- Clinical and Radiological Features of Korean Patients With Anti-HMGCR Myopathy
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Oh EK, Lee SA, Lee HJ, Cha YJ, Kim S, Lee HS, Suh BC, Shin HY, Kim SW, Yoon BA, Oh Si, Kim YH, Cho JY, Cho JH, Kwon KH, Choi YC, Park HJ
- KMID: 2545499
- J Clin Neurol.
- 2023 Sep;19(5):460-468.
- doi: 10.3988/jcn.2022.0374
Background and Purpose To understand the characteristics of Korean patients with anti-3-hydroxy-3-methylglutaryl-coenxyme A reductase (HMGCR) myopathy, we measured antiHMGCR antibodies and analyzed the clinical, radiological, and pathological features of patients... -
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- Facile Titrimetric Assay of Lysophosphatidic Acid in Human Serum and Plasma for Ovarian Cancer Detection
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Tarannum N, Kumar D, Agrawal R
- KMID: 2544344
- J Cancer Prev.
- 2023 Jun;28(2):31-39.
- doi: 10.15430/JCP.2023.28.2.31
Herein, an instrument free facile acid-base titrimetric methodology is reported for lysophosphatidic acid (LPA) measurement in serum and plasma samples for ovarian cancer detection. The concept is based on the... -
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- Prevalence of bovine viral diarrhea virus from Korean native cattle farms in Jeju
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Cho SC, Yang HS, Park C, Kim ST, Ko EJ, Son WG
- KMID: 2543759
- Korean J Vet Res.
- 2023 Jun;63(2):e12.
- doi: 10.14405/kjvr.20230001
Bovine viral diarrhea virus (BVDV) is an RNA virus belonging to Pestivirus in the family Flaviviridae. BVDV has economic significance for the livestock industry because of its association with acute... -
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- Measurement of serum anti-Müllerian hormone by revised Gen II or automated assay: Reproducibility under various blood/serum storage conditions
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Lee JY, Kim CH, Choe SA, Seo S, Kim SH
- KMID: 2542570
- Clin Exp Reprod Med.
- 2023 Jun;50(2):107-116.
- doi: 10.5653/cerm.2022.05687
Objective: We investigated the agreement between anti-Müllerian hormone (AMH) levels measured with revised Gen II (rev-Gen II) and automated AMH (Access) assays and evaluated the reproducibility of each method under... -
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- Therapeutic effects of paeoniflorin on irritable bowel syndrome in rats
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Wang L, Lei J, Zhao Z, Jia J, Wang L
- KMID: 2542986
- J Vet Sci.
- 2023 May;24(3):e23.
- doi: 10.4142/jvs.22083
Background: Irritable bowel syndrome (IBS) is a functional bowel disorder (FBD). Objectives: To assess the therapeutic effects of paeoniflorin (PF) on IBS in rats. Method: Sixty male Sprague–Dawley rats were randomly divided... -
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- A Neuroprotective Action of Quercetin and Apigenin through Inhibiting Aggregation of Aβ and Activation of TRKB Signaling in a Cellular Experiment
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Chiu YJ, Teng YS, Chen CM, Sun YC, Hsieh-Li HM, Chang KH, Lee-Chen GJ
- KMID: 2541787
- Biomol Ther.
- 2023 May;31(3):285-297.
- doi: 10.4062/biomolther.2022.136
Alzheimer’s disease (AD) is a neurodegenerative disease with progressive memory loss and the cognitive decline. AD is mainly caused by abnormal accumulation of misfolded amyloid β (Aβ), which leads to... -
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- A Survey on Antinuclear Antibodies Testing in Korea
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Kim KH
- KMID: 2541074
- Lab Med Qual Assur.
- 2023 Mar;45(1):29-33.
- doi: 10.15263/jlmqa.2023.45.1.29
Background: Antinuclear antibodies (ANA) detected by indirect immuno fluorescence assay (IFA) on HEp-2 cells are important for the diagnosis of systemic rheumatic diseases. ANA is an entry criterion in the... -
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- Development and Application of a Cell-Based Assay for LRP4 Antibody Associated With Myasthenia Gravis
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Chung HY, Kim MJ, Kim SW, Oh J, Shin HY
- KMID: 2537185
- J Clin Neurol.
- 2023 Jan;19(1):60-66.
- doi: 10.3988/jcn.2023.19.1.60
Background and Purpose Among patients with double-seronegative myasthenia gravis (dSN-MG) who do not have detectable antibodies against acetylcholine receptor or musclespecific tyrosine kinase, autoantibodies against low-density lipoprotein receptor-related protein 4... -
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- A standardized method to study immune responses using porcine whole blood
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Mattoo SuS, Aganja RP, Kim SC, Jeong CG, Nazki S, Khatun A, Kim WI, Lee SM
- KMID: 2539431
- J Vet Sci.
- 2023 Jan;24(1):e11.
- doi: 10.4142/jvs.22210
Background: Peripheral blood mononuclear cells (PBMCs) are commonly used to assess in vitro immune responses. However, PBMC isolation is a time-consuming procedure, introduces technical variability, and requires a relatively large... -
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- Virtual Screening and Testing of GSK-3 Inhibitors Using Human SH-SY5Y Cells Expressing Tau Folding Reporter and Mouse Hippocampal Primary Culture under Tau Cytotoxicity
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Lin CH, Hsieh YS, Sun YC, Huang WH, Chen SL, Weng ZK, Lin TH, Wu YR, Chang KH, Huang HJ, Lee GC, Hsieh-Li HM, Lee-Chen GJ
- KMID: 2537589
- Biomol Ther.
- 2023 Jan;31(1):127-138.
