- Repeated Morphine Administration Increases TRPV1 mRNA Expression and Autoradiographic Binding at Supraspinal Sites in the Pain Pathway
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Nguyen TL, Nam YS, Lee SY, Jang CG
- KMID: 2530997
- Biomol Ther.
- 2022 Jul;30(4):328-333.
- doi: 10.4062/biomolther.2022.014
Repeated morphine administration induces tolerance to its analgesic effects. A previous study reported that repeated morphine treatment activates transient receptor potential vanilloid type 1 (TRPV1) expression in the sciatic nerve,... -
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- Rapid Changes in D1 and D2 Dopamine Receptor Binding in Striatal Subregions after a Single Dose of Phencyclidine
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Dalton VS, Zavitsanou K
- KMID: 2171262
- Clin Psychopharmacol Neurosci.
- 2011 Aug;9(2):67-72.
OBJECTIVE: In humans, a single exposure to phencyclidine (PCP) can induce a schizophrenia-like psychosis which can persist for up to two weeks. In rats, an acute dose of PCP increases... -
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- Feasibility of Reflecting Improvement of Tumor Hypoxia by Mild Hyperthermia in Experimental Mouse Tumors with 18F-Fluoromisonidazole
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Lee SW, Ryu JS, Oh SJ, Im KC, Chen GJ, Lee SR, Song DY, Im SJ, Moon ES, Kim JH, Ahn SD, Shin SS, Lee KR, Moon DH, Choi EK
- KMID: 2198575
- J Korean Soc Ther Radiol Oncol.
- 2004 Dec;22(4):288-297.
PURPOSE: The aims of this study were to evaluate the change of [18F]fluoromisonidazole ([18F]FMISO) uptake in C3H mouse squamous cell carcinoma-VII (SCC-VII) treated with mild hyperthermia (42oC) and nicotinamide and... -
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- Electron Microscopic Autoradiographic Study on the Secretion of Atrial Specific Granules from Atrial Cardiocytes in Dehydrated Rats
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Shin HY, Song CH, Kim HT, Han EH, Lim JW, Lee MS
- KMID: 2224504
- Korean J Anat.
- 2004 Jun;37(3):241-253.
This study was performed to investigate for the effect of dehydration on the synthesis, secretion and secreted pathway of atrial specific granules contained ANP by electron microscopic autoradiography. Male Sprague-Dawley... -
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- The Temporospatial Distribution of Glutamate Receptors and the Effect of MK-801 on Glutamate Receptors Activation in Kainate-induced Seizure Model: Quantitative Receptor Autoradiography of Ionotropic Glutamate Receptors
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Kim MK, Kim BC, Sohn EJ, Cho KH, Lee MC
- KMID: 2342953
- J Korean Neurol Assoc.
- 2002 Mar;20(2):179-186.
BACKGROUND: Excitotoxicity and epileptogenesis have often been associated with glutamate receptor activation. Some evidence indicates that selective down regulation of AMPA receptor may be the mechanism of delayed neuronal cell... -
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- Chromatin Pattern-Dependent mRNA Synthesis in HeLa Cells and HeLa Tumors
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Lee JH, Kang MW, Choi C, Juhng SW
- KMID: 2172398
- Chonnam Med J.
- 2001 Dec;37(4):351-356.
Malignant cell nuclei, in general, have increased amount of heterochromatin and decreased electron density of euchromatin, making the chromatin pattern coarser than that of benign cell nuclei. Chromatin pattern in... -
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- Effects of Bacillus Calmette-Guerin (BCG) on the Spleen of Mouse Inoculated with Ehrlich Carcinoma Cells: A Morphological Study
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Ko JS, Park SH, Ahn ET, Park KH, Kim JG
- KMID: 2092774
- Korean J Anat.
- 2001 Oct;34(5):451-465.
This experiment was performed to study the morphological responses of the spleen of mouse inoculated with Ehrlich carcinoma cells, following administration of Bacillus Calmette-Guerin (BCG). Healthy adult ICR mice weighing... -
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- mRNA is Synthesized Mainly at the Phase between the Euchromatin and Heterochromatin: Proposal of a Phase Theory
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Kim MS, Juhng SW
- KMID: 2275638
- Korean J Pathol.
- 2001 Apr;35(2):93-97.
BACKGROUND: Malignant cell nuclei, in general, have increased amounts of heterochromatin and decreased electron densities of euchromatin, making the chromatin pattern coarser than that of benign cell nuclei. The... -
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- Effects of Lower Dose-Injections of Acriflavine-Guanosine Compound (AG60) on the DNA Synthesis and Ultrastructure of the Ehrlich Carcinoma Cells Inoculated to the Mouse
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Ahn ET, Cheong KS, Ko JS, Park KH, Kim JG
- KMID: 2224527
- Korean J Anat.
- 2000 Dec;33(6):651-664.
AG60, a recently introduced anti-cancer compound, was reported to show highly effective anti-cancer activities, when injected with doses from 30 mg/kg to 5 mg/kg.The purpose of this study was to... -
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- Changes of the level of G protein alpha-subunit mRNA by withdrawal from morphine and butorphanol
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Oh S
- KMID: 1917022
- Korean J Physiol Pharmacol.
- 2000 Aug;4(4):291-299.
