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Genetics in heritable pulmonary arterial hypertension

Lee YJ

  • KMID: 2259198
  • Korean J Med.
  • 2010 Jan;78(1):20-27.
Pulmonary arterial hypertension is caused by vascular remodeling including muscularization of arteries, loss of small precapillary arteries, and formation of neointima and plexiform lesion, resulting in a progressive increase in...
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15 years journey of idiopathic pulmonary arterial hypertension with BMPR2 mutation

Ahn KJ, Jang AY, Park SJ, Chung WJ

Pulmonary arterial hypertension (PAH) is known as one of diseases with the worst prognosis. Recently, targeted PAH drugs have been developed and approved for use; therefore, the treatment strategy and...
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Field Cancerization in Sporadic Colon Cancer

Park SK, Song CS, Yang HJ, Jung YS, Choi KY, Koo DH, Kim KE, Jeong KU, Kim HO, Kim H, Chun HK, Park DI

BACKGROUND/AIMS: Aberrant DNA methylation has a specific role in field cancerization. Certain molecular markers, including secreted frizzled-related protein 2 (SFRP2), tissue factor pathway inhibitor 2 (TFPI2), N-Myc downstream-regulated gene 4...
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