- doi: 10.4062/biomolther.2022.035
Glycogen synthase kinase-3β (GSK-3β) is an important serine/threonine kinase that implicates in multiple cellular processes and links with the neurodegenerative diseases including Alzheimer’s disease (AD). In this study, structure-based virtual... -
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- Interlaboratory Comparison Study (Ring Test) of Next-Generation Sequencing–Based NTRK Fusion Detection in South Korea
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Lee SE, Lee MS, Jeon YK, Shim HS, Kang J, Kim J, Choi YL
- KMID: 2537989
- Cancer Res Treat.
- 2023 Jan;55(1):28-40.
- doi: 10.4143/crt.2021.1572
Purpose Tropomyosin receptor kinase (TRK) inhibitors are approved for the treatment of neurotrophic receptor tyrosine kinase (NTRK) fusion-positive tumors. The detection of NTRK fusion using a validated method is required... -
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- Allergic Sensitization Pattern in the Korean Dermatologic Patients
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Han Y, Woo YR, Kim HS, Lee JD, Choi S, Yu J, Cho SH
- KMID: 2536302
- Ann Dermatol.
- 2022 Dec;34(6):431-441.
- doi: 10.5021/ad.21.260
Background: Avoiding causative allergens is important for controlling the clinical course of allergic diseases. Allergen sensitization is influenced by many factors including the environment and lifestyle. The socioeconomic development, climate,... -
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- Genotoxicity study of 2-methoxyethanol and benzalkonium chloride through Comet assay using 3D cultured HepG2 cells
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Lim C, Shin K, Seo D
- KMID: 2539835
- Environ Anal Health Toxicol.
- 2022 Dec;37(4):e2022031.
- doi: 10.5620/eaht.2022031
Though the key data in identifying carcinogenicity is experience in human, long-term carcinogenicity tests using experimental animals are more realistic. Because carcinogenicity tests require much time and cost, performing the... -
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- Re-Cellularised Kidney Scaffold for Chikungunya Virus Propagation: A Novel Approach
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Walawalkar S, Almelkar S
- KMID: 2533914
- Tissue Eng Regen Med.
- 2022 Aug;19(4):769-779.
- doi: 10.1007/s13770-022-00449-1
BACKGROUND: Re-emerging viral attacks are catastrophic for health and economy. It is crucial to grasp the viral life cycle, replication and mutation policies and attack strategies. It is also absolute... -
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- Evaluation of the Xpert Carba-R Assay for Detection of Rectal Carbapenemase-producing Enterobacterales in a Korean Tertiary Hospital
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Han J, Ha SI, Shin DP, Cha YJ, Yoo IY, Park YJ
- KMID: 2538602
- Lab Med Online.
- 2022 Jul;12(3):175-182.
- doi: 10.47429/lmo.2022.12.3.175
Background: Carbapenemase-producing Enterobacterales (CPE) have been highlighted as an urgent threat by international health authorities. Rapid detection of carbapenemase will allow implementation of infection control measures. Methods: We assessed the performance... -
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- Applying Functional Assay Evidence to Interpret Sequence Variants Identified in Hereditary Cancer Genes
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Choi YJ, Kim B, Kim Y, Shin S, Lee KA
- KMID: 2538599
- Lab Med Online.
- 2022 Jul;12(3):145-158.
- doi: 10.47429/lmo.2022.12.3.145
The demand for the interpretation of sequence variants identified by next-generation sequencing is gradually increasing in clinical laboratories. The American College of Medical Genetics and the Association for Molecular Pathology... -
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- Commutability Assessment of Frozen Human Serum Pools for External Quality Assessment of Tumor Markers
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Cho Ej, Kim SH, Hong J, Lee H, Hyun J, Cho SE, Lee W, Kim HS, Oh EJ, Chun S, Min WK
- KMID: 2531129
- Lab Med Qual Assur.
- 2022 Jun;44(2):111-120.
- doi: 10.15263/jlmqa.2022.44.2.111
Background: Commutability is essential to harmonize different measuring systems and to evaluate the performance of participating laboratories in external quality assessment (EQA). This study aims to assess the com mutability... -
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- Chemical Profile and Cytotoxicity Activity of Stem-bark of Anacardium occidentale
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Shehu A, Ponnapalli MG, Mahboob M, Prabhakar PV, Olatunji GA
- KMID: 2530933
- Nat Prod Sci.
- 2022 Jun;28(2):62-67.
- doi: 10.20307/nps.2022.28.2.62
Column chromatographic fractionation of the methanol and ethyl acetate extracts of the stem-bark of Anacardium occidentale led to the isolation of five compounds (1-5). Their structures were determined by spectroscopic... -
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- The relationship between reactive oxygen species, DNA fragmentation, and sperm parameters in human sperm using simplified sucrose vitrification with or without triple antioxidant supplementation
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Juanpanich T, Suttirojpattana T, Parnpai R, Vutyavanich T
- KMID: 2531713
- Clin Exp Reprod Med.
- 2022 Jun;49(2):117-126.
- doi: 10.5653/cerm.2021.05120
Objective: This study examined whether the addition of triple antioxidants (3A)—10 μM acetyl-L-carnitine, 10 μM N-acetyl-L-cysteine, and 5 μM α-lipoic acid—in freezing-thawing medium during human sperm cryopreservation using the sucrose... -
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- A combined application of molecular docking technology and indirect ELISA for the serodiagnosis of bovine tuberculosis
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Song S, Zhang Q, Yang H, Guo J, Xu M, Yang N, Yi J, Wang Z, Chen C
- KMID: 2530443
- J Vet Sci.
- 2022 May;23(3):e50.
- doi: 10.4142/jvs.21270
Background: There is an urgent need to find reliable and rapid bovine tuberculosis (bTB) diagnostics in response to the rising prevalence of bTB worldwide. Toll-like receptor 2 (TLR2) recognizes components... -
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