- Current Status and Future Trends of Cold Atmospheric Plasma as an Oncotherapy
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Dai X, Wu J, Lu L, Chen Y
- KMID: 2545707
- Biomol Ther.
- 2023 Sep;31(5):496-514.
- doi: 10.4062/biomolther.2023.027
Cold atmospheric plasma (CAP), a redox modulation tool, is capable of inhibiting a wide spectrum of cancers and has thus been proposed as an emerging onco-therapy. However, with incremental successes... -
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- Ataxia-Telangiectasia Mutated Is Involved in Autolysosome Formation
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Hwang M, Jun DW, Song BR, Shim H, Lee CH, Kim S
- KMID: 2545713
- Biomol Ther.
- 2023 Sep;31(5):559-565.
- doi: 10.4062/biomolther.2023.003
Ataxia-telangiectasia mutated (ATM), a master kinase of the DNA damage response (DDR), phosphorylates a multitude of substrates to activate signaling pathways after DNA double-strand breaks (DSBs). ATM inhibitors have been... -
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- Searching for Novel Candidate Small Molecules for Ameliorating Idiopathic Pulmonary Fibrosis: a Narrative Review
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Kim Ki, Hossain R, Li X, Lee HJ, Lee CJ
- KMID: 2545706
- Biomol Ther.
- 2023 Sep;31(5):484-495.
- doi: 10.4062/biomolther.2023.056
Idiopathic pulmonary fibrosis (IPF) can be defined as a progressive chronic pulmonary disease showing scarring in the lung parenchyma, thereby resulting in increase in mortality and decrease in the quality... -
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- Chromatographic Determination of the Absolute Configuration in Sanjoinine A That Increases Nitric Oxide Production
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Um S, Jeong H, An JS, Jo SJ, Kim YR, Oh DC, Moon K
- KMID: 2545714
- Biomol Ther.
- 2023 Sep;31(5):566-572.
- doi: 10.4062/biomolther.2023.028
A chiral derivatization strategy with phenylglycine methyl ester (PGME) was employed to develop a straightforward method to determine the absolute configurations of N,N-dimethyl amino acids. The PGME derivatives were analyzed... -
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- Phytoceramide Alleviates the Carrageenan/Kaolin-Induced Arthritic Symptoms by Modulation of Inflammation
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Sur B, Kim M, Villa T, Oh S
- KMID: 2545710
- Biomol Ther.
- 2023 Sep;31(5):536-543.
- doi: 10.4062/biomolther.2023.031
Phytoceramide (Pcer) is found mainly in plants and yeast. It can be neuroprotective and immunostimulatory on various cell types. In this study, the therapeutic effect of Pcer was explored using... -
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- Regulation of the Gene Expression of Airway MUC5AC Mucin through NF-κκB Signaling Pathway by Artesunate, an Antimalarial Agent
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Kim Ki, Hossain R, Ryu J, Lee HJ, Lee CJ
- KMID: 2545711
- Biomol Ther.
- 2023 Sep;31(5):544-549.
- doi: 10.4062/biomolther.2023.048
In this study, artesunate, an antimalarial agent, was investigated for its potential effect on the gene expression of airway MUC5AC mucin. The human pulmonary epithelial NCI-H292 cells were pretreated with... -
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- Cremastranone-Derived Homoisoflavanes Suppress the Growth of Breast Cancer Cells via Cell Cycle Arrest and Caspase-Independent Cell Death
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Choi Y, Park S, Lee S, Shin HE, Kwon S, Choi JK, Lee MH, Seo SY, Lee Y
- KMID: 2545709
- Biomol Ther.
- 2023 Sep;31(5):526-535.
- doi: 10.4062/biomolther.2023.057
Breast cancer is the most common cancer and a frequent cause of cancer-related deaths among women wordlwide. As therapeutic strategies for breast cancer have limitations, novel chemotherapeutic reagents and treatment... -
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- Aerobic Exercise Ameliorates Muscle Atrophy Induced by Methylglyoxal via Increasing Gastrocnemius and Extensor Digitorum Longus Muscle Sensitivity
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Hong SM, Lee EY, Park J, Kim J, Kim SY
- KMID: 2545715
- Biomol Ther.
- 2023 Sep;31(5):573-582.
- doi: 10.4062/biomolther.2023.130
Muscle atrophy is characterized by the loss of muscle function. Many efforts are being made to prevent muscle atrophy, and exercise is an important alternative. Methylglyoxal is a well-known causative... -
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- C-Reactive Protein Signaling Pathways in Tumor Progression
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Kim ES, Kim SY, Moon A
- KMID: 2545705
- Biomol Ther.
- 2023 Sep;31(5):473-483.
- doi: 10.4062/biomolther.2023.132
Many cancers arise from sites of chronic inflammation, which creates an inflammatory microenvironment surrounding the tumor. Inflammatory substances secreted by cells in the inflammatory environment can induce the proliferation and... -
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- Novel Effect of Hyaluronan and Proteoglycan Link Protein 1 (HAPLN1) on Hair Follicle Cells Proliferation and Hair Growth
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Ha HC, Zhou D, Fu Z, Back MJ, Jang JM, Shin IC, Kim DK
- KMID: 2545712
- Biomol Ther.
- 2023 Sep;31(5):550-558.
- doi: 10.4062/biomolther.2023.080
Hair loss is a common condition that can have a negative impact on an individual’s quality of life. The severe side effects and the low efficacy of current hair loss... -
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- Niclosamide Inhibits Aortic Valve Interstitial Cell Calcification by Interfering with the GSK-3β/β-Catenin Signaling Pathway
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Adhikari R, Shiwakoti S, Kim E, Choi IJ, Park SH, Ko JY, Chang K, Oak MH
- KMID: 2545708
- Biomol Ther.
- 2023 Sep;31(5):515-525.
- doi: 10.4062/biomolther.2022.146
The most common heart valve disorder is calcific aortic valve stenosis (CAVS), which is characterized by a narrowing of the aortic valve. Treatment with the drug molecule, in addition to... -
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