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Efficacy of Androgen Deprivation Therapy in Patients with Metastatic Castration-Resistant Prostate Cancer Receiving Docetaxel-Based Chemotherapy

Min K, Chung JW, Ha YS, Lee JN, Kim BS, Kim HT, Kim TH, Yoo ES, Kwon TG, Chung SK, Tanaka M, Egawa S, Kimura T, Choi SH

PURPOSE: The purpose of this study was to determine the comparative effectiveness of androgen deprivation therapy (ADT) combined with docetaxel (DTX)-based chemotherapy in Korean and Japanese castration-resistant prostate cancer (CRPC)...
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The Use of Gonadotropin-Releasing Hormone Agonist Does Not Affect the Development of Cardiovascular Disease in Prostate Cancer Patients: a Nationwide Population-Based Cohort Study

Shim M, Bang WJ, Oh CY, Lee YS, Jeon SS, Ahn H, Ju YS, Cho JS

BACKGROUND: The objective of this study was to investigate whether androgen deprivation therapy (ADT) with gonadotropin-releasing hormone agonist (GnRHa) in prostate cancer (Pca) patients is associated with cardiovascular disease in...
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Analysis of individual case safety reports of drug-induced anaphylaxis to the Korea Adverse Event Reporting System

Cho MK, Moon M, Kim HH, Kang DY, Lee JY, Cho SH, Kang HR

PURPOSE: To identify causative agents of the drug-induced anaphylaxis (DIA) by using the Korea Institute of Drug Safety & Risk Management-Korea Adverse Event Reporting System (KIDS-KAERS) database (Ministry of Food...
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Antitumor profiles and cardiac electrophysiological effects of aurora kinase inhibitor ZM447439

Lee HA, Kwon M, Kim HA, Kim KS

Aurora kinases inhibitors, including ZM447439 (ZM), which suppress cell division, have attracted a great deal of attention as potential novel anti-cancer drugs. Several recent studies have confirmed the anti-cancer effects...
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Effectiveness of three different luteinizing hormone-releasing hormone agonists in the chemical castration of patients with prostate cancer: Goserelin versus triptorelin versus leuprolide

Shim M, Bang WJ, Oh CY, Lee YS, Cho JS

PURPOSE: To investigate the changes in testosterone levels and rates of chemical castration following androgen-deprivation therapy (ADT) with goserelin, triptorelin, and leuprolide. MATERIALS AND METHODS: We retrospectively reviewed the medical records...
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Factors Influencing Compliance with Safety Guidelines of Anticancer Drugs Among Nurses in General Hospitals

Jung J, Park JY

PURPOSE: The purpose of this study was to investigate the level of compliance with the safety guidelines of anticancer drugs and identify the factors influencing compliance among general characteristics, knowledge...
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The Cancer Precision Medicine Diagnosis and Treatment (K-MASTER) Enterprise

Choi YJ, Kim YH

“Precision” trials, using reasonably integrated biomarker targets and molecularly selective anticancer agents, have become a major concern for both patients and their physicians. As next-generation sequencing, which is a parallel...
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The Treatments for Intermediate Risk Prostate Cancer

Shim M, Kwon T, Kim SC, Kim WS, Choo MS, Yeo JK

The population of intermediate-risk prostate cancer patients is a large heterogeneous group with diverse prognoses and challenges the struggle to develop more meticulous and standardized treatment recommendations. Furthermore, there are...
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Factors Influencing Distress in Premenopausal Patients with Breast Cancer Undergoing Endocrine Therapy

Kim J, Kang Y

PURPOSE: The purpose of this study was to investigate relationships among menopausal symptoms, functional status, and distress and to identify factors influencing distress in premenopausal breast cancer patients who had...
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Asian Society of Gynecologic Oncology International Workshop 2018

Kong TW, Ryu HS, Kim SC, Enomoto T, Li J, Kim KH, Shim SH, Wang PH, Therasakvichya S, Kobayashi , Lee M, Shi T, Lee SW, Mikami M, Nagase S, Lim MC, Wang J, Wilailak S, Kim SW, Hong SH, Tan DS, Mandai M, Chang SJ, Huang RY, Ushijima K, Lee JY, Chen X, Ochiai K, Lee TS, Yang B, Kalam F, Lv Q, Ahmad MF, Yaznil MR, Modi KB, Manopunya , Jeong DH, Lertkhachonsuk Aa, Chung HH, Watari H, Jeon S

