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Historical perspective and recent progress in cardiac ion channelopathies research and clinical practice in Hong Kong

Kit Leung K, Huang H, Chung C, Radford D, Lakhani I, Hou Li C, Kei Li T, Ranjithkumar S, Rajan R, Roever L, Garcia‑Zamora S, Bazoukis G, Liu T

Cardiac ion channelopathies encompass a set of inherited or acquired conditions that are due to dysfunction in ion channels or their associated proteins, typically in the presence of structurally normal...
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Clinical significance, challenges and limitations in using artificial intelligence for electrocardiography‑based diagnosis

Chung C, Lee S, King E, Liu T, Armoundas A, Bazoukis G, Tse G

Cardiovascular diseases are one of the leading global causes of mortality. Currently, clinicians rely on their own analyses or automated analyses of the electrocardiogram (ECG) to obtain a diagnosis. However,...
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Machine learning techniques for arrhythmic risk stratification: a review of the literature

Chung C, Bazoukis G, Lee S, Liu Y, Liu T, Letsas K, Armoundas A, Tse G

Ventricular arrhythmias (VAs) and sudden cardiac death (SCD) are significant adverse events that affect the morbidity and mortality of both the general population and patients with predisposing cardiovascular risk factors....
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Electrocardiographic features in SCN5A mutation‑positive patients with Brugada and early repolarization syndromes: a systematic review and meta‑analysis

Radford D, Chou O, Bazoukis G, Letsas K, Liu T, Tse G, Lee S

Background: Early repolarization syndrome (ERS) and Brugada syndrome (BrS) are both J-wave syndromes. Both can involve mutations in the SCN5A gene but may exhibit distinct electrocardiographic (ECG) differences. The aim...
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