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In Situ Follicular Lymphoma Developed after Hodgkin Lymphoma

Park HS, Noh SJ, Kwak JY, Song EK, Sohn MH, Lee H, Moon WS, Jang KY

In situ follicular lymphoma is a newly defined entity among the lymphoid neoplasms and is defined as architecturally normal-appearing lymph nodes and other lymphoid tissues that have one or more...
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Increased Proliferating Activity and Bcl-2 Protein Expression in Eutopic Endometrium with Endometriosis

Kim MR, Lee JH, Seo SS, Chang HJ, Hwang KJ, Kim YA, Park DW

  • KMID: 2272655
  • Korean J Obstet Gynecol.
  • 2005 Aug;48(8):1942-1949.
OBJECTIVE: To evaluate the expression of proliferating activity and Bcl-2 protein property in eutopic endometrium with endometriosis. METHODS: Endometrial tissues were obtained for endometrial biopsy from 2 groups of women. The...
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An Analysis of p53, bcl-2 and Ki-67 Expressions, and Apoptosis in Rectal Cancer: Their Correlation with the Tumor Response after Preoperative Radiochemotherapy

Yoo J, Kim SZ, Cho HM, Kim SW, Chin HM, Lee JY, Kim JK, Kang SJ, Chun CS, Kang CS

  • KMID: 1855943
  • Korean J Pathol.
  • 2005 Aug;39(4):222-228.
Background : Preoperative radiochemotherapy (RCT) has been administered for locally advanced rectal cancer to increase the therapeutic benefits, and to preserve the sphincter in low-lying tumors, however, tumor responses after...
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Apoptosis in Autosomal Dominant Polycystic Kidney Disease

Lhee HY, Lee KB, Kim H, Chae SW, Park MH

  • KMID: 2254246
  • Korean J Nephrol.
  • 2005 May;24(3):366-374.
BACKGROUND: Apoptosis is one of the major histopathologic features of autosomal dominant polycystic kidney disease (ADPKD) and may be causally related to the cystogenesis and the progressive deterioration of the...
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The Activation of ERK1/2 Via Tyrosine Kinase Pathway Attenuates TRAIL-induced Apoptosis in HeLa cell

Noh YH, Lee MW, Kim DS, Lee DY, Kim SW, Kang YK, Sohn DS, Park SC, Chung YH, Kim KY, Kim SS, Lee WB

  • KMID: 1609461
  • Korean J Phys Anthropol.
  • 2004 Sep;17(3):187-196.
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) serves as an extracellular signal triggering apoptosis in tumor cells. To characterize the molecular events involved in TRAIL-induced apoptotic signaling, we investigated the role...
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The Expression of c-myc, bcl-2 and p53 Proteins in Adenocarcinomas of Lung

Yoo J, Jung JH, Choi HJ, Kang SJ, Kang CS

  • KMID: 2127915
  • Cancer Res Treat.
  • 2004 Apr;36(2):146-150.
PURPOSE: c-myc, bcl-2 and p53 are known to regulate apoptosis. There has been growing interest in analyzing their contribution to the pathogenesis and prognosis in a variety of human cancers....
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Expression of p53, bcl-2 Protein in Small Cell Lung Cancer (SCLC) Cell Lines in Relation to Sensitivity to Chemotherapy

Woo IS, Park MJ, Park YS, Jung SW, Yeo MA, Park SH, Kim SY, Yoon HJ, Cho KS, Park JK, Kim YI

  • KMID: 1815307
  • J Korean Cancer Assoc.
  • 2000 Oct;32(5):904-910.
PURPOSE: Sensitivity of tumor cells to chemotherapeutic regimen may be accentuated by their abnormal expression of oncogene. p53 is required for the efficient activation of apoptosis following irradiation or treatment...
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The Role of bcl-2 and p53 in Tamoxifen-Induced Apoptosis of Human Breast Cancer Cell Lines

Noh WC, Noh DY, Ham YH, Kim CM, Paik NS, Moon NM, Choe KJ

  • KMID: 2175017
  • J Korean Cancer Assoc.
  • 2000 Jun;32(3):531-538.
PURPOSE: Tamoxifen has been well known as an effective anti-tumor agent against breast cancer. The important role of bcl-2 and p53 proteins in tamoxifen-induced apoptosis of breast cancer cells has been suggested....
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Expression of p53, p21/WAF1, bcl-2 and Loss of Heterozygosity for the Study of Apoptosis in Gastric Carcinoma

Yu HJ, Lee JH, Kim WH, Choe KJ, Kim JP

  • KMID: 2175008
  • J Korean Cancer Assoc.
  • 2000 Jun;32(3):447-457.
PURPOSE: The purpose of this study was to correlate the immunohistdegrees Chemical expressions of p53, p21 and bcl-2, with their loss of heterozygosity (LOH) and clinical significance. MATERIALS AND METHODS: Paraffin-embedded tissue...
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Apoptosis, P53, bax and Bcl-2 Protein Expressions in Neonatal rat Hippocampus by Kainic Acid-induced Seizure

