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Expression of p53 protein in rheumatoid arthritis synovium. An immunohistochemical analysis

Lee YH, Ji JD, Kim A, Kim CH, Song GG

  • KMID: 759085
  • Korean J Intern Med.
  • 1999 Jan;14(1):59-65.
OBJECTIVES: Mutation of p53 may play a role in manifestation of rheumatoid arthritis synovium, but several studies on p53 expression in synovial tissues of rheumatoid arthritis showed conflicting...
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Study on the Fractionation of Synovial Fluid Protein

Kim WJ, Ahn YS, Kim SJ, Jahng JS, Hong SS

Fractionation of protein components of the human synovial fluid was carried out with paper and disc electrophoresis, and isoelectric focusing. The mean ranges of total protein content of synovial fluid...
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Nuclear factor kappaB (NF-kappaB) pathway as a therapeutic target in rheumatoid arthritis

Jue DM, Jeon KI, Jeong JY

Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by persistent joint swelling and progressive destruction of cartilage and bone. Current RA treatments are largely empirical in origin and their...
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Correlation of hand bone mineral density with the metacarpal cortical index and carpo:metacarpal ratio in patients with rheumatoid arthritis

Ozgocmen S, Karaoglan , Kocakoc E, Ardicoglu , Yorgancioglu ZR

This study proposed an assessment of the correlation of hand bone mineral density measured by dual energy x-ray absorbtiometry (DXA) with the carpo:metacarpal (C:MC) ratio and metacarpal cortical index (CI)...
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Synergy between adiponectin and interleukin-1beta on the expression of interleukin-6, interleukin-8, and cyclooxygenase-2 in fibroblast-like synoviocytes

Lee YA, Choi HM, Lee SH, Yang HI, Yoo MC, Hong SJ, Kim KS

  • KMID: 1397448
  • Exp Mol Med.
  • 2012 Jul;44(7):440-447.
To determine whether adiponectin may have synergistic effects in combination with the proinflammatory cytokine interleukin (IL)-1beta regarding the production of proinflammatory mediators during arthritic joint inflammation, synovial cells from rheumatoid...
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The role of adiponectin in the production of IL-6, IL-8, VEGF and MMPs in human endothelial cells and osteoblasts: implications for arthritic joints

Lee YA, Ji HI, Lee SH, Hong SJ, Yang HI, Chul Yoo M, Kim KS

This study was performed to evaluate the contribution of adiponectin to the production of interleukin (IL)-6, IL-8, vascular endothelial growth factor (VEGF), matrix metalloproteinase (MMP)-1 and MMP-13 in human endothelial...
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15-Deoxy-delta12,14-PGJ2inhibits IL-6-induced Stat3 phosphorylation in lymphocytes

Kim HJ, Rho YH, Choi SJ, Lee YH, Cheon HJ, Um JW, Sohn J, Song GG, Ji JD

  • KMID: 1056229
  • Exp Mol Med.
  • 2005 Jun;37(3):179-185.
15-deoxy-delta12,14-PGJ2(15d-PGJ2) is a natural ligand that activates the peroxisome proliferators-activated receptor (PPAR) gamma, a member of nuclear receptor family implicated in regulation of lipid metabolism and adipocyte differentiation. Recent studies...
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