- Lessons for the pathogenesis of rheumatoid arthritis acquired from experimental animal models
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Youn J
- KMID: 2168062
- Hanyang Med Rev.
- 2005 May;25(2):53-66.
Rheumatoid arthritis, a common human disease with a prevalence of about 1%, is characterized by inflammatory autoimmune responses. However, the etiopathogenesis of rheumatoid arthritis is still incompletely understood. A variety... -
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- The effect of medicinal herb administration to arthritis inducded rabbit arthritistreatment
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Kwon TD, Kim KH
- KMID: 2268738
- Korean J Nutr.
- 2012 Oct;45(5):437-442.
- doi: 10.4163/kjn.2012.45.5.437
The purpose of this study was is to investigate the arthritis treatment and prevention of the effects the herbral administration to experimental animals induces arthritis 4 weeks for medicinal herbs... -
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- Experimental Animal Models for Rheumatoid Arthritis: Methods and Applications
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Kim HO, Lee SI
- KMID: 2223070
- J Rheum Dis.
- 2012 Aug;19(4):189-195.
- doi: 10.4078/jrd.2012.19.4.189
Rheumatoid arthritis (RA) is a chronic inflammatory disorder characterized by synovitis and joint damage. The etiology of RA is multi-factorial including various genetic and environmental factors, and the pathogenesis is... -
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- Type II collagen-induced arthritis in rat: changes of IgG anticolla- gen antibody
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Park DJ, Cho CS, Kim HY, Kim DJ
- KMID: 1697975
- Korean J Intern Med.
- 1991 Sep;41(3):423-428.
No abstract available. -
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- Prophylactic effect of plaster and cataplasm contained ketoprofen in rats with adjuvant arthritis
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Kang SS, Choi SH
- KMID: 1103509
- J Vet Sci.
- 2001 Apr;2(1):65-70.
This study demonstrates that prophylactic effect of plaster and cataplasm contained ketoprofen in adjuvant arthritis therapy by X-ray. Adjuvant arthritis was induced by a single injection of Freund's complete adjuvant.... -
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- The Expression of Toll-like Receptors in Collagen-induced Arthritis
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Lee JH, Lee SB, Kim GT, Ryu S, Kim JI, Lee SH, Kim SI
- KMID: 1581087
- J Korean Rheum Assoc.
- 2006 Jun;13(2):140-149.
OBJECTIVE: To evaluate the expression of Toll-like receptor (TLR) 2, 4 and 9 and investigate the effects of IL-17 on the expression of TLRs in experimental rheumatoid arthritis (RA) model. METHODS:... -
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- Effect of a Flavon Extracted from Artemisia absinthium on Collagen Induced Arthritis in Mice
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Choi KM, Hwang DH, Shin KM, Yoon DY, Kim DS
- KMID: 1654903
- Korean J Pediatr.
- 2004 Jun;47(6):677-684.
PURPOSE: In this study, a possible suppressive effect of a flavon extracted from Artemisia absinthium on a mouse collagen-induced arthritis (CIA) model was investigated. METHODS: DBA/1 mice were injected intradermally with... -
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- The Effect of Long Chain N-3 Polyunsaturated Fatty Acids on Development of Collagen-induced Arthritis in Rats
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Shin KH, Kim SD, Jeon HJ, Jang EC, Lee SK
- KMID: 1909945
- Yeungnam Univ J Med.
- 2002 Jun;19(1):39-48.
- doi: 10.12701/yujm.2002.19.1.39
BACKGROUND: The treatment of rheumatoid arthritis still depend on conserve therapy in major. Recent studies report that n-3 polyunsaturated fatty acids(PUFA) could modulate the incidence and progress of arthritis. The... -
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- Effect of Interleukin-10 on Development of Murine Collagen-induced Arthritis
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Yoo B, Kim C, Choi SW, Kim MJ, Oh SW, Moon HB
- KMID: 2025518
- J Korean Rheum Assoc.
- 1997 Jul;4(2):111-120.
OBJECTIVE: To evaluate the effect of IL-10 on development of collagen-induced arthritis, on humoral and cellular immunity and on the endogenous production of IL-10 in DBA/1J mice. METHODS: DBA/1J mice... -
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- Long-term Treatment with Anti-platelet Agents for Collagen-induced Arthritis Improves Radiological Findings
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Kim C, Kim T, Yoo J, Sheen DH, Lee SK, Choi EH, Chun TJ, Kang SW, Shim SC, Lim MK
- KMID: 2394472
- Osong Public Health Res Perspect.
- 2017 Jun;8(3):179-184.
- doi: 10.24171/j.phrp.2017.8.3.04
OBJECTIVES: The objectives of this study were to evaluate the long-term effect of anti-platelet treatment on the radiological progression of collagen-induced arthritis in rats. METHODS: Female Lewis rats with collagen-induced arthritis... -
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- TGF-beta-treated antigen presenting cells suppress collagen-induced arthritis through the promotion of Th2 responses
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Jung S, Park YK, Lee H, Shin JH, Lee GR, Park SH
- KMID: 946651
- Exp Mol Med.
- 2010 Mar;42(3):187-194.
