- Attenuation of airway inflammation by simvastatin and the implications for asthma treatment: is the jury still out?
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Liu JN, Suh DH, Yang EM, Lee SI, Park HS, Shin YS
- KMID: 2155378
- Exp Mol Med.
- 2014 Sep;46(9):e113.
- doi: 10.1038/emm.2014.55
Although some studies have explained the immunomodulatory effects of statins, the exact mechanisms and the therapeutic significance of these molecules remain to be elucidated. This study not only evaluated the... -
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- An antioxidant modulates expression of receptor activator of NF-kappaB in asthma
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Lee KS, Park HS, Park SJ, Kim SR, Min KH, Jin SM, Li L, Lee YC
- KMID: 1094147
- Exp Mol Med.
- 2006 Jun;38(3):217-229.
Oxidative stress plays critical roles in airway inflammation that is usually accompanied by increased vascular permeability and plasma exudation. VEGF increases vascular permeability and leads to airway inflammation. In addition,... -
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