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Association between previous abortion history and risk of autism spectrum disorders among offspring: a meta-analysis

Jenabi E, Ayubi E, Bashirian S, Seyedi M, Rezaei M

Background: Previous studies have been showed an association between previous abortion history and risk of Autism spectrum disorders (ASD). However, there is still controversy about true effect estimate of the...
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Not breastfeeding and risk of autism spectrum disorders among children: a meta-analysis

Jenabi E, Bashirian S, Salehi AM, Khazaei S

Background: To our knowledge, this is the first meta-analysis of the association of not breastfeeding and the risk of autism spectrum disorder (ASD) based on observational studies. Purpose: This meta-analysis aimed...
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Caregiver Burden in Schizophrenia and Autism Spectrum Disorders: A Comparative Study

Yıldız M, Demir Y, Kırcalı A, İncedere A

Objective There is no study comparing schizophrenia and autism spectrum disorders (ASD) in terms of caregiver burden. This study aims to compare the caregiver burden among family members of the...
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An Intervention Program Targeting Daily Adaptive Skills Through Executive Function Training for Adults with Autism Spectrum Disorder: A Pilot Study

Kim JH, Kim YA, Song DY, Cho HB, Lee HB, Park JH, Lim JI, Hong MH, Chae PK, Yoo HJ

Objective Adults with autism spectrum disorders (ASD) experience significant difficulties with executive functioning (EF) and related adaptive skills, yet the lack of interventions in South Korea targeting these areas has...
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Association between pesticide and polychlorinated biphenyl exposure during pregnancy and autism spectrum disorder among children: a meta-analysis

Mehri F, Bashirian S, khazaei S, Jenabi E

Background: The effect of exposure to environmental factors on autism spectrum disorders (ASD), especially during pregnancy, is unclear. Purpose: This meta-analysis investigated the association between exposure to pesticides and polychlorinated...
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State and Trait Anxiety of Adolescents with Autism Spectrum Disorders

Kim SY, Kim YA, Song DY, Bong G, Kim Jm, Kim JH, Yoo HJ

Objective This study examined how state and trait anxiety of adolescents with autism spectrum disorders (ASD) are associated with their demographic characteristics, repetitive and restricted behaviors (RRBs), and internalizing and...
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Evaluation of drug interventions for the treatment of sleep disorders in children with autism spectrum disorders: a systematic review

Jenabi E, Ataei S, Bashirian

A structured review study of drug interventions on sleep disorders in patients with autism spectrum disorders (ASD) has not been published to date. This systematic review aimed to investigate drug...
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Chromosomal Microarray Analysis as a First-Tier Clinical Diagnostic Test in Patients With Developmental Delay/Intellectual Disability, Autism Spectrum Disorders, and Multiple Congenital Anomalies: A Prospective Multicenter Study in Korea

Jang W, Kim Y, Han E, Park J, Chae H, Kwon A, Choi H, Kim J, Son JO, Lee SJ, Hong BY, Jang DH, Han JY, Lee JH, Kim SY, Lee IG, Sung IK, Moon Y, Kim M, Park JH

BACKGROUND: To validate the clinical application of chromosomal microarray analysis (CMA) as a first-tier clinical diagnostic test and to determine the impact of CMA results on patient clinical management, we...
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Empathy Study in Rodent Model of Autism Spectrum Disorders

Mony TJ, Hong M, Lee HJ

There is a highly cognitive and social context to empathy behavior in human. In various social contexts, rodents also display remarkable affective sensitivity and exhibit primitive forms of empathy similar...
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Differences of Obstetric Complications and Clinical Characteristics between Autism Spectrum Disorder and Intellectual Disability

Lee SB, Kim JY, Chung HJ, Kim SW, Im WY, Song JE

OBJECTIVES: Since the awareness of autism spectrum disorders(ASD) is growing, as a result, it is increasing numbers of infants and toddlers being referred to specialized clinics for a differential diagnosis...
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Recent Advances in Autism Spectrum Disorders: Applications of Whole Exome Sequencing Technology

Sener EF, Canatan H, Ozkul Y

Autism spectrum disorders (ASD) is characterized by three core symptoms with impaired reciprocal social interaction and communication, a pattern of repetitive behavior and/or restricted interests in early childhood. The prevalence...
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Clinical and Neurobiological Relevance of Current Animal Models of Autism Spectrum Disorders

