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Pharmacological treatment options for acne

Park KY

Acne vulgaris is a very common condition affecting up of about 80% to 90% of adolescents. The patients with acne have been shown to be adversely impacted by the effect...
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Twice-per-week Application of an Adapalene-benzoyl Peroxide Fixed-dose Combination Gel as Maintenance Treatment for Acne Vulgaris in Adults

Seol JE, Lee W, Kang JN, Kim H

  • KMID: 2350790
  • Korean J Dermatol.
  • 2016 Feb;54(2):119-124.
BACKGROUND: The efficacy and safety of daily maintenance treatment with an adapalene-benzoyl peroxide (adapalene-BPO) fixed-dose combination gel is established in acne vulgaris in adults. OBJECTIVE: This study evaluated the efficacy and...
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Effects of Adapalene-Benzoyl Peroxide Combination Gel in Treatment or Maintenance Therapy of Moderate or Severe Acne Vulgaris: A Meta-Analysis

Zhou R, Jiang X

BACKGROUND: An antibiotic-free, fixed-dose combination gel with adapalene (A) 0.1% and benzoyl peroxide (BPO) 2.5% has been developed for treatment of acne vulgaris. OBJECTIVE: To compare the clinical outcomes of A-BPO...
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Evaluation of the Efficacy, Safety, and Treatment-Related Skin Irritation of Adapalene-Benzoyl Peroxide Combination Gel and Adapalene Gel in Acne Patients: A Randomized Comparative Study

Kim H, Kang JN, Park IH, Chun JS, Seol JE, Seo JK, Sung HS

  • KMID: 2246404
  • Korean J Dermatol.
  • 2014 Feb;52(2):106-114.
BACKGROUND: While adapalene and benzoyl peroxide have both been demonstrated to be effective for the treatment of acne vulgaris, they can also cause skin irritation, resulting in patient incompliance. In...
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Cutaneous Adverse Reactions Associated with Epidermal Growth Factor Receptor Inhibitors

Lee HJ, Sim HS, Seo JK, Lee D, Sung HS

  • KMID: 2303577
  • Korean J Dermatol.
  • 2011 Feb;49(2):131-140.
BACKGROUND: Cutaneous adverse reactions are often observed during chemotherapy with epidermal growth factor receptor (EGFR) inhibitors including papulopustular eruptions, xerosis and paronychia. OBJECTIVE: To investigate and compare the cutaneous adverse reactions...
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Pharmacologic Treatment of Acne

Suh DH

Acne is one of the most common skin diseases. It usually occurs during adolescence, but can persist into middle age. The most deleterious form can result in permanent scarring on...
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A Study of the Effectiveness in the Treatment of Mild to Moderate Severity Acne with Adapalene-benzoyl Peroxide Fixed-dose Combination Gel (Epiduo(R))

Lee YS, Sim HS, Seo JK, Lee SK

  • KMID: 2247626
  • Korean J Dermatol.
  • 2010 Dec;48(12):1068-1077.
BACKGROUND: A fixed-dose combination gel with adapalene 0.1% and benzoyl peroxide (BPO) 2.5% has been developed for once-daily treatment of acne. It is known to be effective to reduce inflammatory...
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Clinical Features of the Cutaneous Adverse Events Induced by Combination Chemotherapy that Includes Cetuximab (Erbitux(R))

Chung WK, Chang SE, Ryu MH, Lee MW, Choi JH, Moon KC, Koh JK

  • KMID: 2248022
  • Korean J Dermatol.
  • 2008 Nov;46(11):1478-1487.
BACKGROUND: Epidermal growth factor receptor (EGFR) inhibitors are associated with cutaneous adverse events, including papulopustular eruption, xerosis, paronychia, hair abnormality and mucositis. In particular, acneiform eruptions might serve as the...
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Comparative Study of Benzoyl Peroxide Versus Erythromycin in Trichomycosis Axillaris and Pubis

Kim BJ, Choi CW, Won CH, Huh CH, Kim MN, Ro BI

  • KMID: 1596197
  • Korean J Med Mycol.
  • 2005 Jun;10(2):70-75.
BACKGROUND: Trichomycosis axillaris and pubis is a bacterial infection of the hair shaft. It is characterized by nodular thickening on the hair shaft, composed of colonies of aerobic Corynebacterium. Benzoyl...
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Comparative Study of Benzoyl Peroxide Versus Clindamycin Phosphate in Treatment of Pitted Keratolysis

Kim BJ, Park KU, Kim JY, Ahn JY, Won CH, Lee JH, Rho NK, Kim SH, Cho SY, Kwon OS, Huh CH, Youn SW, Kim MN, Ro BI

  • KMID: 1596322
  • Korean J Med Mycol.
  • 2005 Dec;10(4):144-150.
BACKGROUND: Pitted keratolysis (PK) is a bacterial infection of the stratum corneum. The infection is characterized by 1 to 7 mm discrete and coalescing craterlike pits on the plantar surfaces...
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A comparative study on the properties of filler-added methacrylate polymers

Park DW, Choi BB, Kwon KR

  • KMID: 2321710
  • J Korean Acad Prosthodont.
  • 2003 Oct;41(5):606-616.
PURPOSE: The purpose of this study was to research the properties of some chemically cured methacrylate polymers such as MMA, HEMA, TEG-DMA, bis-GMA, GMA. MATERIAL AND METHOD: 5 kinds of...
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Effect of Lipid Peroxide in Skin Surface Lipid on the Clinical Aspect of Acne and Melasma

Oh CW, Hahm JH

To evaluate correlation between the amounts of lipid peroxide in skin surface lipid and clinical aspect of lipid-relating cutaneous disorders, such as melasma and acne, skin surface lipid samples were...
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In Vitro Effects of Several Irritants Using Human Keratinocyte Culture Model

Eun HC, Choi SW, Lee AY, Lee MC

  • KMID: 1680710
  • Korean J Dermatol.
  • 1990 Aug;28(4):408-418.
Primary irritant dermatitis is one of the most common skin disease caused by various hazardous chemicals produced from the environment. For the detection of skin irritant potency, in vivo models...
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The Effect of Zinc Sulfate in Acnd Vulgaris

Chun KH, Lee CJ, Houh W

  • KMID: 1678210
  • Korean J Dermatol.
  • 1981 Apr;19(2):175-181.
In order to evaluate the effect of zinc sulfate on acne vulgaris, this study was performed during 3 months' period from October, 1979 to December 31, 1979. Total number of...
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Five Cases with Adverse Reaction Due to Benzoyl Peroxide

Kim JK, Kook HI

  • KMID: 1678337
  • Korean J Dermatol.
  • 1981 Oct;19(5):791-795.
No abstract available.
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A Clinical Study of Panoxyl 2.5(R) in Acne Vulgaris

Cho KH, Nam TJ, Kim WS, Kim HS, Lee YS

  • KMID: 1677880
  • Korean J Dermatol.
  • 1979 Jun;17(3):155-170.
Bezoyl peroxide, a powerful oxidizing agent, has been uaed topically in the treatment of acne vulgaris as a cream or lotion and has been shown to he effective for this...
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Clinical Effects of Benoxal (Benzoyl peroxide) on Acne Vulgaris

Nam TJ, Moon KC, Kim JM, Kim WS, Lee YS

  • KMID: 1677781
  • Korean J Dermatol.
  • 1978 Dec;16(6):459-463.
Benzoyl peroxide has been known to have bacteriostatic activity against Corynebacterium acnes and to have comedolytic action in patients with acne vulgaris. The present study was undertaken to evaluate the...
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