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Repeated Morphine Administration Increases TRPV1 mRNA Expression and Autoradiographic Binding at Supraspinal Sites in the Pain Pathway

Nguyen TL, Nam YS, Lee SY, Jang CG

Repeated morphine administration induces tolerance to its analgesic effects. A previous study reported that repeated morphine treatment activates transient receptor potential vanilloid type 1 (TRPV1) expression in the sciatic nerve,...
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Rapid Changes in D1 and D2 Dopamine Receptor Binding in Striatal Subregions after a Single Dose of Phencyclidine

Dalton VS, Zavitsanou K

  • KMID: 2171262
  • Clin Psychopharmacol Neurosci.
  • 2011 Aug;9(2):67-72.
OBJECTIVE: In humans, a single exposure to phencyclidine (PCP) can induce a schizophrenia-like psychosis which can persist for up to two weeks. In rats, an acute dose of PCP increases...
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Feasibility of Reflecting Improvement of Tumor Hypoxia by Mild Hyperthermia in Experimental Mouse Tumors with 18F-Fluoromisonidazole

Lee SW, Ryu JS, Oh SJ, Im KC, Chen GJ, Lee SR, Song DY, Im SJ, Moon ES, Kim JH, Ahn SD, Shin SS, Lee KR, Moon DH, Choi EK

  • KMID: 2198575
  • J Korean Soc Ther Radiol Oncol.
  • 2004 Dec;22(4):288-297.
PURPOSE: The aims of this study were to evaluate the change of [18F]fluoromisonidazole ([18F]FMISO) uptake in C3H mouse squamous cell carcinoma-VII (SCC-VII) treated with mild hyperthermia (42oC) and nicotinamide and...
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Electron Microscopic Autoradiographic Study on the Secretion of Atrial Specific Granules from Atrial Cardiocytes in Dehydrated Rats

Shin HY, Song CH, Kim HT, Han EH, Lim JW, Lee MS

  • KMID: 2224504
  • Korean J Anat.
  • 2004 Jun;37(3):241-253.
This study was performed to investigate for the effect of dehydration on the synthesis, secretion and secreted pathway of atrial specific granules contained ANP by electron microscopic autoradiography. Male Sprague-Dawley...
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The Temporospatial Distribution of Glutamate Receptors and the Effect of MK-801 on Glutamate Receptors Activation in Kainate-induced Seizure Model: Quantitative Receptor Autoradiography of Ionotropic Glutamate Receptors

Kim MK, Kim BC, Sohn EJ, Cho KH, Lee MC

  • KMID: 2342953
  • J Korean Neurol Assoc.
  • 2002 Mar;20(2):179-186.
BACKGROUND: Excitotoxicity and epileptogenesis have often been associated with glutamate receptor activation. Some evidence indicates that selective down regulation of AMPA receptor may be the mechanism of delayed neuronal cell...
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Chromatin Pattern-Dependent mRNA Synthesis in HeLa Cells and HeLa Tumors

Lee JH, Kang MW, Choi C, Juhng SW

  • KMID: 2172398
  • Chonnam Med J.
  • 2001 Dec;37(4):351-356.
Malignant cell nuclei, in general, have increased amount of heterochromatin and decreased electron density of euchromatin, making the chromatin pattern coarser than that of benign cell nuclei. Chromatin pattern in...
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Effects of Bacillus Calmette-Guerin (BCG) on the Spleen of Mouse Inoculated with Ehrlich Carcinoma Cells: A Morphological Study

Ko JS, Park SH, Ahn ET, Park KH, Kim JG

  • KMID: 2092774
  • Korean J Anat.
  • 2001 Oct;34(5):451-465.
This experiment was performed to study the morphological responses of the spleen of mouse inoculated with Ehrlich carcinoma cells, following administration of Bacillus Calmette-Guerin (BCG). Healthy adult ICR mice weighing...
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mRNA is Synthesized Mainly at the Phase between the Euchromatin and Heterochromatin: Proposal of a Phase Theory

Kim MS, Juhng SW

  • KMID: 2275638
  • Korean J Pathol.
  • 2001 Apr;35(2):93-97.
BACKGROUND: Malignant cell nuclei, in general, have increased amounts of heterochromatin and decreased electron densities of euchromatin, making the chromatin pattern coarser than that of benign cell nuclei. The...
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Effects of Lower Dose-Injections of Acriflavine-Guanosine Compound (AG60) on the DNA Synthesis and Ultrastructure of the Ehrlich Carcinoma Cells Inoculated to the Mouse

Ahn ET, Cheong KS, Ko JS, Park KH, Kim JG

  • KMID: 2224527
  • Korean J Anat.
  • 2000 Dec;33(6):651-664.
AG60, a recently introduced anti-cancer compound, was reported to show highly effective anti-cancer activities, when injected with doses from 30 mg/kg to 5 mg/kg.The purpose of this study was to...
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Changes of the level of G protein alpha-subunit mRNA by withdrawal from morphine and butorphanol

Oh S

  • KMID: 1917022
  • Korean J Physiol Pharmacol.
  • 2000 Aug;4(4):291-299.
Morphine or butorphanol was continuously infused into cerebroventricle (i.c.v.) with the rate of 26 nmol/microliter/h for 3 days, and the withdrawal from opioid was rendered 7 hrs after the stopping of infusion....
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Quantitative Autoradiography on Ontogenic Development of alpha-Adrenoceptor in the Rat Cerebral Cortex

