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Frailty Index is Associated with Adverse Outcomes after Aortic Valve Replacement in Elderly Patients

Sohn B, Choi JW, Hwang HY, Jang MJ, Kim KH, Kim KB

BACKGROUND: This study was conducted to evaluate the prognostic value of the frailty index based on routine laboratory data (FI-L) in elderly patients who underwent surgical aortic valve replacement (SAVR). METHODS:...
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Surgical Ablation of Atrial Fibrillation in Patients Undergoing Bioprosthetic Valve Replacement

Pyo W, Park SJ, Kim WK, Kim HJ, Kim JB, Jung SH, Joo SJ, Chung CH, Lee JW

BACKGROUND: Scarce data have been reported on the efficacy of concomitant atrial fibrillation (AF) ablation in patients undergoing bioprosthetic valve replacement. METHODS: From 2001 and 2014, 146 consecutive patients (69.3±9.4 years,...
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Mechanical versus Tissue Aortic Prosthesis in Sexagenarians: Comparison of Hemodynamic and Clinical Outcomes

Son J, Cho YH, Jeong DS, Sung K, Kim WS, Lee YT, Park PW

BACKGROUND: The question of which type of prosthetic aortic valve leads to the best outcomes in patients in their 60s remains controversial. We examined the hemodynamic and clinical outcomes of...
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Early Clinical Experience with Sutureless Aortic Valve Replacement for Severe Aortic Stenosis

Kim DJ, Kim HH, Lee SY, Lee S, Chang BC

BACKGROUND: Sutureless aortic valve replacement (SU-AVR) has been developed as an alternative surgical treatment for patients with symptomatic severe aortic stenosis (AS). The aim of this study was to evaluate...
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Physicochemical characterization of porcine bone-derived grafting material and comparison with bovine xenografts for dental applications

Lee JH, Yi GS, Lee JW, Kim DJ

PURPOSE: The physicochemical properties of a xenograft are very important because they strongly influence the bone regeneration capabilities of the graft material. Even though porcine xenografts have many advantages, only...
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Effect of Rosuvastatin on Bovine Pericardial Aortic Tissue Valve Calcification in a Rat Subdermal Implantation Model

Lee SH, Kim DH, Youn YN, Lee S, Joo HC, Chang BC, Yoo KJ

BACKGROUND AND OBJECTIVES: There are pathophysiologic similarities between calcification and atherosclerosis because both are the product of an active inflammatory process. The aim of this study was to examine the...
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Early Outcomes of Sutureless Aortic Valves

Hanedan MO, Mataracı , Yürük MA, Özer T, Sayar U, Arslan AK, Ziyrek U, Yücel M

BACKGROUND: In elderly high-risk surgical patients, sutureless aortic valve replacement (AVR) should be an alternative to standard AVR. The potential advantages of sutureless aortic prostheses include reducing cross-clamping and cardiopulmonary...
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Infected Thrombus of the Bioprosthetic Aortic Valve with Distal Arterial Embolization after 3 Years of Valve Replacement Surgery

Hong JA, Kim SA

Current guidelines recommend the use of warfarin in the first 3 months after bioprosthetic valve replacement and suggest long-term anticoagulation only in patients with obvious risk factors for thrombosis. Despite...
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Valved Conduit with Glutaraldehyde-Fixed Bovine Pericardium Treated by Anticalcification Protocol

Lim HG, Kim GB, Jeong S, Kim YJ

  • KMID: 2382166
  • Korean J Thorac Cardiovasc Surg.
  • 2014 Aug;47(4):333-343.
BACKGROUND: A preclinical study was conducted for evaluating a valved conduit manufactured with a glutaraldehyde (GA)-fixed bovine pericardium treated using an anticalcification protocol. METHODS: Bovine pericardia were decellularized, fixed with GA...
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The Anti-calcification Effect of Dithiobispropionimidate, Carbodiimide and Ultraviolet Irradiation Cross-linking Compared to Glutaraldehyde in Rabbit Implantation Models

Park S, Kim SH, Lim HG, Lim C, Kim YJ

BACKGROUND: Glutaraldehyde (GA) is a widely used cross-linking agent for improving mechanical properties and resistance to enzymatic degradation of collagenous tissue, but it has several drawbacks such as calcification and...
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Changes of the Structural and Biomechanical Properties of the Bovine Pericardium after the Removal of alpha-Gal Epitopes by Decellularization and alpha-Galactosidase Treatment

