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A Double-Blind, Split-Face, Randomized Study on the Effects and Safety of Intradermal Injection of Botulinum Toxin A (Incobotulinum Toxin A) in the Cheek

Shin DM, Lee J, Noh H, Jang D, Oh SJ, Park JH, Lee JH

Background: Intradermal injection of botulinum toxin A (BTXA) is used for cosmetic purposes without strong evidence for clinical use, as opposed to intramuscular injection. Objective: To evaluate the efficacy and safety...
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The role of botulinum toxin type A related axon transport in neuropathic pain induced by chronic constriction injury

Bu H, Jiao P, Fan X, Gao Y, Zhang L, Guo H

Background: The mechanism of peripheral axon transport in neuropathic pain is still unclear. Chemokine ligand 13 (CXCL13) and its receptor (C-X-C chemokine receptor type 5, CXCR5) as well as GABA...
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Binocular Visual Rehabilitation in Paralytic Strabismus by Botulinum A Toxin Chemodenervation

Kim M, Lew H

Purpose: To investigate the effect of botulinum A toxin (BTXA) chemodenervation in paralytic strabismus patients without surgical correction. Methods: A retrospective chart review of 51 patients who were diagnosed as paralytic...
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The Influence of Pharyngeal Strength on the Outcome of Botulinum Toxin Treatment for Difficulty in Relaxation of the Upper Esophageal Sphincter

Yim DI, Seo M, Hwang SJ, Lee HJ, Park JW

Objective: Botulinum toxin was used to treat patients with difficulty in relaxation of the upper esophageal sphincter (UES), but the treatment did not always yield good results. We, therefore, attempted...
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Treatment Results of Vocal Process Granuloma: Intubation Versus Contact Granuloma

Jeong JU, Oh JH, Kim S, Kim DY, Woo JH

Background and Objectives Vocal process granulomas (VPGs) are benign lesions of the larynx, typically contact granulomas (CG) and intubation granulomas (IG). The two diseases are known to have different clinical...
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Upper Extremity Deep Vein Thrombosis After Botulinum Toxin Injection: A Case Report

Lim N, Lee GS, Won KH, Kang JS, Lee SH, Kang EY, Lee HK, Cho YK

Botulinum toxin (BoNT) injection is widely used to improve spasticity. However, after the treatment, the patient may experience pain, inflammation, swelling and redness at the injection site. In this case,...
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Combination Treatment of Intra/Perilesional Botulinum Toxin-A Injection and Ablative Fractional Laser for Better Clinical Outcomes of Hypertrophic Fibrotic Thyroidectomy Scars Following Fractional Ablative Laser Resurfacing

Byun HJ, Park JH, Lee JH

Background: Recent reports have shown that intralesional botulinum toxin type-A (BTX-A) works on scar cosmesis. Objective: To evaluate the clinical efficacy of combination treatment of laser and BTX-A injection and compare...
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Adjuvant Role of Botulinum Toxin A in the Management of Wounds Accompanied by Parotid Gland or Duct Injuries

Jeong Y, Lee SY, Sung KY

Background: Parotid gland or duct injuries may occur after facial trauma or surgical procedures around the parotid gland. Such injuries often cause saliva to leak into the wound, and as...
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A Case of Severe Dysphagia after Aesthetic Two-Jaw Surgery

Im YH, Son SA, Park SJ, Park YH

This study reports a case who presented with swallowing difficulty after orthognathic surgery. A female patient, who had undergone orthognathic surgery for esthetic purpose, presented with dysphagia. Administration of botulinum...
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Frontiers in the Clinical Applications of Botulinum Toxin A as Treatment for Neurogenic Lower Urinary Tract Dysfunction

Jiang YH, Chen SF, Kuo HC

Patients with neurogenic lower urinary tract dysfunction (NLUTD) experience urinary incontinence with or without difficult urination, which might promote recurrent urinary tract infection (UTI) and exacerbate upper urinary tract function....
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Accuracy of Ultrasound-Guided and Non-guided Botulinum Toxin Injection Into Neck Muscles Involved in Cervical Dystonia: A Cadaveric Study

