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Association Between Cadmium Exposure and Liver Function in Adults in the United States: A Cross-sectional Study

Hong D, Min JY, Min KB

Objectives: Cadmium is widely used, leading to extensive environmental and occupational exposure. Unlike other organs, for which the harmful and carcinogenic effects of cadmium have been established, the hepatotoxicity of...
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Increased Visit-to-Visit Liver Enzyme Variability Is Associated with Incident Diabetes: A Community-Based 12-Year Prospective Cohort Study

Bang K, Jun JE, Jeong IK, Ahn KJ, Chung HY, Hwang YC

Background: Fatty liver and/or increased liver enzyme values have been reported to be associated with incident diabetes. We sought to determine whether increased visit-to-visit liver enzyme variability is associated with...
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Association between extract from fruit of Opuntia ficus-indica and streptozotocin-induced diabetic rats

Jo H, Kim HS, Kim DJ, Sim SB

Opuntia ficus-indica has traditionally been used in prevention and treatment of various diseases such as diabetes mellitus. The current study was performed to determine whether Opuntia ficus-indica is associated with...
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Liver Enzymes and Risk of Stroke: The Atherosclerosis Risk in Communities (ARIC) Study

Ruban A, Daya N, Schneider AL, Gottesman R, Selvin E, Coresh J, Lazo M, Koton S

Background and Purpose Liver enzymes (aspartate aminotransferase [AST], alanine aminotransferase [ALT], and gamma-glutamyl transpeptidase [GGT]) are glutamate-regulatory enzymes, and higher glutamate levels correlated with worse prognosis of patients with neurotrauma....
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Liver enzyme elevation in patients with ankylosing spondylitis treated with tumor necrosis factor inhibitors: a single-center historical cohort study

Choi SJ, Oh JS, Hong S, Lee CK, Yoo B, Kim YG

Background/Aims: Tumor necrosis factor inhibitors (TNFi) have been known to induce liver enzyme elevation, sometimes associated with viral reactivation or toxic hepatitis. We evaluated the incidence and risk factors of...
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Serum Aminotransferase Level in Rhabdomyolysis according to Concurrent Liver Disease

Jo KM, Heo NY, Park SH, Moon YS, Kim TO, Park J, Choi JH, Park YE, Lee J

BACKGROUND/AIMS: The serum aminotransferase level is usually elevated in rhabdomyolysis, and these enzymes originate from the skeletal muscle. On the other hand, there is limited data showing whether the degree...
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Impact of increased aspartate aminotransferase to alanine aminotransferase (De Ritis) ratio in prognosis of testicular cancer

Gorgel SN, Akin Y, Koc EM, Kose O, Ozcan S, Yilmaz Y

PURPOSE: Imaging studies can show metastasis in testicular cancer (TCa); however, a test for risk of metastasis in TCa has not been described. The ratio of aspartate aminotransferase to alanine...
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Oxidative stress and hepatic injury induced in mice fed a Sarcocystis hirsuta cyst extract

Sasani M, Nabavi R, Hajinezhad M, Hasanein P

We studied the toxic effects of a Sarcocystis hirsuta cyst extract fed to mice. Degenerative changes were found in mice gavage-fed fresh, frozen, and heat-treated S. hirsuta cyst extract. There...
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Mercury Exposure in Association With Decrease of Liver Function in Adults: A Longitudinal Study

Choi J, Bae S, Lim H, Lim JA, Lee YH, Ha M, Kwon HJ

OBJECTIVES: Although mercury (Hg) exposure is known to be neurotoxic in humans, its effects on liver function have been less often reported. The aim of this study was to investigate...
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Effects of Pyridoxal-5'-Phosphate on Aminotransferase Activity Assay

Lee JS, Lee K, Kim SM, Choi MS, Jun SH, Song WH, Song SH, Park KU, Song J

BACKGROUND: Pyridoxal-5'-phosphate (P5P), a coenzyme of the aspartate aminotransferase (AST) and alanine aminotransferase (ALT) reactions, is required to measure aminotransferase levels (IFCC method). However, a modified IFCC method that uses...
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The Independent Effects of Cigarette Smoking, Alcohol Consumption, and Serum Aspartate Aminotransferase on the Alanine Aminotransferase Ratio in Korean Men for the Risk for Esophageal Cancer

Kimm H, Kim S, Jee SH

PURPOSE: The goal of this study is to assess the interactions among alcohol consumption, cigarette smoking, and aspartate aminotransferase (AST) / alanine aminotransferase (ALT) ratios on esophageal cancer. MATERIALS AND...
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Usefulness of Serum alpha-fetoprotein (AFP) as a Marker for Hepatocellular Carcinoma (HCC) in Hepatitis C Virus Related Cirrhosis: Analysis of the Factors Influencing AFP Elevation without HCC Development

Kim KA, Lee JS, Jung ES, Kim JY, Bae WK, Kim NH, Moon YS

  • KMID: 1113479
  • Korean J Gastroenterol.
  • 2006 Nov;48(5):321-326.
BACKGROUND/AIMS: Serum alpha-fetoprotein (AFP) is frequently used for the diagnosis of hepatocellular carcinoma (HCC). Most available data concerning AFP came from studies of patients with chronic hepatitis B or...
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