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Curcumin-Induced Autophagy Augments Its Antitumor Effect against A172 Human Glioblastoma Cells

Lee JE, Yoon SS, Moon EY

Glioblastoma is the most aggressive common brain tumor in adults. Curcumin, from Curcuma longa, is an effective antitumor agent. Although the same proteins control both autophagy and cell death, the...
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Antimicrobial and Antitumor Photodynamic Effects of Phleichrome from the Phytopathogenic Fungus Cladosporium Phlei

So KK, Chun J, Kim DH

Fungal perylenequinones have photodynamic activity and are promising photosensitizers for photodynamic therapy (PDT). Here, we investigated the bactericidal and antitumor activities of phleichrome from the fungal perylenequinone family in vitro....
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Induction of Potent Antigen-specific Cytotoxic T Cell Response by PLGA-nanoparticles Containing Antigen and TLR Agonist

Lee YR, Lee YH, Kim KH, Im SA, Lee CK

Previously we showed that biodegradable nanoparticles containing poly-IC or CpG oligodeoxynucleotide (ODN) together with ovalbumin (OVA) were efficient at inducing MHC-restricted presentation of OVA peptides in dendritic cells. The CTL-inducing...
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alpha-Mangostin Reduced ER Stress-mediated Tumor Growth through Autophagy Activation

Kim SJ, Hong EH, Lee BR, Park MH, Kim JW, Pyun AR, Kim YJ, Chang SY, Chin YW, Ko HJ

alpha-Mangostin is a xanthon derivative contained in the fruit hull of mangosteen (Garcinia mangostana L.), and the administration of alpha-Mangostin inhibited the growth of transplanted colon cancer, Her/CT26 cells which...
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The Anti-tumor Activity of Vitamin C via the Increase of Fas (CD95) and MHC I Expression on Human Stomach Cancer Cell Line, SNU1

Yu Y, Bae S, Kim H, Kim Y, Chu NB, Chu NK, Kang JS, Lee WJ

BACKGROUND: It is already known that high concentration of vitamin C induces apoptosis on tumor cells. However, there is no report regarding the function of vitamin C on the modulation...
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Anti-cancer Activities of Ginseng Extract Fermented with Phellinus linteus

Lee JJ, Kwon HK, Jung IH, Cho YB, Kim KJ, Kim JL

In the present study, the anti-cancer effects of ginseng fermented with Phellinus linteus (GFPL) extract were examined through in vitro and in vivo assays. GFPL was produced by co-cultivating ginseng...
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Effect of Various Sawdusts and Logs Media on the Fruiting Body Formation of Phellinus gilvus

Jo WS, Rew YH, Choi SG, Hwang MH, Park SC, Seo GS, Sung JM, Uhm JY

  • KMID: 2312504
  • Mycobiology.
  • 2007 Mar;35(1):6-10.
Present experiments were conducted to determine the possibility of artificial culture with various sawdust of P. gilvus. The pH value was 6.0 of oak sawdust, 6.5 of mulberry sawdust, 6.6...
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Inhibitory Effect of Cordyceps Militaris Water Extracts on Sarcoma-180 Cell-Induced Ascities Tumor in ICR Mice

Lee H, Yang M, Park T

  • KMID: 2269709
  • Korean J Nutr.
  • 2003 Dec;36(10):1022-1029.
This study was undertaken to evaluate the antitumor activities of Cordyceps militaris of silkworm pupa (CMP) and silkworm larva (CML), as compared with the effect of cordycepin, an active compound...
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Liposomes as Acitivators of Lipophilic Platinum (2 ) Complexes

Han IS, Lee YJ

  • KMID: 2175291
  • J Korean Cancer Assoc.
  • 1999 Feb;31(1):180-187.
PURPOSE: The goal of this study is to understand the activation processes that take place within the liposomal formulation of lipophilic diaminocyclohexane platinum (DACH-Pt) complexes, to identify the activated species...
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In vitro cytotoxicity of novel platinum(II) coordination complexes containing diaminocyclohexane and diphenylphosphines

Jung JC, Kim YK, Park SJ, Chung JH, Chang SG, Lee KT, Baek MS, Park JJ, Rho YS

  • KMID: 1849848
  • Korean J Physiol Pharmacol.
  • 1998 Jun;2(3):395-401.
We have synthesized new platinum(H) analogs containing 1,2-diaminocyclohexane (dach) as a carrier ligand, 1,3-bis(diphenylphosphino) propane (DPPP) /1,2-bis(diphenylphosphino)ethane (DPPE) as a leaving group and nitrates to improve solubility. In the present study, the cytotoxicity of (Pt(trans-l-dach)(DPPP))cntdot2NO3...
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Antitumor activity of five new platinum complexes having a glycolate leaving ligand

Hong WS, Min YI, Kim HT, Cho YB, Kim KH, Kim DK

In an attempt to develop a new anticancer platinum complex with greater or equivalent antitumor activity but reduced side effects compared with cisplatin (CDDP), a series of new platinum complexes...
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