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Analysis of the NF-kappaB and Apoptosis Inducing Genes in Bladder Tumor

Jung P, Han KH, Yun SJ, Kim YJ, Lee SC, Lee HL, Kim WJ

PURPOSE: A multi-subunit transcription factor NF-kappaB mediates the antiapoptotic signals in several cancer cell lines and it is activated in a broad range of human tumors. In this study, we...
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The Mechanism of Intracellular Signal Pathway that Baicalin Hydrate Elevate Chemotherapeutic Response of Cervical Carcinoma

Kim BR, Kim IS, Ko KH, Lee JJ, Kim HG, Park RG

  • KMID: 2076936
  • Korean J Obstet Gynecol.
  • 2003 Oct;46(10):1965-1974.
Baicalin is flavonoid and major component of PC-SPES. Flavonoids including baicalin have been reported to not only function as anti-oxidant but also cause cytotoxic effect. Baicalin hydrate has been reported...
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Erratum: The Effect of Lowering the Threshold for Diagnosis of Impaired Fasting Glucose

Kim SH, Shim WS, Kim EA, Kim EJ, Lee SH, Hong SB, Kim YS, Park SG, Leem JH, Lee HJ, Nam M

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Therapeutic Modulation of Apoptosis: Targeting the BCL-2 Family at the Interface of the Mitochondrial Membrane

Nemec KN, Khaled AR

A vast portion of human disease results when the process of apoptosis is defective. Disorders resulting from inappropriate cell death range from autoimmune and neurodegenerative conditions to heart disease. Conversely,...
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Mycophenolic acid mediated mitochondrial membrane potential transition change lead to T lymphocyte apoptosis

Choi SJ, Lee HK, Kim NH, Chung SY

PURPOSE: This study demonstrated that apoptosis induced by mycophenolic acid (MPA) is mediated by mitochondrial membrane potential transition (MPT) changes in Jurkat cells. METHODS: Cell viability and MPT changes were measured...
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Cap-independent protein translation is initially responsible for 4-(N-methylnitrosamino)-1-(3-pyridyl)-butanone (NNK)-induced apoptosis in normal human bronchial pithelial cells

Moon SH, Kim HW, Kim JS, Park JH, Kim H, Eu GJ, Cho HS, Kang GM, Lee KH, Cho MH

  • KMID: 1093633
  • J Vet Sci.
  • 2004 Dec;5(4):369-378.
Evidences show that eukaryotic mRNAs can perform protein translation through internal ribosome entry sites (IRES). 5'-Untranslated region of the mRNA encoding apoptotic protease-activating factor 1 (Apaf-1) contains IRES, and, thus,...
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