Morphine or butorphanol was continuously infused into cerebroventricle (i.c.v.) with the rate of 26 nmol/microliter/h for 3 days, and the withdrawal from opioid was rendered 7 hrs after the stopping of infusion.... -
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- Quantitative Autoradiography on Ontogenic Development of alpha-Adrenoceptor in the Rat Cerebral Cortex
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Lee MK, Lee SW, Kook JH, Chung YY, Lee EJ, Kim JK, Bae CS
- KMID: 2092708
- Korean J Anat.
- 1999 Oct;32(5):749-760.
Adrenoceptors mediate response to catecholamines throughout the body. To investigate postnatal ontogenic development of alpha1- and alpha2- adrenoceptors in the rat cerebral cortex, in vitro autoradiography was done on frontal,... -
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- Biodistribution of Iodine-131-Iodomisonidazole and Imaging of Tumor Hypoxia in Mice bearing CT-26 Adenocarcinoma
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Kim HW, Kim CG, Yoon KH, Kim HJ, Juhng SK, Roh BS, Yang DJ, Kim EE, Lee HC
- KMID: 1926584
- Korean J Nucl Med.
- 1999 Jun;33(3):289-297.
urpose: Misonidazole is a radiosensitizer that binds in hypoxic cells. The purpose of this study was to find out the feasibility of I-131-Iodomisonidazole (IMISO) for imaging of tumor hypoxia. MATERIALS... -
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- Atrial Natriuretic Peptide System in Eyes
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Kim H, Kim B, Kim SZ, Cho KW, Kim SH
- KMID: 2147613
- J Korean Ophthalmol Soc.
- 1999 May;40(5):1184-1194.
Atrial natriuretic peptide(ANP), a peptide hormone synthesized mainly in the cardiac atrium, has an important physiological role on the regulation of body fluid and electrolyte balance. Extraatrial ANP system has... -
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- Anticancer Effect of AG60 (Acriflavine-Guanosine Compound) on the Ehrlich Cancer Cells Light Microscopic, Autoradiographic and Electron Microscopic Study
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Ahn ET, Ko JS, Kim HJ, Kim SG, Lee KY, Kang JK, Yoo BI, Chung YS, Hong EK, Han YB
- KMID: 2224573
- Korean J Anat.
- 1999 Apr;32(2):117-134.
To evaluate the effect and working mechanism of a newly developed anti-cancer drug, AG60 (acriflavine-guanosine compound, Taerim Pharm. Co. Seoul, Korea), histotologic, autoradiographic and electron microscopic studies were carried out.... -
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- Autoradiographic Study on the Effect of AG60 to the DNA Synthesis of Gastric Epithelium of Mouse Inoculated with Ehrlich Carcinoma
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Park KH, Ahn ET, Ko JS, Ha SS, Chung YS, Hong EK, Yoo BI, Kim SG, Lee KY, Kang JK, Han YB
- KMID: 2224598
- Korean J Anat.
- 1999 Feb;32(1):95-104.
To study the tumor-suppression effect of a newly developed anti-tumor agent AG60 [acriflavine (1) : guanosine (1) composition, Taerim Pharm. Co., Seoul, Korea], each Ehrlich carcinoma (10(7) cells)-inoculated mouse received... -
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- Biodistribution and Scintigraphy of Iodine-131-Iododeoxyadenosine in Rats Bearing Breast Cancer
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Kim SG, Kim CG, Lee KM, Kim HW, Min BC, Choi SS, Lee JD, Yang DJ, Kim EE, Lee HC, Won JJ
- KMID: 2078714
- Korean J Nucl Med.
- 1998 Aug;32(4):374-381.
PURPOSE: I-131 labeled (2'-deoxy-2-iodo-p-D-arabinofuranosyl) adenine (IAD) may be involved in DNA synthesis during active proliferation of tumor cells. We conducted this study to find out the biodistribution of IAD and... -
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- Autoradiographic Investigation for 3H-Thymidine Labeling Indicies of gamma-Glutamyl Transpeptidase Positive Foci during the Rat Liver Carcinogenesis
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Kweon KW, Kim HJ, Lee SH, Cho YJ, Kim JC, Kim SW, Kim HS, Back IG, Jung CH, Jo YH, Gham CW, Lee DH
- KMID: 2143305
- Korean J Hepatol.
- 1998 Jun;4(2):162-178.
No abstract available. -
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- Ontogeny of Adrenergic Receptors in the Rat Amygdala
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Chung YY, Bae CS
- KMID: 1530112
- Korean J Anat.
- 1998 Jun;31(3):447-463.
The mammalian amygdala comprises a heterogeneous complex of cytoarchitectonically, histochemically and connectionally distinct nuclei. To investigate the developmental changes and regional distributions of adrenoceptor binding sites in the adult and... -
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- The role of adenosine receptors on acetylcholine release in the rat striatum
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Kim DK, Kim HA, Choi BK
- KMID: 2285152
- Korean J Physiol Pharmacol.
- 1997 Feb;1(1):1-12.
As it has been reported that the depolarization induced acetylcholine (ACh) release is modulated by activation of presynaptic A-1 adenosine heteroreceptor and various evidence suggest that indicate the A-2 adenosine receptor is present... -
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- Renin Angiotensin System in Rabbit Corpus Cavernosum: Functional Characterization of Angiotensin II Receptors
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Park JK, Park YK, Kim SZ, Kim SH, Cho KW
- KMID: 1914477
- Korean J Urol.
- 1997 Jan;38(1):28-36.
No abstract available. -
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