- doi: 10.3858/emm.2010.42.3.019
Collagen-induced arthritis (CIA) is mediated by self-reactive CD4+ T cells that produce inflammatory cytokines. TGF-beta2-treated tolerogenic antigen-presenting cells (Tol-APCs) are known to induce tolerance in various autoimmune diseases. In this... -
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- Grape seed proanthocyanidin extract ameliorates murine autoimmune arthritis through regulation of TLR4/MyD88/NF-κB signaling pathway
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Kim SH, Bang J, Son CN, Baek WK, Kim JM
- KMID: 2411590
- Korean J Intern Med.
- 2018 May;33(3):612-621.
- doi: 10.3904/kjim.2016.053
BACKGROUND/AIMS: Grape seed proanthocyanidin extract (GSPE) has been reported to have a beneficial effect on regulating inf lammation. However, the anti-inflammatory mechanism of GSPE remains unclear. The aim of this... -
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- Over-expression of extracellular superoxide dismutase in mouse synovial tissue attenuates the inflammatory arthritis
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Yu DH, Yi JK, Yuh HS, Park SJ, Kim HJ, Bae KB, Ji YR, Kim NR, Park SJ, Kim DH, Kim SH, Kim MO, Lee JW, Ryoo ZY
- KMID: 1389732
- Exp Mol Med.
- 2012 Sep;44(9):529-535.
Oxidative stress such as reactive oxygen species (ROS) within the inflamed joint have been indicated as being involved as inflammatory mediators in the induction of arthritis. Correlations between extracellular-superoxide dismutase... -
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- Dynamic Frequency of Blood CD4+CD25+ Regulatory T Cells in Rats with Collagen-induced Arthritis
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Wang T, Li J, Jin Z, Wu F, Li Y, Wang X, Zhou H, Zhou Q
- KMID: 2285558
- Korean J Physiol Pharmacol.
- 2015 Mar;19(2):83-88.
- doi: 10.4196/kjpp.2015.19.2.83
CD4+CD25+ regulatory T cells (CD4+CD25+ Tregs) have been shown to play a regulatory or suppressive role in the immune response and are possibly relevant to the pathogenesis of autoimmune diseases.... -
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- Synovial RANKL/OPG mRNA Ratio and Effect of IL-17 in Experimental Rheumatoid Arthritis Model
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Lee JH, Kim GT, Ryu S, Kim JI, Baek SH, Kim SI
- KMID: 1581082
- J Korean Rheum Assoc.
- 2006 Jun;13(2):123-131.
OBJECTIVE: To investigate the synovial mRNA expression of receptor activator of NFkappaB (RANK), RANK ligand (RANKL), osteoprotegerin (OPG) and RANKL/OPG mRNA expression ratio, and to evaluate the effects of IL-17... -
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- Obesity aggravates the joint inflammation in a collagen-induced arthritis model through deviation to Th17 differentiation
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Jhun JY, Yoon BY, Park MK, Oh HJ, Byun JK, Lee SY, Min JK, Park SH, Kim HY, Cho ML
- KMID: 1397446
- Exp Mol Med.
- 2012 Jul;44(7):424-431.
White fat cells secrete adipokines that induce inflammation and obesity has been reported to be characterized by high serum levels of inflammatory cytokines such as IL-6 and TNF-alpha. Rheumatoid arthritis... -
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- Micro-computed tomography evaluation and pathological analyses of female rats with collagen-induced arthritis
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Kim YH, Kang JS
- KMID: 2164525
- J Vet Sci.
- 2015 Jun;16(2):165-171.
- doi: 10.4142/jvs.2015.16.2.165
Imaging techniques have been introduced to assess the efficacy and toxicity of developing pharmaceuticals. The purpose of this study was to perform a comprehensive characterization of collagen-induced arthritis (CIA) in... -
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- Expression of Pain Receptors by Arthritis Treatment in Collagen Induced Murine Model of Rheumatoid Arthritis
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Bang J, Ha E, Hur J
- KMID: 2222910
- J Rheum Dis.
- 2015 Apr;22(2):85-92.
- doi: 10.4078/jrd.2015.22.2.85
OBJECTIVE: Rheumatoid arthritis, the most common form of arthritis, is typically characterized by induced inflammatory pain in joints. Recent studies have reported on the expression of pain receptors such as... -
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- Metformin ameliorates experimental-obesity-associated autoimmune arthritis by inducing FGF21 expression and brown adipocyte differentiation
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Kim EK, Lee SH, Lee SY, Kim JK, Jhun JY, Na HS, Kim SY, Choi JY, Yang CW, Park SH, Cho ML
- KMID: 2438362
- Exp Mol Med.
- 2018 Jan;50(1):e432.
- doi: 10.1038/emm.2017.245
Rheumatoid arthritis (RA) is a systemic autoimmune disease involving excessive inflammation. Recently, RA associated with a metabolic disorder was revealed to be non-responsive to RA medications. Metformin has been reported... -
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- The requirement of natural killer T-cells in tolerogenic APCs-mediated suppression of collagen-induced arthritis
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Jung S, Park YK, Shin JH, Lee H, Kim SY, Lee GR, Park SH
- KMID: 1104381
- Exp Mol Med.
- 2010 Aug;42(8):547-554.
- doi: 10.3858/emm.2010.42.8.055
TGF-beta-induced tolerogenic-antigen presenting cells (Tol-APCs) could induce suppression of autoimmune diseases such as collagen-induced arthritis (CIA) and allergic asthma. In contrast, many studies have shown that NKT cells are involved... -
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