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Attenuation of airway inflammation by simvastatin and the implications for asthma treatment: is the jury still out?

Liu JN, Suh DH, Yang EM, Lee SI, Park HS, Shin YS

Although some studies have explained the immunomodulatory effects of statins, the exact mechanisms and the therapeutic significance of these molecules remain to be elucidated. This study not only evaluated the...
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Prevention of chronic graft-versus-host disease by stimulation with glucocorticoid-induced TNF receptor

Kim J, Choi WS, Kim HJ, Kwon B

  • KMID: 1105281
  • Exp Mol Med.
  • 2006 Feb;38(1):94-99.
GITR (glucocorticoid-induced TNF receptor) is a recently identified member of the TNF receptor superfamily. The receptor is preferentially expressed on CD4+CD25+ regulatory T cells and GITR signals break the suppressive...
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