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Cap-independent protein translation is initially responsible for 4-(N-methylnitrosamino)-1-(3-pyridyl)-butanone (NNK)-induced apoptosis in normal human bronchial pithelial cells

Moon SH, Kim HW, Kim JS, Park JH, Kim H, Eu GJ, Cho HS, Kang GM, Lee KH, Cho MH

  • KMID: 1093633
  • J Vet Sci.
  • 2004 Dec;5(4):369-378.
Evidences show that eukaryotic mRNAs can perform protein translation through internal ribosome entry sites (IRES). 5'-Untranslated region of the mRNA encoding apoptotic protease-activating factor 1 (Apaf-1) contains IRES, and, thus,...
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