- A Perspective: Role of Targeted Therapy in Colon Cancer
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Chung HH, Jang BI
- KMID: 1501635
- Korean J Gastroenterol.
- 2013 Mar;61(3):128-135.
- doi: 10.4166/kjg.2013.61.3.128
Colorectal cancer is the third most common malignant disease in incidence according to a report in 2009 from Korea. The 5-fluorouracil (5-FU) remains to be a major chemotherapeutic agents. But,... -
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- Current and Emerging Biologics for Ulcerative Colitis
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Park SC, Jeen YT
- KMID: 2380778
- Gut Liver.
- 2015 Jan;9(1):18-27.
- doi: 10.5009/gnl14226
Conventional medical treatment for ulcerative colitis can have limited efficacy or severe adverse reactions requiring additional treatment or colectomy. Hence, different biological agents that target specific immunological pathways are being... -
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- Pathogenesis and Treatment of Intestinal Behcet's Disease
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Lee CK, Kim HJ
- KMID: 782880
- Korean J Gastroenterol.
- 2007 Jul;50(1):3-8.
Intestinal Behcet's disease (BD) refers to colonic ulcerative lesions documented by objective measures in patients with BD. Although the causes of intestinal BD are unknown, genetic, environmental, and immunological factors... -
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- Angiographically Documented Macular Ischemia after Single Bevacizumab for Macular Edema Secondary to Central Retinal Vein Occlusion
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Lee KH, Kang EC, Koh HJ
- KMID: 2419132
- Yonsei Med J.
- 2017 May;58(3):676-678.
- doi: 10.3349/ymj.2017.58.3.676
This report describes a case of angiographically documented foveal avascular zone (FAZ) enlargement after a single intravitreal injection of bevacizumab for macular edema secondary to central retinal vein occlusion (CRVO).... -
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- Drug Survival Rates of Tumor Necrosis Factor Inhibitors in Patients with Rheumatoid Arthritis and Ankylosing Spondylitis
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Kang JH, Park DJ, Lee JW, Lee KE, Wen L, Kim TJ, Park YW, Lee SS
- KMID: 1794597
- J Korean Med Sci.
- 2014 Sep;29(9):1205-1211.
- doi: 10.3346/jkms.2014.29.9.1205
We investigated the compliance of Korean patients using tumor necrosis factor (TNF) inhibitors to treat rheumatoid arthritis (RA) and ankylosing spondylitis (AS), and identified potential predictors associated with treatment discontinuation.... -
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- Salvage Chemotherapy after Gemcitabine Failure in Patients with Advanced Pancreatic Cancer: Survival Benefit in Selected Patients
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Lee JL, Kim YT
- KMID: 783035
- Korean J Gastroenterol.
- 2008 Jul;52(1):59-63.
No abstract available. -
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- Patients with Arthritis Undergoing Surgery: How Should We Manage Tumour Necrosis Factor Blocking Agents Perioperatively?: A Systematic Literature Review
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Pieringer , Danninger , Tzaribachev N, Bohler N, Pohanka E, Herold M
- KMID: 1776947
- Yonsei Med J.
- 2013 Jan;54(1):253-257.
- doi: 10.3349/ymj.2013.54.1.253
We systematically reviewed the literature on the infectious risk in patients treated with tumour necrosis factor blocking agents (TNF-BA) undergoing surgery: we searched the Medline (PubMed) and the online archive... -
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- Second Line Chemotherapy for Pancreatic Cancer
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Park JY
- KMID: 1718400
- Korean J Gastroenterol.
- 2011 Apr;57(4):207-212.
- doi: 10.4166/kjg.2011.57.4.207
Pancreatic cancer is a very lethal cancer. It is the 5th most common cause for cancer related mortality in Korea. Most of patients have unresectable pancreatic cancer, and systemic chemotherapy... -
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- Eosinophilic Esophagitis
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Park H
- KMID: 782931
- Korean J Gastroenterol.
- 2007 Nov;50(5):286-291.
Eosinophilic esophagitis (EE) is characterized by eosinophilic infiltration of the esophageal wall including mucosa, submucosa, and muscle proper. EE is a condition involving both pediatrics and adults. Patients with EE... -
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- Diverse Molecular Targets for Therapeutic Strategies in Alzheimer's Disease
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Han SH, Mook-Jung
- KMID: 1789947
- J Korean Med Sci.
- 2014 Jul;29(7):893-902.
- doi: 10.3346/jkms.2014.29.7.893
Alzheimer's disease (AD) is the most common form of dementia caused by neurodegenerative process and is tightly related to amyloid beta (Abeta) and neurofibrillary tangles. The lack of early diagnostic... -
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- A Case of Crohn's Disease Showing Favorable Response to Induction and Maintenance Therapy with Methotrexate after Failure of Anti-tumor Necrosis Factor Therapy
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Choi J, Yun GW, Park YM, Kim JH, Youn YH, Park H, Park JJ
- KMID: 2373347
- Korean J Gastroenterol.
- 2015 Oct;66(4):231-236.