Lee MK, Lee SW, Kook JH, Chung YY, Lee EJ, Kim JK, Bae CS

  • KMID: 2092708
  • Korean J Anat.
  • 1999 Oct;32(5):749-760.
Adrenoceptors mediate response to catecholamines throughout the body. To investigate postnatal ontogenic development of alpha1- and alpha2- adrenoceptors in the rat cerebral cortex, in vitro autoradiography was done on frontal,...
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Biodistribution of Iodine-131-Iodomisonidazole and Imaging of Tumor Hypoxia in Mice bearing CT-26 Adenocarcinoma

Kim HW, Kim CG, Yoon KH, Kim HJ, Juhng SK, Roh BS, Yang DJ, Kim EE, Lee HC

  • KMID: 1926584
  • Korean J Nucl Med.
  • 1999 Jun;33(3):289-297.
urpose: Misonidazole is a radiosensitizer that binds in hypoxic cells. The purpose of this study was to find out the feasibility of I-131-Iodomisonidazole (IMISO) for imaging of tumor hypoxia. MATERIALS...
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Atrial Natriuretic Peptide System in Eyes

Kim H, Kim B, Kim SZ, Cho KW, Kim SH

  • KMID: 2147613
  • J Korean Ophthalmol Soc.
  • 1999 May;40(5):1184-1194.
Atrial natriuretic peptide(ANP), a peptide hormone synthesized mainly in the cardiac atrium, has an important physiological role on the regulation of body fluid and electrolyte balance. Extraatrial ANP system has...
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Anticancer Effect of AG60 (Acriflavine-Guanosine Compound) on the Ehrlich Cancer Cells Light Microscopic, Autoradiographic and Electron Microscopic Study

Ahn ET, Ko JS, Kim HJ, Kim SG, Lee KY, Kang JK, Yoo BI, Chung YS, Hong EK, Han YB

  • KMID: 2224573
  • Korean J Anat.
  • 1999 Apr;32(2):117-134.
To evaluate the effect and working mechanism of a newly developed anti-cancer drug, AG60 (acriflavine-guanosine compound, Taerim Pharm. Co. Seoul, Korea), histotologic, autoradiographic and electron microscopic studies were carried out....
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Autoradiographic Study on the Effect of AG60 to the DNA Synthesis of Gastric Epithelium of Mouse Inoculated with Ehrlich Carcinoma

Park KH, Ahn ET, Ko JS, Ha SS, Chung YS, Hong EK, Yoo BI, Kim SG, Lee KY, Kang JK, Han YB

  • KMID: 2224598
  • Korean J Anat.
  • 1999 Feb;32(1):95-104.
To study the tumor-suppression effect of a newly developed anti-tumor agent AG60 [acriflavine (1) : guanosine (1) composition, Taerim Pharm. Co., Seoul, Korea], each Ehrlich carcinoma (10(7) cells)-inoculated mouse received...
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Biodistribution and Scintigraphy of Iodine-131-Iododeoxyadenosine in Rats Bearing Breast Cancer

Kim SG, Kim CG, Lee KM, Kim HW, Min BC, Choi SS, Lee JD, Yang DJ, Kim EE, Lee HC, Won JJ

  • KMID: 2078714
  • Korean J Nucl Med.
  • 1998 Aug;32(4):374-381.
PURPOSE: I-131 labeled (2'-deoxy-2-iodo-p-D-arabinofuranosyl) adenine (IAD) may be involved in DNA synthesis during active proliferation of tumor cells. We conducted this study to find out the biodistribution of IAD and...
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Autoradiographic Investigation for 3H-Thymidine Labeling Indicies of gamma-Glutamyl Transpeptidase Positive Foci during the Rat Liver Carcinogenesis

Kweon KW, Kim HJ, Lee SH, Cho YJ, Kim JC, Kim SW, Kim HS, Back IG, Jung CH, Jo YH, Gham CW, Lee DH

  • KMID: 2143305
  • Korean J Hepatol.
  • 1998 Jun;4(2):162-178.
No abstract available.
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Ontogeny of Adrenergic Receptors in the Rat Amygdala

Chung YY, Bae CS

  • KMID: 1530112
  • Korean J Anat.
  • 1998 Jun;31(3):447-463.
The mammalian amygdala comprises a heterogeneous complex of cytoarchitectonically, histochemically and connectionally distinct nuclei. To investigate the developmental changes and regional distributions of adrenoceptor binding sites in the adult and...
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The role of adenosine receptors on acetylcholine release in the rat striatum

Kim DK, Kim HA, Choi BK

  • KMID: 2285152
  • Korean J Physiol Pharmacol.
  • 1997 Feb;1(1):1-12.
As it has been reported that the depolarization induced acetylcholine (ACh) release is modulated by activation of presynaptic A-1 adenosine heteroreceptor and various evidence suggest that indicate the A-2 adenosine receptor is present...
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Renin Angiotensin System in Rabbit Corpus Cavernosum: Functional Characterization of Angiotensin II Receptors

Park JK, Park YK, Kim SZ, Kim SH, Cho KW

  • KMID: 1914477
  • Korean J Urol.
  • 1997 Jan;38(1):28-36.
No abstract available.
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