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Xanthogranulomatous Osteomyelitis Presenting as a Subacute Infectious Condition in the Fibula of a Young Female

Ju SG, Yoon YS, Cha JG, Chin S

Xanthogranulomatous osteomyelitis is a rare, chronic inflammatory disease characterized by infiltrating lipidized histiocytes, lymphocytes, and plasma cells. Xanthogranulomatous osteomyelitis commonly presents as a mass-like lesion on imaging and may be...
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Iris Koreana NAKAI Inhibits Osteoclast Formation via p38-Mediated Nuclear Factor of Activated T Cells 1 Signaling Pathway

Lee HY, Jung JE, Yim M

Background: Iris Koreana NAKAI (IKN) is a flowering perennial plant that belongs to the Iridaceae family. In this study, we aimed to demonstrate the effects of IKN on osteoclast differentiation...
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Newly diagnosed metastatic pulmonary calcification in a kidney transplantation recipient: a case report

Youn S, Yang CW, Chung BH, Ko EJ

Metastatic pulmonary calcification (MPC) is defined as calcium deposition in lung tissues. It is commonly seen in end-stage renal disease patients. However, MPC occurring in kidney transplant recipients (KTRs) is...
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Preliminary Screening Method for Low Bone Mineral Density Using a Self-Reported Questionnaire among Peri- and Postmenopausal Women

Yano Y, Iwata E, Sada T, Ueno Y, Hyakuda Y, Kawasaki S, Okuda A, Shigematsu H, Uematsu K, Yajima H, Tanaka Y

Study Design: Retrospective cohort study. Purpose: We propose a method for screening for low bone mineral density (BMD) among perimenopausal and postmenopausal women using a self-reported questionnaire. Overview of Literature: Osteoporosis is...
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Metabolic Bone Diseases and New Drug Developments

Natesan V, Kim SJ

Metabolic bone diseases are serious health issues worldwide, since several million individuals over the age of 50 are at risk of bone damage and should be worried about their bone...
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Bone Mineral Density Screening Interval and Transition to Osteoporosis in Asian Women

Park H, Yang H, Heo J, Jang HW, Chung JH, Kim TH, Min YK, Kim SW

Background: Bone mineral density (BMD) testing is indicated for women aged 65 years, but screening strategies for osteoporosis are controversial. Currently, there is no study focusing on the BMD testing...
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Interplay of Vitamin D and CYP3A4 Polymorphisms in Endocrine Disorders and Cancer

Kasarla SS, Garikapati V, Kumar Y, Dodoala S

Vitamin D has received considerable optimistic attention as a potentially important factor in many pathological states over the past few decades. However, the proportion of the active form of vitamin...
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Association between Bone Mineral Density and Coronary Atherosclerotic Plaque According to Plaque Composition: Registry for the Women Health Cohort for Bone, Breast, and Coronary Artery Disease Study

Kim KM, Yoon YE, Yun BL, Suh JW

Background: Although biological links are unclear, low bone density and atherosclerosis are inversely associated. This study evaluated the association between bone mineral density (BMD) and coronary computed tomographic angiography (CCTA)...
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10-Year Fracture Risk in Postmenopausal Women with Osteopenia and Osteoporosis in South Korea

Baek YH, Cho SW, Jeong HE, Kim JH, Hwang Y, Lange JL, Shin JY

Background: In South Korea, women aged 66 years are eligible for complimentary bone mineral density (BMD) screening via the National Screening Program for Transitional Ages. We aimed to evaluate the...
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The 2nd Metacarpal Cortical Index as a Simple Screening Tool for Osteopenia

Patel B, Aqil A, Riaz O, Jeffers R, Dickson D

Background: Osteopenia is a known risk factor for sustaining skeletal fractures. Prevention of fragility fractures has obvious clinical and economic advantages, however screening all patients using a dual energy X-ray...
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The Role of Toll-Like Receptors in Osteoclastogenesis

Yim M

Bone homeostasis is maintained by a balance in the levels of osteoclast and osteoblast activity. Osteoclasts are bone-resorbing cells and have been shown to act as key players in various...
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Physicians’ Attitudes on Management of Osteopenia in South Korea

Ha JH, Kim HS, Won SJ, Lee YK, Koo KH

Background: Osteopenia patients have a risk of fracture and may develop osteoporosis. We investigated physicians’ management of osteopenia patients in South Korea. Methods: A survey was conducted using a questionnaire including 6...
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Inhibitory Effect of Rosae Multiflorae Fructus Extracts on the Receptor Activator of NF-κB Ligand-Induced Osteoclastogenesis through Modulation of P38- and Ca2⁺-Mediated Nuclear Factor of Activated T-Cells Cytoplasmic 1 Expression

Park KH, Gu DR, Kim MS, Lee SH

BACKGROUND: Rosae Multiflorae fructus (RMF), known to have anti-inflammatory and antioxidant properties, has been used as a traditional remedy for inflammatory diseases such as arthritis in Eastern Asia. However, its...
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Hypertrophic osteopathy in a cat with cardiac interventricular septal defect

de Sousa F, Bianchi MV, Taunde PA, Bandinelli MB, Fett RR, Driemeier , Pavarini S

A 3-year-old mixed-breed female cat was diagnosed with a ventricular septal defect of the heart through an echocardiogram. After a 9-month treatment, progressive and diffuse hard thickening of all limbs...
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The efficacy of ultrasonography in monitoring the healing of jaw lesions

Zainedeen , Al Haffar , Kochaji N, Wassouf G

PURPOSE: This study aimed to assess the reliability of ultrasonography (US) in comparison with cone-beam computed tomography (CBCT) as a tool for monitoring the healing of jaw lesions. MATERIALS AND METHODS:...
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Mesenchymal Stem Cell Therapy for Bone Regeneration

Jin YZ, Lee JH

Mesenchymal stem cells (MSCs) have been used in clinic for approximately 20 years. During this period, various new populations of MSCs have been found or manipulated. However, their characters and...
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Clinical Implication of Sarcopenia in Patients with Inflammatory Bowel Disease

Kim SE

Recent studies have shown that inflammatory bowel disease (IBD) patients are affected by altered body composition, especially low muscle mass or sarcopenia. Detection of sarcopenia is important, as it can...
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Recurrent symptomatic cemento-osseous dysplasia: A case report

Min CK, Koh KJ, Kim KA

Cemento-osseous dysplasia (COD) is a benign fibro-osseous lesion of bone, in which normal bone is replaced by fibrous tissue, followed by calcification with osseous and cementum-like tissue. COD is classified...
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Comparative Analysis of Spontaneous Infectious Spondylitis : Pyogenic versus Tuberculous

Lee Y, Kim BJ, Kim SH, Lee SH, Kim WH, Jin SW

OBJECTIVE: Spondylitis is often chemotherapy resistant and requires long-term treatment. Without adequate chemotherapy, the outcome can be fatal or result in severe neurologic damage. Therefore, differentiating the etiology of spondylitis...
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X-linked Hypophosphatemic Rickets, del(2)(q37.1;q37.3) Deletion Syndrome and Mosaic Turner Syndrome, mos 45,X/46,X, del(2)(q37.1;q37.3) in a 3-year-old Female

Vidmar AP, Miyazaki B, Sanchez-Lara PA, Pitukcheewanont P

There are currently no published cases that report concomitant Turner syndrome (TS), 2q37 deletion syndrome and X-linked hypophosphatemic rickets (XLH). Interestingly, since the clinical phenotypes of TS and 2q37 deletion...
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