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Oxaloacetate reduces emotional symptoms in premenstrual syndrome (PMS): results of a placebo-controlled, cross-over clinical trial

Tully L, Humiston J, Cash A

OBJECTIVE: Premenstrual syndrome (PMS) affects millions of women. While over-the-counter products have helped with the physical symptoms of PMS, emotional symptoms have been less well supported. The objective of this...
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Factorial Validity of the Korean Version of the Illness Intrusive Rating Scale among Psychiatric Outpatients Mainly Diagnosed with Anxiety or Depressive Disorders

Cho Y, Kim D, Kim E, Jo HY, Yun M, Lee H

OBJECTIVES: The Illness Intrusiveness Rating Scale (IIRS) is a well-validated self-report instrument for assessing negative impact of chronic illness and/or adverse effects of its treatment on everyday life domains. Although...
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Analysis of State-Trait Anxiety Inventory for Patients Diagnosed with Insomnia in an Outpatient Department

Lee SD, Ryu SH, Ha JH, Jeon HJ, Park DH

OBJECTIVES: Insomnia patients who visited the psychiatric outpatient of a university department, were divided into those patients with insomnia alone and those with depression or anxiety disorder, along with insomnia....
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The Psychometric Properties of the Patient Health Questionnaire-9 in a Sample of Korean University Students

Kim YE, Lee B

OBJECTIVE: Depressive symptoms among university students are a major mental-health issue worldwide, and university students are particularly vulnerable to various stressors that can produce depression. Therefore, accurate and sustainable assessment...
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Neuropsychiatric Symptoms of Multiple Sclerosis: State of the Art

Silveira C, Guedes R, Maia D, Curral R, Coelho R

Multiple Sclerosis (MS) is a chronic disabling neuroinflammatory disease. Psychiatric manifestations have a high prevalence in MS patients and may worsen the illness progression and the patients’ quality of life...
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The Association of Childhood Experience of Peer Bullying with DSM-IV Psychiatric Disorders and Suicidality in Adults: Results from a Nationwide Survey in Korea

Woo J, Chang SM, Hong JP, Lee DW, Hahm BJ, Cho SJ, Park JI, Jeon HJ, Seong SJ, Park JE, Kim BS

BACKGROUND: Few studies have examined the association between childhood bullying and adulthood mental disorders based on the Diagnostic and Statistical Manual of Mental Disorders (DSM) criteria. We investigated the association...
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Comparison of Vitex agnus-castus Extracts with Placebo in Reducing Menopausal Symptoms: A Randomized Double-Blind Study

Naseri R, Farnia V, Yazdchi K, Alikhani M, Basanj B, Salemi S

BACKGROUND: Menopausal symptoms have remarkable negative effects on women's quality of life, justifying the need to assess various therapeutic options. This research aimed to determine the effectiveness of Vitex agnus-castus...
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Burden of Psychiatric Disorders among Pediatric and Young Adults with Inflammatory Bowel Disease: A Population-Based Analysis

Thavamani , Umapathi K, Khatana J, Gulati R

PURPOSE: There is increasing prevalence of psychiatric disorders among inflammatory bowel Disease (IBD) population. Further, presence of psychiatric disorders has been shown as an independent predictor of quality of life...
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Selective serotonin reuptake inhibitor escitalopram inhibits 5-HT₃ receptor currents in NCB-20 cells

Park YS, Sung KW

Escitalopram is one of selective serotonin reuptake inhibitor antidepressants. As an S-enantiomer of citalopram, it shows better therapeutic outcome in depression and anxiety disorder treatment because it has higher selectivity...
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Associations of Ubiquitin-Specific Protease Genes with Resilience and Social Anxiety in Healthy Youths

Seo JH, Park CI, Kim SJ, Kang JI

OBJECTIVE: Dynamic proteolysis, through the ubiquitin-proteasome system, is an important molecular mechanism for the constant regulation of synaptic plasticity and stress responses in humans. In this study, we examined whether...
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Relationship between Negative Sexual Experience and Psychiatric Symptoms in Patients with Depression or Anxiety Disorders by Gender and Type of Negative Sexual Experience