Kim KC, Gonzales E, Lázaro MT, Choi CS, Bahn GH, Yoo HJ, Shin CY

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by social and communication impairments, as well as repetitive and restrictive behaviors. The phenotypic heterogeneity of ASD has made it overwhelmingly...
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Routine Chromosomal Microarray Analysis is Necessary in Korean Patients With Unexplained Developmental Delay/Mental Retardation/Autism Spectrum Disorder

Shin S, Yu N, Choi JR, Jeong S, Lee KA

BACKGROUND: All over the world, chromosomal microarray (CMA) is now the first tier diagnostic assay for genetic testing to evaluate developmental delay (DD), mental retardation (MR), and autism spectrum disorder...
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A Randomized, Placebo-controlled Trial of Digestive Enzymes in Children with Autism Spectrum Disorders

Saad K, Eltayeb AA, Mohamad IL, Al-Atram A, Elserogy Y, Bjorklund , El-Houfey , Nicholson

OBJECTIVE: There is growing evidence for a gut-brain connection associated with autism spectrum disorders (ASDs). This suggests a potential benefit from introduced digestive enzymes for children with ASD. METHODS: We performed...
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Clinical Characteristics According to the Presence of Restricted, Repetitive Behaviors and Interests in Children with High Functioning Autism Spectrum Disorder

Lee S, Lee KM, Yoo HJ

OBJECTIVES: The objective of this study was to investigate the relationship between restricted, repetitive behaviors and interests (RRBI) and autistic symptoms in Korean high functioning autism spectrum disorder (ASD) children...
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Polymorphisms of BDNF Gene and Autism Spectrum Disorders: Family Based Association Study with Korean Trios

Yoo HJ, Yang SY, Cho IH, Park M, Kim SA

  • KMID: 2316354
  • Psychiatry Investig.
  • 2014 Jul;11(3):319-324.
OBJECTIVE: Autism spectrum disorders (ASDs) are a group of early childhood-onset neurodevelopmental disorders characterized by deficits in social interaction and language skills, and repetitive behaviors. Brain-derived neurotrophic factor (BDNF) plays...
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A Comparison Study of Clinical Characteristics in Adolescents with Autism Spectrum Disorder without and with Attention-Deficit Hyperactivity Disorder

Song JW, Bahn GH, Cho IH, Cho SC, Kim BN, Shin MS, Kim JW, Park S, Hong SB, Yoo HJ

  • KMID: 2291618
  • J Korean Acad Child Adolesc Psychiatry.
  • 2013 Dec;24(4):213-219.
OBJECTIVES: It is known that adolescents with autism spectrum disorder (ASD) often concurrently exhibit attention-deficit hyperactivity disorder (ADHD). The objective of this study is to investigate how ADHD symptoms modify...
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Association of the Catechol-o-Methyltransferase Gene Polymorphisms with Korean Autism Spectrum Disorders

Yoo HJ, Cho IH, Park M, Yang SY, Kim SA

This study evaluated the family-based genetic association between autism spectrum disorders (ASDs) and 5 single-nucleotide polymorphisms (SNPs) in the catechol-o-methyltransferase gene (COMT), which was found among 151 Korean ASDs family...
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No Association between Single Nucleotide Polymorphisms in Urocanase Domain Containing 1 (UROC1) and Autism Spectrum Disorders (ASDs) in the Korean Population

Park J, Ro M, Nam M, Bang HJ, Yang JW, Choi KS, Kim SK, Chung JH, Kwack K

  • KMID: 2291656
  • J Korean Acad Child Adolesc Psychiatry.
  • 2012 Mar;23(1):8-13.
OBJECTIVES: Urocanase domain containing 1 (UROC1) has never been studied in prior studies on autism spectrum disorders (ASDs). UROC1 causes urocanic aciduria, one of the symptoms of which is mental...
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Clinical Characteristics of Developmental Regression in Autism Spectrum Disorders

Kim JS, Yoo HJ, Cho IH, Park TW, Son JW, Chung US, Shin MS, Kim BN, Kim JW, Yang YH, Kang JW, Song SH, Cho SC

  • KMID: 2291672
  • J Korean Acad Child Adolesc Psychiatry.
  • 2011 Sep;22(3):141-148.
OBJECTIVE: A significant proportion of children with autism spectrum disorders (ASD) have regression characterized by loss of previously acquired skills. The purpose of this study was to compare demographic, clinical...
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