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Characterization of Chitinolytic and Antifungal Activities in Marine-Derived Trichoderma bissettii Strains

Chung D, Kwon YM, Lim JY, Bae SS, Choi G, Lee DS

Trichoderma fungi have been intensively studied for mycoparasitism, and the latter is closely related to their cell-wall degrading enzymes including chitinase. Here, we studied marinederived Trichoderma spp., isolated from distinct...
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Is It Cost Effective to Obtain Fungal and Acid-Fast Bacillus Cultures during Spine Debridement?

Lambrechts MJ, Clair DDS, Li J, Cook JL, Spence BS, Leary EV, Choma TJ, Moore DK, Goldstein CL

Study Design: Retrospective study. Purpose: To identify the rate of positive acid-fast bacillus (AFB) and fungal cultures during spine debridement, determine whether these infections are more common in certain spine segments,...
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Detection and Control of Candida auris in Healthcare Settings

Kwon YJ, Shin JH

Since it was first reported in 2009 after isolation from ear cultures of 1 Japanese patient and 15 Korean patients, Candida auris infections have been reported in at least 35...
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Prophylaxis for invasive fungal infection in pediatric patients with allogeneic hematopoietic stem cell transplantation

Perez P, Patiño J, Franco AA, Rosso F, Beltran E, Manzi E, Castro A, Estacio M, Valencia DM

Background Antifungal prophylaxis is recommended for hematopoietic stem cell transplantation (HSCT) to decrease the incidence of invasive fungal infections (IFI). This study aimed to compare the two groups of antifungal prophylaxis...
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Knockdown of vps54 aggravates tamoxifen-induced cytotoxicity in fission yeast

Lee S, Nam M, Lee AR, Baek ST, Kim MJ, Kim JS, Kong AH, Lee M, Lee SJ, Kim SY, Kim DU, Hoe KL

Tamoxifen (TAM) is an anticancer drug used to treat estrogen receptor (ER)‒positive breast cancer. However, its ER-independent cytotoxic and antifungal activities have prompted debates on its mechanism of action. To...
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Antifungal Activity of an Endophytic Fungus Aspergillus versicolor DYSJ3 from Aphanamixis grandifolia Blume against Colletotrichum musae

Li X, Wu Y, Liu Z

An endophytic fungus strain DYSJ3 was isolated from a stem of Aphanamixis grandifolia Blume, which was identified as Aspergillus versicolor based on the morphological characteristics, internal transcribed spacer (ITS) and...
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Evaluation of the early fluconazole treatment of candidemia protocol with automated short message service alerts: a before-and-after study

Yoo JR, Shin BR, Jo S, Heo ST

Background/Aims: We introduced the Early Fluconazole Treatment in Candidemia (EFTC) protocol in August 2015 to improve the outcomes of patients with candidemia. This study evaluated the effectiveness of the EFTC...
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Systematic Target Screening Revealed That Tif302 Could Be an OffTarget of the Antifungal Terbinafine in Fission Yeast

Lee S, Nam M, Lee AR, Lee J, Woo J, Kang NS, Balupuri A, Lee M, Kim SY, Ro H, Choi YW, Kim DU, Hoe KL

We used a heterozygous gene deletion library of fission yeasts comprising all essential and non-essential genes for a microarray screening of target genes of the antifungal terbinafine, which inhibits ergosterol...
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First Report: Diversity of Endophytic fungi Possessing Antifungal Activity Isolated from Native Kougoed (Sceletium tortuosum L.)

Sishuba A, Leboko J, Ateba CN, Manganyi MC

Forty-three (n = 43) endophytic fungi with different morphologic characteristics were from a medicinal plant Sceletium tortuosum, were utilized to investigate their antifungal effectiveness against pathogenic fungi. All fungal isolates exhibited antifungal...
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Screening of Endophytic Fungal Isolates Against Raffaelea quercus-mongolicae Causing Oak Wilt Disease in Korea

Nguyen MH, Yong JH, Sung HJ, Lee JK

Oak wilt disease caused by Raffaelea quercus-mongolicae has emerged obviously in Korea. We selected antifungal isolates against R. quercus-mongolicae among 368 endophytic fungal isolates from different parts of oak and...
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Characterization of Soil Microorganism from Humus and Indigenous Microorganism Amendments

