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Drug Therapy for Obesity

Kim KS, Park SW

  • KMID: 2270999
  • Korean J Obes.
  • 2012 Dec;21(4):197-202.
Obesity is associated with a substantial increase in metabolic disorders and various cancers. As weight loss achieved with lifestyle intervention is modest, there is a need for drug treatment. Orlistat, phentermine,...
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Craving and treatment in smoking

Kim MH, Min S

Craving has been well known to be the most important clinical phenomenon in smoking cessation treatment and one that physicians always encounter. For successful and prolonged abstinence, understanding, evaluation, and...
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V2 Receptor Antagonist; Tolvaptan

Yi JH, Shin HJ, Kim HJ

Hyponatremia is the most common electrolyte disorder in hospitalized patients. Many studies documented that it was related to increased morbidity and mortality in patients with congestive heart failure, liver cirrhosis,...
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Behavioral Intervention and Anti-Obesity Drug Therapy

Kim MK

  • KMID: 2267840
  • Korean J Med.
  • 2013 May;84(5):624-628.
Obesity is associated with a reduction in life expectancy and an increase in mortality from cardiovascular diseases, cancer, and other causes. The U.S. Preventive Service Task Force (USPSTF) recommends screening...
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Rapid Changes in D1 and D2 Dopamine Receptor Binding in Striatal Subregions after a Single Dose of Phencyclidine

Dalton VS, Zavitsanou K

  • KMID: 2171262
  • Clin Psychopharmacol Neurosci.
  • 2011 Aug;9(2):67-72.
OBJECTIVE: In humans, a single exposure to phencyclidine (PCP) can induce a schizophrenia-like psychosis which can persist for up to two weeks. In rats, an acute dose of PCP increases...
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Smoking Cessation Rate and Related Factors of Varenicline in Clinical Practice

Song B, Yun WS, Choi EY, Cheong YS, Park EW

BACKGROUND: Varenicline is recently known as smoking cessation medicine has no results of researches conducted in the actual practice settings except for incipient clinical trials. This research attempted to analyze...
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Interactions of Dopamine D1 and N-methyl-D-Aspartate Receptors are Required for Acute Cocaine-Evoked Nitric Oxide Efflux in the Dorsal Striatum

Lee DK, Ahn SM, Shim YB, Koh WC, Shim I, Choe ES

Alterations in nitric oxide (NO) release in response to psychostimulants in the striatum cause a plastic change contributing to the development and expression of addiction. In this study, regulation of...
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Weight Loss Drugs Recently Approved by the FDA

Lee CB

There have been many advances in obesity treatment, including life-style modification and pharmacological and surgical treatments. It seems that the most remarkable advances in obesity treatment are those of pharmacological...
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Role of Dopamine Receptors on Electroencephalographic Changes Produced by Repetitive Apomorphine Treatments in Rats

Jang HS, Kim JY, Kim SH, Lee MG

Repeated psychostimulants induce electroencephalographic (EEG) changes, which reflect adaptation of the neural substrate related to dopaminergic pathways. To study the role of dopamine receptors in EEG changes, we examined the...
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Exposure to Extremely Low Frequency Magnetic Fields Induces Fos-Related Antigen-Immunoreactivity Via Activation of Dopaminergic D1 Receptor

Shin EJ, Nguyen XK, Nguyen TT, Pham DT, Kim HC

We previously demonstrated that repeated exposure to extremely low frequency magnetic fields (ELF-MF) increases locomotor activity via stimulation of dopaminergic D1 receptor (J. Pharmacol. Sci., 2007;105:367-371). Since it has been...
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Gap Junction Contributions to the Goldfish Electroretinogram at the Photopic Illumination Level

Kim DY, Jung CS

Understanding how the b-wave of the electroretinogram (ERG) is generated by full-field light stimulation is still a challenge in visual neuroscience. To understand more about the origin of the b-wave,...
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Effect of Multi-modal Interventions for Smoking Cessation in a University Setting: A Short Course of Varenicline, Financial Incentives, E-mail and Short Message Service

Cheong YS, Ahn SH

BACKGROUND: Varenicline is known to have higher effect for smoking cessation than existing pharmacotherapies, including Bupropion and Nicotine replacement therapy, however, it can also bring about adverse effects such as...
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Adherence to Varenicline and Abstinence Rates for Quitting Smoking in a Private Health Promotion Center-Based Smoking Cessation Clinic

Lee JY, Kim MJ, Jun HJ, Kang M, Park AR, Oh DE, Choi YH, Hwang JH

  • KMID: 2319816
  • Tuberc Respir Dis.
  • 2012 May;72(5):426-432.
BACKGROUND: Varenicline is an effective smoking cessation aid. However, smokers prescribed with varenicline do not always receive varenicline for 12 weeks, as recommended. This study analyzed the subjects who received...
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Roles of Dopaminergic D1 and D2 Receptors in Catecholamine Release from the Rat Adrenal Medulla

Baek YJ, Seo YS, Lim DY

The aim of the present study was designed to establish comparatively the inhibitory effects of D1-like and D2-like dopaminergic receptor agonists, SKF81297 and R(-)-TNPA on the release of catecholamines (CA)...
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Different Regulation of Atrial ANP Release through Neuropeptide Y2 and Y4 Receptors

Piao FL, Yuan K, Bai GY, Han JH, Park WH, Kim SH

Neuropeptide Y (NPY) receptors are present in cardiac membranes. However, its physiological roles in the heart are not clear. The aim of this study was to define the direct effects...
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