin DA, Lyzikova YA, Nadyrov EA, Petrenyov DR, Yuzugulen J, Pranjol MZI

Purpose: Although the conventional gamma ray brachytherapy has been successful in treating endometrioid endometrial adenocarcinoma (EC), the molecular and cellular mechanisms of this anti-tumorigenic response remain unclear. Therefore, we investigated...
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The Usefulness of Immunocytochemistry of CD56 in Determining Malignancy from Indeterminate Thyroid Fine-Needle Aspiration Cytology

Cha H, Pyo JY, Hong SW

BACKGROUND: Fine-needle aspiration cytology serves as a safe, economical tool in evaluating thyroid nodules. However, about 30% of the samples are categorized as indeterminate. Hence, many immunocytochemistry markers have been...
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Cytotoxic activity and subset populations of peripheral blood natural killer cells in patients with chronic pain

Yoon JJ, Song JA, Park SY, Choi JI

BACKGROUND: Chronic pain reportedly exerts complex effects on immune function. Natural killer (NK) cells are lymphocytes that play a critical role in cellular and innate immunity. This study examined changes...
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The Intraoperative Immunohistochemical Staining of CD56 and CK19 Improves Surgical Decision for Thyroid Follicular Lesions

Pyo JY, Choi SE, Shin E, Koo J, Hong S

BACKGROUND: When differential diagnosis is difficult in thyroid follicular lesions with overlapping histological features, the immunohistochemical staining can help confirm the diagnosis. We aimed to evaluate the effectiveness of rapid...
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Extremely Well-Differentiated Papillary Thyroid Carcinoma Resembling Adenomatous Hyperplasia Can Metastasize to the Skull: A Case Report

Pyo JY, Kim J, Choi SE, Shin E, Yang SW, Park CS, Kim SM, Hong S

We describe herein histologic, immunohistochemical, and molecular findings and clinical manifestations of a rare case of an extremely well differentiated papillary thyroid carcinoma (EWD-PTC). Similarly, it is also difficult to...
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A Case of Blastic Plasmacytoid Dendritic Cell Neoplasm in Child

Choi JH, Kim BS, Sohng SH, Shin DH, Choi JS

  • KMID: 2246460
  • Korean J Dermatol.
  • 2013 Dec;51(12):970-974.
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and highly aggressive hematopoietic malignancy which is derived from the precursors of plasmacytoid dendritic cells and is more infrequent in children...
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CD 4+/CD56+ Hematodermic Neoplasm in Infancy: Case Report

Suhng EA, Cheong SH, Choi HY, Myung KB, Choi YW

  • KMID: 2247532
  • Korean J Dermatol.
  • 2011 Nov;49(11):1017-1020.
CD4+/CD56+ hematodermic neoplasm is a rare and aggressive lesion that affects many organs, and skin involvement is highly characteristic. It is also termed blastic natural killer cell lymphoma in the...
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CD56 and High Molecular Weight Cytokeratin as Diagnostic Markers of Papillary Thyroid Carcinoma

Shin MK, Kim JW, Ju YS

BACKGROUND: The incidence of papillary thyroid carcinoma (PTC) has been increasing recently and a precise diagnosis is essential for optimal treatment. Ancillary immunohistochemical stains are important for diagnosing some difficult...
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Relapsed extranodal NK/T-cell lymphoma in the mandible, Nasal Type: a case report and review of the literatures

Park YW, Park YT, Choi KH, Kim SG

Extranodal NK/T-cell lymphoma (NTCL), nasal type is rare and highly fatal malignant neoplasm. Early diagnosis and establishing treatment plan are very difficult. Furthermore, NTCL in the mandible is an extremely...
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Increased Peripheral NK Cell Fraction and Their Cytolytic activity in Patients with History of Recurrent Spontaneous Abortion

Choi JY, Hwang SJ, Han AR, Yoo JH, Park DW, Park CW, Kim HO, Cha SH, Kim JY, Song IO, Koong MK, Kang IS, Yang KM

  • KMID: 2036677
  • Korean J Reprod Med.
  • 2010 Jun;37(2):115-124.
OBJECTIVE: To testify whether the increased peripheral blood natural killer (pbNK) cells fraction and their cytolytic activity could coincide with patient's history of recurrent spontaneous abortion (RSA) and to evaluate...
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CD4-/CD56+/CD123+ Hematodermic Neoplasm Showing Early Liver Metastasis

