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ABCB1 and BMI1 mRNA expression in patients with chronic myeloid leukemia: impact on imatinib efficacy

Bedewy AM, Elmaghraby SM, Kandil NS

BACKGROUND: ATP-binding cassette transporters are important in the mechanism of multidrug resistance. ABCB1 displays a high affinity for imatinib. BMI1 is a polycomb group protein thought to be overexpressed in...
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The prognostic value of glucocorticoid receptors for adult acute lymphoblastic leukemia

Bedewy AM, EL-Maghraby SM, Kandil NS, El-Bendary WR

BACKGROUND: Therapeutic protocols used in adult acute lymphoblastic leukemia (ALL) are widely variable, and glucocorticoids (GCs) are essential components in ALL treatment. Therefore, this study aimed to evaluate the distribution...
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