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Genetic controls of Th17 cell differentiation and plasticity

Dong C

CD4+ T lymphocytes play a major role in regulation of adaptive immunity. Upon activation, naive T cells differentiate into different functional subsets. In addition to the classical Th1 and Th2...
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Analyses of the TCR repertoire of MHC class II-restricted innate CD4+ T cells

Kang BH, Min HS, Lee YJ, Choi B, Kim EJ, Lee J, Kim JR, Cho KH, Kim TJ, Jung KC, Park SH

Analysis of the T-cell receptor (TCR) repertoire of innate CD4+ T cells selected by major histocompatibility complex (MHC) class II-dependent thymocyte-thymocyte (T-T) interaction (T-T CD4+ T cells) is essential for...
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Constitutive expression of 4-1BB on T cells enhances CD4+ T cell responses

Kim J, Choi SP, La S, Seo JS, Kim KK, Nam SH, Kwon B

  • KMID: 1119332
  • Exp Mol Med.
  • 2003 Dec;35(6):509-517.
4-1BB, a transmembrane molecule, member of the tumor necrosis factor receptor superfamily, is an important costimulatory molecule in the immune response, plays a key role in the clonal expansion and...
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