Jan U, Feiwen R, Masood J, Chun SC

This study was conducted to understand the dynamics of microbial communities of soil microorganisms, and their distribution and abundance in the indigenous microorganisms (IMOs) manipulated from humus collected from the...
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Antifungal Susceptibility Tests and the cyp51 Mutant Strains among Clinical Aspergillus fumigatus Isolates from Korean Multicenters

Won EJ, Joo MY, Lee D, Kim MN, Park YJ, Kim SH, Shin MG, Shin JH

We investigated the antifungal susceptibilities and the cyp51 mutant strains among Aspergillus fumigatus clinical isolates obtained from 10 university hospitals in Korea. Of the 84 isolates examined, two itraconazole-resistant isolates...
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A Multicenter Study of Antifungal Use and Species Distribution and Antifungal Susceptibilities of Candida Isolates in South Korea

Shin JH, Won EJ, Kim SH, Shin JH, Lee D, Lee DH, Kim YA, Yi J, Shin JH, Shin KS, Jeong SH

Background: Candidiasis control should include monitoring the epidemiology and resistance to various antifungal agents. In this study, the researchers investigated the Candida species recovered from clinical specimens at particular geographic...
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Isolation, Screening, and Identification of Actinomycetes with Antifungaland Enzyme Activity Assays against Colletotrichum dematium ofSarcandra glabra

Song L, Jiang N, Wei S, Lan Z, Pan L

A serious leaf disease caused by Colletotrichum dematium was found during the cultivation of Sarcandra glabra in Jingxi, Rong’an, and Donglan Counties in Guangxi Province, which inflicted huge losses to plant productivity....
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Evaluation of Antifungal Activities of Bee Venom Components Against Malassezia Strains

Kim JH, Park J, Park KK, An HJ, Lee YW

BACKGROUND: Several studies about bee venom components have reported anti-fungal, anti-inflammatory, and anti-cancer effects. Malassezia species are components of skin flora, and also associated with many dermatologic diseases such as...
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Posaconazole versus Itraconazole as Prophylactic Antifungal Agents during Induction Chemotherapy for Acute Myeloid Leukemia: A Real-World Single Center Comparison

Kim C, Yoon SY, Lee MY, Kim KH, Lee N, Won JH

OBJECTIVE: To prevent invasive fungal disease (IFD) in acute myeloid leukemia (AML) patients, the use of posaconazole as a prophylactic antifungal agent has become standard in patients undergoing induction chemotherapy....
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Effect of Acaromyces Ingoldii Secondary Metabolites on the Growth of Brown-Rot (Gloeophyllum Trabeum) and White-Rot (Trametes Versicolor) Fungi

Olatinwo R, So CL, Eberhardt

We investigated the antifungal activities of an endophytic fungus identified as Acaromyces ingoldii, found on a loblolly (Pinus taeda L.) pine bolt in Louisiana during routine laboratory microbial isolations. The...
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Identification and Antifungal Susceptibility Profiles of Cyberlindnera fabianii in Korea

Park JH, Oh J, Sang H, Shrestha B, Lee H, Koo J, Cho SI, Choi JS, Lee MH, Kim J, Sung GH

Invasive fungal infections caused by Cyberlindnera fabianii have recently increased. However, biochemical kits such as API 20 C AUX and Vitek-2C have misidentified this species as other Candida spp. such...
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Usefulness of Treatment with Topical Antifungals in Burning Mouth Syndrome

Kim JH, Kim H, Jung KY, Baek SK

BACKGROUND AND OBJECTIVES: Burning mouth syndrome (BMS) is a poorly understood disease that is characterized by burning pain of the tongue without any identifiable organic disease. The pathophysiology of the...
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Antifungal effects of hydrogen water on the growth of Candida albicans

Park MJ, Choi YH, Song KB, Kim EK

OBJECTIVES: This study assessed the antifungal effects of neutral electrolysis hydrogen water, an agent known for its oral anti-bacterial effects on the growth of C. albicans in vitro. METHODS: Hydrogen water,...
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