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The Effects of Cytochalasin B and Colchicine on Fine Structure of Bile Canaliculi and Hepatocytes in Mouse Liver

Park CH, Jang BJ, Uhm CS

  • KMID: 1530060
  • Korean J Anat.
  • 1998 Apr;31(2):241-251.
Bile canaliculi is closely related to the cytoskeleton; actin filament web, microtubules and cytokeratin intermediate filaments. To understand how cytoskeletal alteration affects bile canalicular structure, the investigators injected cytochalasin B...
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Curcumin Prevents Bile Canalicular Alterations in the Liver of Hamsters Infected with Opisthorchis viverrini

Jattujan P, Pinlaor S, Charoensuk L, Arunyanart C, Welbat JU, Chaijaroonkhanarak W

Opisthorchis viverrini infection causes inflammation and liver injury leading to periductal fibrosis. Little is known about the pathological alterations in bile canaliculi in opisthorchiasis. This study aimed to investigate bile...
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An experimental study on microcholangiographic manifestation in extrahepatic bile duct obstruction

Lee Y, Kang HS, Park JH, Kim CW

Microcholangiography using microbarium was done for radiological observation of the morphology of intrahepaticmicrobiliary system and its change after extrahepatic bile duct obstruction. Regurgitation of microbarium into the systemic circulation was...
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Ultrastructural Changes of the Cultured Hepatocytes in Microfilamentous Dysfunction induced by Drugs

Kim JG, Ko JS, Ahn ET, Park KH

  • KMID: 2092700
  • Korean J Anat.
  • 1999 Oct;32(5):661-671.
To examine the role of actin microfilaments which are located at beneath the plasma membrane, we observed the ultrastructural changes of rat hepatocyte induced by alteration of the microfilamentous integrity....
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Cholestasis beyond the Neonatal and Infancy Periods

Khalaf R, Phen C, Karjoo S, Wilsey M

Cholestasis results from impairment in the excretion of bile, which may be due to mechanical obstruction of bile flow or impairment of excretion of bile components into the bile canaliculus....
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Alteration of Bile Acid Transporter Expression in Patients with Early Cholestasis Following Living Donor Liver Transplantation

Jung ES, Kim BK, Kim SY, Lee YS, Bae SH, Yoon SK, Choi JY, Park YM, Kim DG

BACKGROUND: Intrahepatic cholestasis can occur early after living donor liver transplantation (LDLT). We investigated the changes in the expressions of the bile acid transporters and the liver histology in the...
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Morphological Changes of Cultured Rat Hepatocytes Induced by Phalloidin and Cytochalasin D

Park KH, Kim JB, Ahn ET, Ko JS, Kim JG

  • KMID: 2224528
  • Korean J Anat.
  • 2000 Dec;33(6):665-676.
The microfilaments of hepatocyte are distributed throughout the vicinity of cell membranes, especially numerous around the region of bile canaliculus, and provide the maintenance of cell shape, cellular wall tension,...
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A Study on Intrasplenic Transplantation of Embryonic Stem Cells

Choi CS, Yang YC, Choi YK

  • KMID: 2145218
  • J Korean Surg Soc.
  • 2001 May;60(5):549-557.
PURPOSE: The authors evaluated the morphological and proliferative properties of embryonic stem (ES) cells following intrasplenic transplantation. The results were compared with those obtained following intrasplenic transplantation of cultured hepatocytes. METHODS:...
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Successful mouse hepatocyte culture with sandwich collagen gel formation

Choi HJ, Choi D

PURPOSE: Primary mammalian hepatocytes largely retain their liver-specific functions when they are freshly derived from donors. However, long-term cultures of functional hepatocytes are difficult to establish. To increase the longevity...
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Increased Microfilaments in Hepatocytes and Biliary Ductular Cells in Cholestatic Liver Diseases

Chung KW, Han NI, Choi SW, Ahn BM, Yoon SK, Nam SW, Lee YS, Han JY, Sun HS

To assess the extent of microfilaments in cholestatic liver diseases we examined the cytoplasmic microfilaments in intrahepatic and extrahepatic cholestasis in man by electron microscopy. Study subjects were two...
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