The Asian Society of Gynecologic Oncology International Workshop 2018 on gynecologic oncology was held in the Ajou University Hospital, Suwon, Korea on the 24th to 25th August 2018. The workshop...
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Short-term Outcomes After Upfront Chemotherapy Followed by Curative Surgery in Metastatic Colon Cancer: A Comparison With Upfront Surgery Patients

Han MH, Park YY, Pratap S, Han YD, Cho MS, Hur H, Min BS, Lee KY, Kim NK

PURPOSE: Upfront systemic chemotherapy with target agents has been recommended for patients with stage IV colon cancer. Some with partial response are considered for curative resection. There is high risk...
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Status and Strategies for Safety Management of Antineoplastic Drugs among Oncology Nurses

Park JY, Noh GO, Kwon IG

PURPOSE: The purpose of this study was to identify the work environment related to the handling and administration of antineoplastic drugs in the members of the Korean Oncology Nursing Society. METHODS:...
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Cis-3-O-p-hydroxycinnamoyl Ursolic Acid Induced ROS-Dependent p53-Mediated Mitochondrial Apoptosis in Oral Cancer Cells

Wang CY, Lin CS, Hua CH, Jou YJ, Liao CR, Chang YS, Wan L, Huang SH, Hour MJ, Lin CW

Cis-3-O-p-hydroxycinnamoyl ursolic acid (HCUA), a triterpenoid compound, was purified from Elaeagnus oldhamii Maxim. This traditional medicinal plant has been used for treating rheumatoid arthritis and lung disorders as well as...
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Fertility preservation for adolescent and young adult cancer patients in Japan

Sugishita , Suzuki N

Adolescent and young adult (AYA) patients are generally defined as being from 15 to 39 years old. For preservation of fertility in AYA cancer patients, the best-known guideline in this...
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Histopathologic Study of Morbilliform Drug Eruption: Differences between Chemotherapeutic Agents and Antibiotics

Cho SY, Kwon JE, Han JH, Kim YC

  • KMID: 2436737
  • Korean J Dermatol.
  • 2018 Jul;56(6):368-375.
BACKGROUND: Cutaneous drug eruption is very common, and its clinical manifestations are variable. Diagnosis of drug eruption is usually based on clinical findings and medication history. To date, few studies...
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Clinical Analysis of Drug Eruptions among Inpatients Seeking a Consultation with the Department of Dermatology

Lee MY, Byun JY, Choi HY, Choi YW

  • KMID: 2436703
  • Korean J Dermatol.
  • 2018 Jun;56(5):314-321.
BACKGROUND: Drug eruptions are common in hospitalized patients. Rapid and accurate diagnosis is essential but often difficult. OBJECTIVE: This study defined the clinical features and causative drugs among inpatients presenting with...
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Cytotoxic Triterpenoids from the Fruits of Ligustrum japonicum

Ngo QM, Cao TQ, Woo MH, Min BS, Weon KY

Medicinal plants are potential sources of anticancer agents screening. A large number of phytochemicals, including triterpenoids, have been reported to have significant cytotoxic effects on cancer cells. From the fruits...
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Peptide Nucleic Acid Clamping and Direct Sequencing in the Detection of Oncogenic Alterations in Lung Cancer: Systematic Review and Meta-Analysis

Song JU, Lee J

PURPOSE: Molecular testing in non-small cell lung cancer (NSCLC) aids in identifying oncogenic alterations. The aim of this study was to compare the rates of detection of oncogenic alterations and...
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Efficacy of Pemetrexed-based Chemotherapy in Comparison to Non-Pemetrexed-based Chemotherapy in Advanced, ALK+ Non-Small Cell Lung Cancer

Jo J, Kim SH, Kim YJ, Lee J, Kim M, Keam B, Kim TM, Kim DW, Heo DS, Chung JH, Jeon YK, Lee JS

PURPOSE: Previous retrospective studies suggest that anaplastic lymphoma kinase (ALK) mutation-positive (ALK+) non-small cell lung cancer (NSCLC) patients are sensitive to pemetrexed. To determine its efficacy, we retrospectively evaluated clinical...
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Perception and Practice to Safely Manage Antineoplastic Agents among Parents of Children with Cancer

Kim YS, Park JY

PURPOSE: The purpose of this study was to investigate perception and practice for safety management of antineoplastic agents among parents of children with cancer. METHODS: The study used questionnaires of 131...
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