Yun SW, Chae SA, Choi ES, Yoo BH

  • KMID: 1946278
  • J Korean Pediatr Soc.
  • 2000 Jan;43(1):85-96.
PURPOSE: Apoptosis is a process of active cell death which has been suggested to be part of hippocampal cell loss caused by kainic acid (KA). Immature rats showed higher susceptibility...
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Type of Intestinal Metaplasia in the Surrounding Mucosa of Gastric Carcinoma and Expression of bcl-2, p53 and c-erbB-2 Prtein in Gastric Carcinoma

Cho SC, Kwon KY

  • KMID: 2059286
  • J Korean Cancer Assoc.
  • 1999 Oct;31(5):898-911.
PURPOSE: This study was carried out to clarify significance of types of intestinal metaplasia and roles of bcl-2, p53 and c-erbB-2 protein in the development of gastric carcinoma. MATERIALS AND METHODS:...
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Expression of bcl-2 , p53 Protein and Aggressiveness in Thymic Epithelial Tumor

Cho SR, Jeon DH

  • KMID: 2288935
  • Korean J Thorac Cardiovasc Surg.
  • 1999 Aug;32(8):726-731.
BACKGROUND: The distinction between non-invasive and invasive or thymic carcinoma has been severely compromised by lack of objective morphological criteria. A reliable biological marker of tumor aggressiveness is, therefore, mandatory...
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Clinical Significance of bcl-2 and p53 protein Expression in Patients with Malignant Lymphoma

Hong SY, Hong DS, Kim SJ, Park SK, Lee GT, Kim DJ, Won JH, Suh WS, Baick SH, Park HS

  • KMID: 1534089
  • Korean J Hematol.
  • 1999 Feb;34(1):43-51.
BACKGROUND: Overexpression of bcl-2 protein is observed both in follicular lymphoma, in which bcl-2 has usually undergone a translocation t (14;18). The experimental findings that transfection of bcl-2 in to...
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Correlation between Expression of p53 and Bcl-2 Protein and Epstein-Barr Virus Detection in Gastric Adenocarcinoma

Yun KJ, Han WC, Moon HB, Juhng SW

  • KMID: 1725420
  • Korean J Pathol.
  • 1998 Aug;32(8):574-580.
Epstein-Barr virus (EBV) has been known to be associated with a wide variety of neoplastic conditions including nasopharyngeal carcinoma, Hodgkin's disease, and non-Hodgkin's lymphoma. Recent studies reveal the presence of...
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Expression of bcl-2 Protein in Gastric Adenoma and Adenocarcinoma

Kim YS, Kim BK, Shim SI

  • KMID: 2037281
  • Korean J Pathol.
  • 1998 Apr;32(4):248-254.
The bcl-2 oncoprotein confers a survival advantage to cells by blocking programmed cell death. Overexpression of bcl-2 probably plays a role in tumorigenesis, and the expression of the bcl-2 protein...
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Histopathologic Findings & Expression of bcl-2 of the Endometrium Analysis of 1,000 consecutive biopsies of uterine bleeding

Lee HK, Lee DG, Lee H, Shim SI

  • KMID: 1921807
  • Korean J Pathol.
  • 1998 Mar;32(3):208-214.
We evaluated 1,000 consecutive endometrial curettage samples obtained over a 30 month period. The clinico-pathologic correlation was analysed according to Hendrickson's five criteria based on the practical view. The causes...
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Expression Status and Prognostic Value of bcl-2 Protein in Breast Cancer

Lee US, Min YK, Bae JW, Koo BH, Whang CW, Kim CW

  • KMID: 1940073
  • J Korean Surg Soc.
  • 1997 Nov;53(5):622-630.
The bcl-2 proto-oncogene was first described as a result of the chromosomal translocation t(14:18) seen in a large number of follicular B-cell lines. Bcl-2 is so far unique a proto-oncogene...
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Bcl-2 Expression of the Primary Cutaneous Malignancies

Kim SH, Kang H, Son SJ

  • KMID: 2115994
  • Korean J Dermatol.
  • 1997 Oct;35(5):847-853.
No abstract available.
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Expression of Epstein-Barr Virus Gene Products, Bcl-2 and p53 Proteins in Nasopharyngeal Carcinomas

Yoon SH, Suh KS, Lee CH

  • KMID: 2275742
  • Korean J Pathol.
  • 1997 Aug;31(8):723-734.
The authors studied EBV genome expression in 40 conventionally processed samples of nasopharyngeal carcinomas (NPC), using in situ hybridization for EBERs and immunohistochemistry for LMP, Bcl-2 and p53 proteins. The...
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Histopathologic Re-evaluation of Thymoma with Immunonhistochemical Study for bcl-2 and MIC-2 Protein

Yang KM, Cho MY, Hong SW, Kim TS, Park CI, Yang WI

  • KMID: 2073679
  • Korean J Pathol.
  • 1997 May;31(5):446-461.
We reviewed 86 thymic epithelial tumors and reclassified them according to the Kirchner and Muller- Hermelink classification. They were subtyped as medullary, mixed, predominantly cortical (organoid), cortical, well differentiated thymic...
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