Nam J, Choi SY, Sung SC, Lim HG, Park SS, Kim SH, Kim YJ

BACKGROUND: Bovine pericardium is one of the most widely used materials in bioprosthetic heart valves. Immunologic responses have been implicated as potential causes of limited durability of xenogenic valves. This...
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Histologic Characteristics and Mechanical Properties of Bovine Pericardium Treated with Decellularization and alpha-Galactosidase: A Comparative Study

Min BJ, Kim YJ, Choi JW, Choi SY, Kim SH, Lim HG

BACKGROUND: Bioprostheses for cardiovascular surgery have limitations in their use following as calicification. alpha-galactosidase epitope is known as a stimulant of immune response and then shows a progressing calcification. The...
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Echocardiography in Transcatheter Aortic Valve Implantation and Mitral Valve Clip

Siegel RJ, Luo H

Transcatheter aortic valve implantation and transcatheter mitral valve repair (MitraClip) procedures have been performed worldwide. In this paper, we review the use of two-dimensional and three-dimensional transesophageal echo for guiding...
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A Comparative Study on Mechanical and Biochemical Properties of Bovine Pericardium After Single or Double Crosslinking Treatment

Jang W, Choi S, Kim SH, Yoon E, Lim HG, Kim YJ

BACKGROUND AND OBJECTIVES: Glutaraldehyde (GA) has been used as a representative method of tissue preservation in cardiovascular surgery. However, GA has showed limited durability including calcification, mechanical failure and toxicity....
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Study on Genipin: A New Alternative Natural Crosslinking Agent for Fixing Heterograft Tissue

Yoo JS, Kim YJ, Kim SH, Choi SH

  • KMID: 2288822
  • Korean J Thorac Cardiovasc Surg.
  • 2011 Jun;44(3):197-207.
BACKGROUND: In cardiac surgery, especially in the reconstruction of vascular structures and intracardiac defects, glutaraldehyde has usually been used as the reagent for fixing porcine or bovine pericardial tissues. But...
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Effect of Trypsin on Physico-dynamic and Histological Changes after Decellularization of Bovine Pericardium

Seong YW, Kim YJ, Kim SH, Min BJ, Lee YO, Lim HG

  • KMID: 2063054
  • Korean J Thorac Cardiovasc Surg.
  • 2010 Dec;43(6):565-575.
BACKGROUND: Various decellularization methods have been studied in order to develop tissue graft which is less immunogenic and more durable. This study was performed to investigate the physico-dynamic and histological...
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Modified Bentall Operation and the Double Sewing Ring Technique: 2 case reports

Kim TY, Lee JM, Choi JB, Kim MH, Jo JK

  • KMID: 2062991
  • Korean J Thorac Cardiovasc Surg.
  • 2010 Apr;43(2):156-160.
The Bentall-DeBono operation is the technique of choice for aortic root replacement. When the patients have contraindications for lifelong anticoagulation, the biologic Bentall operation may be a good option. However,...
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Effects on Tensile Strength and Elasticity after Treatment with Glutaraldehyde, Solvent, Decellularization and Detoxification in Fresh Bovine Pericardium

Jang WS, Kim YJ, Kim SH

  • KMID: 2062961
  • Korean J Thorac Cardiovasc Surg.
  • 2010 Feb;43(1):1-10.
BACKGROUND: Bioprosthetic materials have been made using glutaraldehyde fixation of porcine or bovine pericardium during cardiovascular surgery. But these bioprostheses have the problems of calcification and mechanical failure. We determined...
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Synchronized Synergism Using Ethanol, L-lysine and NaBH4 in Glutaraldehyde Treated Porcine Pericardium

Kim KC, Kim YJ, Kim SH, Choi SH

  • KMID: 1475421
  • Korean J Thorac Cardiovasc Surg.
  • 2009 Dec;42(6):685-695.
BACKGROUND: Calcification is the most frequent cause of clinical failure of bioprosthetic tissues that are fabricated from Glutaraldehyde (GA)-fixed porcine valve or bovine pericardium. We recently used a multi-factorial approach...
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Comparison of the Uniaxial Tensile Strength, Elasticity and Thermal Stability between Glutaraldehyde and Glutaraldehyde with Solvent Fixation in Xenograft Cardiovascular Tissue

Cho S, Kim YJ, Kim SH, Park JE, Kim WH

  • KMID: 1475311
  • Korean J Thorac Cardiovasc Surg.
  • 2009 Apr;42(2):165.
BACKGROUND: With the advances of cardiac surgery, the demand for an artificial prosthesis has increased, and this has led to the development and utilization of diverse alternative materials. We conducted...
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