Ji MA, Jeong BR, Chae JH

OBJECTIVE: This study aims to investigate the relationship between negative sexual experience and psychiatric symptoms by gender and compare the effects of sexual assault and unwanted sexual experiences on psychiatric...
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Diagnostic Issues of Depressive Disorders from Kraepelinian Dualism to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition

Park SC, Kim YK

Because the Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM-IV) was mainly influenced by the neo-Kraepelinian approach, its categorical approach to defining mental disorders has been criticized from...
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Gastro Oesophageal Reflux Disease Shadowing Anxiety Disorder Causing Prolonged Exposure to Proton Pump Inhibitor

Tahir NS, Zakaria R, Draman N

Anxiety disorders are the most prevalent psychiatric disorders in the general population. The relationship between dyspepsia and particularly gastroesophageal reflux disease (GERD) and psychiatric comorbidity such as anxiety is poorly...
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Reliability and Validity of the Korean Version of Clinician-Administered Posttraumatic Stress Disorder Scale for DSM-5

Kim WH, Jung YE, Roh D, Kim D, Kang SH, Chae JH, Park JE

BACKGROUND: For diagnosis of post-traumatic stress disorder (PTSD), the Clinician-Administered PTSD Scale (CAPS) is one of the most widely used structured diagnostic interviews. METHODS: In this study, we aimed to develop...
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Anxiety Sensitivity and Quality of Life in Patients with Acne

Acer E, Altınoz A, Erdogan HK, Agaoglu E, Yuksel Canakcı N, Saracoglu

BACKGROUND: Anxiety sensitivity (AS) is a continuous fundamental fear and defined as extreme fear of anxiety sensations and symptoms. High AS can cause tendency to anxiety disorders. There are many...
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Clinical Aspects of Premonitory Urges in Patients with Tourette's Disorder

Nam SH, Park J, Park TW

Most patients with Tourette's disorder experience an uncomfortable sensory phenomenon called the premonitory urge immediately before experiencing tics. It has been suggested that premonitory urges are associated with comorbidities such...
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Comparison of Effectiveness of Psychotherapies for Relieving Depressive Symptoms in Anxiety Disorders: A Systematic Review

Kim SY, Kim EJ, Jeon SW, Shin DW, Shin YC, Oh KS

OBJECTIVE: The purpose of this study was to compare and analyze effectiveness of various psychotherapies of depressive symptoms in patients with anxiety disorders by means of a systemic review. METHODS: A...
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Risks of Completed Suicide of Community Individuals with ICD-10 Disorders Across Age Groups: A Nationwide Population-Based Nested Case-Control Study in South Korea

Na EJ, Lee H, Myung W, Fava M, Mischoulon D, Paik JW, Hong JP, Choi KW, Kim H, Jeon HJ

OBJECTIVE: Suicide is the leading cause of death in 10–39-year-olds in South Korea, and the second highest rate among the OECD countries. However, few studies have investigated the particularity of...
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Psychiatric Symptoms in Systemic Lupus Erythematosus: Diagnosis and Treatment

Yoon S, Kang DH, Choi TY

According to the American College of Rheumatology classification, lupus erythematosus has five psychiatric manifestations, including cognitive dysfunction, mood disorder, anxiety disorder, psychosis, and acute confusional state, which are frequently accompanied...
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Pharmacological Therapy in Panic Disorder: Current Guidelines and Novel Drugs Discovery for Treatment-resistant Patient

Zulfarina , Syarifah-Noratiqah SB, Nazrun SA, Sharif R, Naina-Mohamed I

Panic disorder (PD) being one of the most intensively investigated anxiety disorders is considered a heterogeneous psychiatric disease which has difficulties with early diagnosis. The disorder is recurrent and usually...
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