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Therapeutic Modulation of Apoptosis: Targeting the BCL-2 Family at the Interface of the Mitochondrial Membrane

Nemec KN, Khaled AR

A vast portion of human disease results when the process of apoptosis is defective. Disorders resulting from inappropriate cell death range from autoimmune and neurodegenerative conditions to heart disease. Conversely,...
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Erratum: The Effect of Lowering the Threshold for Diagnosis of Impaired Fasting Glucose

Kim SH, Shim WS, Kim EA, Kim EJ, Lee SH, Hong SB, Kim YS, Park SG, Leem JH, Lee HJ, Nam M

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Apoptosis, bcl2 expression, and cell cycle analyses in nickel(II)-treated normal rat kidney cells

Lee SH, Choi JG, Cho MH

Nickel compounds are carcinogenic to human and are potent inducers of kidney and lung tumors in experimental animals. In this study, the effects of nickel(II) acetate on apoptosis, cell cycle...
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Human Brain Astrocytes Mediate TRAIL-mediated Apoptosis after Treatment with IFN-gamma

Lee J, Shin JS, Choi IH

TNF-related apoptosis inducing ligand (TRAIL) expressions were studied in primary human brain astrocytes in response to pro-inflammatory cytokines. When astrocytes were treated with IL-1beta TNF-alphaor IFN-gamma TRAIL was induced in...
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