- doi: 10.4166/kjg.2015.66.4.231
Thanks to the introduction of immumomodulators and biologics, therapeutic approaches in Crohn's disease have changed significantly during the past decade. Although new biologic therapy has dramatically improved the treatment of... -
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- The Effect of Bortezomib on Antibody-Mediated Rejection after Kidney Transplantation
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Lee J, Kim BS, Park Y, Lee JG, Lim BJ, Jeong HJ, Kim YS, Huh KH
- KMID: 2345894
- Yonsei Med J.
- 2015 Nov;56(6):1638-1642.
- doi: 10.3349/ymj.2015.56.6.1638
PURPOSE: Recently, bortezomib has been used to treat antibody-mediated rejection (AMR) refractory to conventional treatment such as plasmapheresis, intravenous immunoglobulin, and rituximab. The authors aimed to describe their experiences when... -
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- Immune checkpoint blockade therapy for bladder cancer treatment
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Kim J
- KMID: 2426521
- Investig Clin Urol.
- 2016 Jun;57(Suppl 1):S98-S105.
- doi: 10.4111/icu.2016.57.S1.S98
Bladder cancer remains the most immunogenic and expensive malignant tumor in the United States today. As the 4th leading cause of death from cancer in United States, Immunotherapy blocking immune... -
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- Programmed death-1 pathway blockade produces a synergistic antitumor effect: combined application in ovarian cancer
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Zhu X, Lang J
- KMID: 2413224
- J Gynecol Oncol.
- 2017 Sep;28(5):e64.
- doi: 10.3802/jgo.2017.28.e64
Programmed death-1 (PD-1) and its ligand are part of the immune checkpoint pathway that down-regulates effector T cells in immune response, thereby causing immune suppression. The PD-1/programmed death-ligand 1 (PD-L1)... -
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- Changing Paradigm in the Management of Inflammatory Bowel Disease
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Jang BI
- KMID: 2373222
- Korean J Gastroenterol.
- 2015 May;65(5):268-272.
- doi: 10.4166/kjg.2015.65.5.268
Inflammatory bowel disease (IBD) is a chronic progressive idiopathic inflammatory disorder that involves the digestive tract from the mouth to the anus. Over the past decades, many therapeutic strategies have... -
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- Ideal Vaccination Strategy in Inflammatory Bowel Disease
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Lee CK
- KMID: 2373201
- Korean J Gastroenterol.
- 2015 Mar;65(3):159-164.
- doi: 10.4166/kjg.2015.65.3.159
Inflammatory bowel disease (IBD) is a long-standing disease that often requires long-term use of immunosuppressive agents including immunomodulators (such as azathioprine, 6-mercaptopurine and methotrexate) and tumor necrosis factor-alpha inhibitors (such... -
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- Therapeutic Experience of Bing-Neel Syndrome Associated with Waldenstrom's Macroglobulinemia
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Kim HD, Shin KC, Cho HS, Kim MK, Lee KH, Hyun MS
- KMID: 1785774
- J Korean Med Sci.
- 2007 Dec;22(6):1079-1081.
- doi: 10.3346/jkms.2007.22.6.1079
Waldenstrom's macroglobulinemia is an uncommon low-grade B-cell lymphoproliferative disorder in which monoclonal immunoglobulin M is produced. Neurological symptoms due to hyperviscosity are frequent manifestations of Waldenstrom's macroglobulinemia. However, central nervous... -
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- Recent developments in systemic chemotherapy for hepatocellular carcinoma
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Han CJ
- KMID: 1073325
- Korean J Hepatol.
- 2008 Mar;14(1):4-11.
- doi: 10.3350/kjhep.2008.14.1.4
Despite recent developments in various chemotherapeutic agents and the performing of numerous clinical trials, chemotherapy still produces unsatisfactory results in hepatocellular carcinoma due to poor clinical benefit compared with untreated... -
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- The Association between the Therapeutic Agent and the Compliance of the Patients with Inflammatory Bowel Diseases
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Kang YS, Kim SY, Jo MH, Kang HW, Lee JK, Lim YJ, Koh MS, Lee JH, Yang CH, Kim JH
- KMID: 1718062
- Korean J Gastroenterol.
- 2013 Jun;61(6):313-318.
- doi: 10.4166/kjg.2013.61.6.313
BACKGROUND/AIMS: Adherence of the patients with inflammatory bowel diseases is important to maintain the remission. However, the patients do not always keep their appointments for treatment. The aim of this... -
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- Immunosuppression status of liver transplant recipients with hepatitis C affects biopsy-proven acute rejection
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Kim JM, Lee KW, Song GW, Jung BH, Lee HW, Yi NJ, Kwon CD, Hwang S, Suh KS, Joh JW, Lee SK, Lee SG
- KMID: 2373137
- Clin Mol Hepatol.
- 2016 Sep;22(3):366-371.
- doi: 10.3350/cmh.2016.0022
BACKGROUND/AIMS: The relationship between patient survival and biopsy-proven acute rejection (BPAR) in liver transplant recipients with hepatitis C remains unclear. The aims of this study were to compare the characteristics... -
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