Ko YD, Yun SI, Ryoo D, Chung ME, Park J

Objective To compare the accuracy of ultrasound-guided and non-guided botulinum toxin injections into the neck muscles involved in cervical dystonia. Methods Two physicians examined six muscles (sternocleidomastoid, upper trapezius, levator scapulae,...
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Dynamic smile reanimation in facial nerve palsy

Santha KK, Joseph S, Latheef S, Narayanan , Nair SM, Babu B, Sivadasan , Shet SM, Pydi RV, Pati A, Samantaray SA

Objectives: Long-term facial paralysis results in degeneration of the distal nerve segment and atrophy of the supplied muscles. Options for these patients include free muscle transfer, temporalis myoplasty, and botulinum...
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Intravesical Loss of OnabotulinumtoxinA During Endoscopic Intradetrusor Injection - A Multicenter Experience

Šámal V, Krhut J, Paldus V, Műllerová , Mečl J

Purpose: To evaluate intravesical loss of onabolunumtoxinA (onaBTA) during endoscopic injection into the bladder wall for treatment of neurogenic detrusor overactivity (NDO). The intraluminal loss of onaBTA cannot be determined...
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Clinical application of intravesical botulinum toxin type A for overactive bladder and interstitial cystitis

Chen JL, Kuo HC

After decades of clinical and basic science research, the clinical application of botulinum toxin A (Botox) in urology has been extended to neurogenic detrusor overactivity (NDO), idiopathic detrusor overactivity, refractory...
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Safe Needle Insertion Locations for Motor Point Injection of the Triceps Brachii Muscle: A Pilot Cadaveric and Ultrasonography Study

Koo HJ, Park HJ, Park GY, Han Y, Sohn D, Im S

OBJECTIVE: To determine the location of the motor endplate zones (MoEPs) for the three heads of the triceps brachii muscles during cadaveric dissection and estimate the safe injection zone using...
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Validity of bispectral index monitoring during deep sedation in children with spastic cerebral palsy undergoing injection of botulinum toxin

Jung SM, Lee E, Park SJ

BACKGROUND: This prospective study aimed to determine whether the bispectral index (BIS) is a valid objective tool for differentiating adequate from inadequate deep sedation in spontaneously breathing children with cerebral...
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Comparison of Safety and Efficacy of Botox and Neuronox in the Management of Benign Essential Blepharospasm: A Split-face Study

Sane S, Ali MJ, Naik MN

PURPOSE: To compare the efficacy and safety of Botox and Neuronox in the management of benign essential blepharospasm (BEB). METHODS: We performed a triple-masked, randomized control study to compare Botox and...
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Assessment of Anticholinergic Use After Fading of BTX-A Effects in Refractory Idiopathic Overactive Bladder: A Prospective Blinded Randomized Trial

Elbaset MA, Taha DE, El-Hefnawy AS, Zahran MH, Shokeir AA

PURPOSE: To evaluate the efficacy and safety of re-treatment with anticholinergics on refractory idiopathic overactive bladder (OAB) previously treated with intravesical botulinum neurotoxin type A (BTX-A) injections. METHODS: One hundred patients...
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Improvement of Lingual Dystonia Following Cerebellar Infarction through Botulinum Toxin Injection: a Case Report

Bang MH, Kim HS

Lingual dystonia is a rare type of dystonia, the main symptom of which varies from intermittent to sustained tongue fixation. Several studies have suggested that the cerebellum may be implicated...
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Botulinum A Toxin Injection as an Adjuvant Wintering Therapy in Patients with Raynaud's Syndrome

Cho KS, Yoon JS, Ahn HC

PURPOSE: Patients with secondary Raynaud's syndrome experience severe pain and even ulceration of the fingertips, particularly during the winter season. The aim of this retrospective review was to evaluate whether...
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