Choi KW, Lee KY, Lee YK, Ku BS, Kim HS, Kim YH, Kim KH

Hematodermic neoplasm (HN) is a clinically aggressive neoplasm with a high incidence of cutaneous involvement and a risk of leukemic dissemination. In the recent WHO-EORTC classification, the term blastic natural...
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T-cell Large Granular Lymphocytic Leukemia: A Case Report

Song SH, Chung SM, Hwang DW, Choi JY, Yoo KD, Hong HS, Ahn YW, Roh YW, Lee JS, Park BB, Choi JH, Kim IS, Lee WS, Lee YY

T cell large granular lymphocytic leukemia (T-LGL leukemia) is defined as a clonal proliferative disorder of CD3+ cytotoxic T cells. T-LGL leukemia usually expresses CD3+, CD4-, CD8+, CD16+, CD56- and...
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Expression of Decidual Natural Killer (NK) Cells in Recurrent Abortion Patients with Increased Peripheral NK Cells

Lee HJ, Kim SH, Yang KM, Park DW, Park CW, Hong SR, Cho DH, Song IO, Koong MK, Kang IS

  • KMID: 1473570
  • Korean J Reprod Med.
  • 2009 Sep;36(3):199-208.
OBJECTIVES: The purpose of this study was to compare the decidual NK cell populations between increased pre-conceptional peripheral NK cell population and normal pre-conceptional peripheral NK cell population in women...
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Expression of Decidual Natural Killer (NK) Cells in Women of Recurrent Abortion with Increased Peripheral NK Cells

Yeon MJ, Yang KM, Park CW, Song IO, Kang IS, Hong SR, Cho DH, Cho YK

  • KMID: 1986920
  • Korean J Reprod Med.
  • 2008 Jun;35(2):119-129.
OBJECTIVE: The purpose of this study was to quantify decidual CD56+ and CD16+ NK cell subtype population and to evaluate the correlation between decidual NK cell expression and peripheral CD56+...
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A Case of Small Cell Carcinoma of Unknown Primary

Cho SY, Kang SY, Lee JJ, Lim SJ, Lee WI

Small cell carcinoma with unknown primary (SCUP) is an uncommon cancer. Histologically, SCUP has been included with extrapulmonary small cell carcinoma (EPSCC) that is defined as a biopsy proven small...
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CD56/CD16 Expression on Mononuclear Cells and Concentration of Serum TNF-alpha in Recurrent Spontaneous Abortion

Kim HR, Park AJ, Lee MK, Cho DH

BACKGROUND: Recurrent spontaneous abortion (RSA) is defined as the occurrence of three or more consecutive spontaneous abortion before 20 gestational weeks. But, 40-50% of RSA still remain "unex-plained". Cytokines seem...
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CD56+ T-cell Prolymphocytic Leukemia Showing a High Expression Level of TCL1 Oncogene: A Case Report with a Review of the Literature

Yun HK, Shin MG, Kim HJ, Kim HR, Park JY, Cho D, Kee SJ, Kim YH, Shin JH, Suh SP, Ryang DW

T-cell prolymphocytic leukemia (T-PLL) is a rare mature post-thymic T-cell malignancy with infiltration to the blood, bone marrow, lymph node, liver, spleen and skin; this disease has a poor prognosis...
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Phenotypic Characteristics of CD8(bright) T Cells in Behcet's Uveitis

Ahn JK, Yu HG, Kim YJ, Yu YS, Chung H

  • KMID: 1310344
  • J Korean Ophthalmol Soc.
  • 2005 Jul;46(7):1210-1216.
PURPOSE: To determine the phenotypic characteristics of peripheral CD8(bright) T cells. METHODS: Forty patients with Behcet's disease (BD) with uveitis (active: 20; inactive: 20) and 20 healthy controls were recruited...
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Human Activated Lymphocyte Treated with Anti-CD3, CD16, CD56 Monoclonal Antibody and IL-2

Hong SM, Lee DW, Kang JG, Kim HS, Cho SH

BACKGROUND: Throughtout the last three decades, the therapy of leukemias and lymphoma has set the stage for curative cancer therapy in systemic malignant disease. This was the result of an...
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