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Analysis of the Microbiome of the Ear Canal in Normal Individuals and Patients with Chronic Otitis Externa

Lee JS, Lee SM, Son HS, Yoon YN, Shin JE, Sul WJ, Yu DA, Choe YB, Lee YW

Background: Recently, microbiome research has been actively conducted for various skin areas. However, no study has yet compared the microbiome of bacteria and fungi in the ear canal of healthy...
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Lytic Bacteriophage as a Biomaterial to Prevent Biofilm Formation and Promote Neural Growth

Liu ZH, Chiang MT, Lin HY

BACKGROUND Although non-lytic filamentous bacteriophages have been made into biomaterial to guide tissue growth, they had limited ability to prevent bacterial infection. In this work a lytic bacteriophage was used...
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Antibiotics for multidrug-resistant gram-negative bacteria

Kang CI

Background: Increase in antimicrobial-resistant bacteria continues to be challenge to physicians. Particularly, multidrug-resistant (MDR) gram-negative bacilli (GNB), such as extended-spectrum beta-lactamase (ESBL)-producers and carbapenem-resistant pathogens, are becoming a major human...
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Antibiotics for multidrug-resistant gram-positive bacteria

Song KH

Background: Antimicrobial resistance is a major global threat to public health and is associated with increased morbidity and mortality. A few therapeutic options for the treatment of multidrug resistant (MDR)...
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Current status of multidrug-resistant bacteria

Kim D, Jeong SH

Background: The dissemination of multidrug-resistant (MDR) pathogen is of major public health concern as it leads to increased mortality rate, length of hospital stays, and medical expenses. Current Concepts: Korean Government...
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Multidrug-resistant bacteria: a national challenge requiring urgent addressal

Kim NJ

Background: Multidrug-resistant bacterial infections are a worldwide threat owing to their increased prevalence, and poor prognosis due to inadequate antibacterial drugs. Current Concepts: Until 2019, several new antibacterial agents, targeting gram-positive...
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Why Should We Consider Potential Roles of Oral Bacteria in the Pathogenesis of Sjögren Syndrome?

Chang SH, Park SH, Cho ML, Choi Y

Sjögren syndrome (SS) is a chronic autoimmune disorder that primarily targets the salivary and lacrimal glands. The pathology of these exocrine glands is characterized by periductal focal lymphocytic infiltrates, and...
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Microbiological Contamination Assessment of School Cafeterias in the Gyeongnam Area: Investigation of the Status of Hygiene Management since COVID-19

Son YJ, Nam SJ, Lee SH, Kim DW, Shin SH, Koo OK

School meals are prepared based using the HACCP system, which is designed to ensure the physical and mental health of students. However, operational recommendations in school cafeterias have changed due...
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Lysozyme hydrochloride 0.01%, sodium fluoride 0.02%, cetylpyridinium chloride 0.05% antibacterial and sterilizing effect of mouth freshener

Park HW, Cho JW, Yoo HJ, Jeon YM, Shin KH, Ha SM

Objectives: This study aimed to assess the antibacterial, bactericidal, and mouth freshener effects of lysozyme hydrochloride 0.01%, sodium fluoride 0.02%, and cetylpyridinium chloride 0.05%. Methods: Eight oral disease-related bacteria were cultivated...
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Effect of Gentamicin Collagen Sponge on Wound Healing: In Vivo Study and Assessment of Its Effectiveness against Nosocomial Bacteria

Lee HM, Park JW, Na YC, Yoon CS, Kim JH, Park JH

Background: Gentamicin collagen sponge (Genta-Coll) reportedly has a hemostatic effect and promotes wound healing. However, it may also interfere with wound healing by causing foreign body reactions. We planned to...
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Relationship between Obesity, Gingival Inflammation, and Periodontal Bacteria after 4-Week Weight Control Program in 20’s

Seo MS, Hwang SJ

Background: Obesity weakens acquired immunity and causes infection. This study aimed to investigate the relationship between the inflammatory markers in the gingival crevicular fluid and serum and periodontal bacteria in...
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Inhibitory Effects of Copper, Brass, and Stainless Steel Surfaces on Multidrug-Resistant Microorganisms

Kim JB, Kim JK, Lee J, Chae HS, Lee HK, Park Y

Background: The aim of this study was to analyze the inhibitory effects of copper, brass (78% copper, 22% tin), and stainless steel surfaces on multidrug-resistant Acinetobacter baumannii (MRAB), extended-spectrum beta-lactamase...
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Book Review: “The New Microbiology: From Microbiomes to CRISPR”

Kang JO

At the time when owing to COVID-19 pandemic, the public is more interested in infectious diseases and pathogens than in any other period, a book titled “The New Microbiology: From...
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Bloodstream Infections in Patients with Hematologic Diseases: Causative Organisms and Factors Associated with Resistance

Choi H, Ahn H, Lee R, Cho SY, Lee DG

Background: Patients with hematologic diseases are at high risk of bloodstream infections (BSIs). This study aimed to analyze clinical features and distributions of microorganisms in patients with hematologic diseases presenting...
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The color stability and antibacterial of provisional polyethyl methacrylate (PEMA) resin with zirconia nanoparticles

Kim HS, Lee SK, Jang W, Park C, Lim HP

Purpose: This study aimed to evaluate the color stability and antibacterial properties of the surface of polyethyl methacrylate (PEMA) resin with zirconia nanoparticles added. Materials and Methods: The control group...
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Multidrug-Resistant Gram-Negative Bacterial Infections in a Tertiary-Care Hospital in Northern Ghana: A Three-Year Retrospective Analysis

Osei KM, Choi H, Zeyeh DE, Alikamatu S, Boateng EO, Nov V, Nguyen LP, Kubura K, Bobzah B, Yong D

Background: A variety of clinically important pathogens have developed multidrug resistance (MDR), which threatens global public health. This study aimed to determine the incidence, patterns, and trends of MDR of...
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Usefulness of Stool Multiplex Polymerase Chain Reaction Assays in Patients with Acute Diarrhea

Kim SH, Kim YS, Kim SH, Yoon WE, Myung HJ, Moon JS, Whang DH

Background/Aims: There is a recent increase in the use of stool multiplex PCR assay-based diagnostic tests in patients with acute diarrhea. We used multiplex PCR assays to analyze the distribution...
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Tracing surrogate bacteria inoculated on hide through the beef slaughtering process

Kim S, Kim S, Kim SK, Choi K, Kim J, Choe N

Many countries have imposed regulations relating to concerns that hide contamination will affect the cleanliness of abattoirs. However, South Korea has not indicated any clear criteria. The purpose of this...
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Relationship between high bile juice amylase levels and chronic bacterial infections in patients with gallbladder cancer

Park YM, Seo HI, Kim S, Hong SB, Lee NK, Kim DU, Han SY, Lee SJ, Kim JR

Purpose: Pancreatic enzyme reflux into the biliary tract is associated with chronic inflammation and increased cellular proliferation in the biliary epithelium, leading to biliary carcinoma. We evaluated the relationship between...
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Urgent need for novel antibiotics in Republic of Korea to combat multidrug-resistant bacteria

Lee HJ, Lee DG

Multidrug resistance in bacteria is an important issue and is increasing in frequency worldwide because of the limitations of therapeutic agents. From 2010 to 2019, 14 new systemic antibiotics received...
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