- ATP released from beta-amyloid-stimulated microglia induces reactive oxygen species production in an autocrine fashion
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Kim SY, Moon JH, Lee HG, Kim SU, Lee YB
- KMID: 1091077
- Exp Mol Med.
- 2007 Dec;39(6):820-827.
Present study demonstrated that fibrillar beta-amyloid peptide (fAbeta(1-42)) induced ATP release, which in turn activated NADPH oxidase via the P2X(7) receptor (P2X(7)R). Reactive oxygen species (ROS) production in fAbeta(1-42)-treated microglia... -
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