- Heme Oxygenase-1: Its Therapeutic Roles in Inflammatory Diseases
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Pae HO, Chung HT
- KMID: 2167992
- Immune Netw.
- 2009 Feb;9(1):12-19.
- doi: 10.4110/in.2009.9.1.12
Heme oxygenase (HO)-1 is an inducible enzyme that catalyzes the first and rate-limiting step in the oxidative degradation of free heme into ferrous iron, carbon monoxide (CO), and biliverdin (BV),... -
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- The Role of Oxidative Stress in the Pathogenesis of Diabetic Vascular Complications
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Sasaki S, Inoguchi T
- KMID: 2174415
- Diabetes Metab J.
- 2012 Aug;36(4):255-261.
- doi: 10.4093/dmj.2012.36.4.255
Oxidative stress has been paid increasing attention to as an important causative factor for diabetic vascular complications. Among possible various sources, accumulating evidence has indicated that NAD(P)H oxidase may be... -
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- HO-1 Mediates Intracellular Calcium Modulation and Inhibits TNF-alpha-induced NF-kappaB Activity in Human Colonic Epithelial Cell Line
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Kim YR, Jang SJ
- KMID: 2092882
- Korean J Anat.
- 2006 Oct;39(5):401-406.
Heme oxygenage-1 (HO-1) is the rate-limiting enzyme in heme catabolism, which leads to the generation of carbon monoxide (CO), biliverdin, and free iron. HO-1 has been known to show strong immunosuppressive properties... -
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- Protective Effects of Inducible HO-1 on Oxygen Toxicity in Rat Brain Endothelial Microvessel Cells
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Yoo SJ, Nakra NK, Ronnett GV, Moon C
- KMID: 2169473
- Endocrinol Metab.
- 2014 Sep;29(3):356-362.
- doi: 10.3803/EnM.2014.29.3.356
BACKGROUND: Reperfusion in ischemia is believed to generate cytotoxic oxidative stress, which mediates reperfusion injury. These stress conditions can initiate lipid peroxidation and damage to proteins, as well as promote... -
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- The Role of Heme Oxygenase-1 in Lung Cancer Cells
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Jung JH, Kim HR, Kim EJ, Hwang KE, Kim SY, Park JH, Kim HJ, Yang SH, Jeong ET
- KMID: 2318845
- Tuberc Respir Dis.
- 2006 Mar;60(3):304-313.
BACKGROUND: Heme oxygenase-1 (HO-1) is an inducible enzyme that catalyzes the oxidative degradation of heme to form biliverdin, carbon monoxide (CO), and free iron. The current evidence has indicated a... -
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- The Anti-inflammatory Effect of Cobalt-Protoporphyrin for Rats with Epididymitis Induced by Escherichia coli Infection
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Seo IY, Jeong CS, Rim JS
- KMID: 2294243
- Korean J Urol.
- 2006 Jun;47(6):656-660.
- doi: 10.4111/kju.2006.47.6.656
PURPOSE: Heme oxygenase-1 (HO-1), an inducible heat shock protein, catalyzes the heme to iron, biliverdin and carbon monoxide. It also has an inhibitory effect on necrosis and inflammation. Cobalt (III)-protoporphyrin... -
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