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SARS-CoV-2 Antibody Response to the BNT162b2 mRNA Vaccine in Persons with Past Natural Infection

Kang YM, Choe KW, Lee KD, Kim KN, Kim MJ, Lim J

There are still no agreed guidelines on the vaccination of coronavirus disease 2019 (COVID-19) for previously infected patients. Here, we present two seropositive healthcare workers (HCWs) working in an isolation...
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Kidney transplantation in highly sensitized recipients

Park Y, Ko EJ, Chung BH, Yang CW

In kidney transplantation (KT), overcoming donor shortage is particularly challenging in patients with preexisting donor-specific antibodies (DSAs) against human leukocyte antigen (HLA), called HLA-incompatible KT (HLAi KT), carrying the risk...
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Radiologic Approach for Pulmonary Vasculitis

Kim C, Kim YK, Han J

Vasculitis is a systemic disease, characterized by inflammation of the vascular wall. Although rare, it is sometimes life-threatening due to diffuse pulmonary hemorrhage or acute glomerulonephritis. Besides primary vasculitis, whose...
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Clinical Characteristics of Patients with Persistent Apogeotropic and Persistent Geotropic Direction-Changing Positional Nystagmus

Si L, Shen B, Li Y, Ling X, Li K, Yang X

Background and Purpose This study aimed to determine the clinical features, diagnosis, and treatment of patients with persistent geotropic (pG) and persistent apogeotropic (pAG) direction-changing positional nystagmus (DCPN). Methods This retrospective...
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Causes of Positive Pretransplant Crossmatches in the Absence of Donor-Specific Anti-Human Leukocyte Antigen Antibodies: A Single-Center Experience

Kang H, Yoo J, Lee SY, Oh EJ

Pretransplant crossmatch (XM) testing is widely used for detecting preformed donor-specific antibodies (DSAs) against human leukocyte antigen (HLA). However, in some cases, there is a positive XM result in the...
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Neutralizing Antibody Responses to SARS-CoV-2 in Korean Patients Who Have Recovered from COVID-19

Kim YJ, Bae JY, Bae S, Hwang S, Kwon KT, Chang HH, Lee WK, Cui C, Lee GE, Kim SW, Park MS

Purpose: Neutralizing antibodies (NAbs) have been considered effective in preventing and treating viral infections. However, until now, the duration and clinical implications of antibody-mediated nature immunity in Koreans have remained...
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Clinical Experience of Male Primary Choriocarcinoma at the Samsung Medical Center

Ji YS, Park SH

Purpose The objective of this study was to describe and analyze the clinicopathological features of primary choriocarcinoma (PCC) observed in male patients treated at the Samsung Medical Center between 1996 and...
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Current advances in pharmacological treatments for patients with COVID-19

Kim SB, Yeom JS

Since the coronavirus disease 2019 (COVID-19) outbreak, more than 150 million people in over 200 countries have been infected, with over 3 million people dying due to it, as of...
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Prevalence of autoantibodies that bind to kidney tissues in cats and association risk with antibodies to feline viral rhinotracheitis, calicivirus, and panleukopenia

Songaksorn N, Petsophonsakul W, Pringproa K, Lampang KN, Sthitmatee N, Srifawattana N, Piyarungsri K, Thongkorn K

Background: The feline viral rhinotracheitis, calicivirus, and panleukopenia (FVRCP) vaccine, prepared from viruses grown in the Crandell-Rees feline kidney cell line, can induce antibodies to cross-react with feline kidney tissues. Objectives:...
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Clinical Characteristics, Management, and Potential Biomarkers of Endocrine Dysfunction Induced by Immune Checkpoint Inhibitors

Iwama S, Kobayashi T, Arima H

Immune-related adverse events (irAEs) affecting the endocrine glands are among the most frequent irAEs induced by immune checkpoint inhibitors (ICIs) and include hypopituitarism, primary adrenal insufficiency, thyrotoxicosis, hypothyroidism, hypoparathyroidism, and...
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Clinical and serological prognostic markers in primary biliary cholangitis

Wilhelmi M

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Influence of Test Parameters on the Performance of Rapid Anti-Hepatitis C Virus Immunochromatographic Assay

Choi EJ, Kim JH, Han MS

Anti-hepatitis C virus (HCV) immunochromatographic assay (ICA) is commonly used as an early screening test for HCV infection. This study evaluated the influence of test parameters (technician, assay type, kit...
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Clinical significance of de novo donor-specific antibody in kidney transplant recipients with chronic antibody-mediated rejection

Park WY, Kim Y, Paek JH, Jin K, Han S

Background: Chronic antibody-mediated rejection (CABMR) is an important cause of late graft loss. De novo donor-specific antibody (dnDSA) is an important prognostic factor for long-term allograft outcomes. However, the prognosis...
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Comparison of Serologic Response of Hospitalized COVID-19 Patients Using 8 Immunoassays

Lee SM, Kim IS, Lim S, Lee SJ, Kim WJ, Shin KH, Moon SY, Chang CL

Background: In Korea, there were issues regarding the use of immunoassays for anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies to detect infection. So, we compared antibody results of eight...
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Clinical Evaluation of Five Commercial Serological SARS-CoV-2 Immunoassays for COVID-19

Shin W, Bang HI, Yu GY, Kim MY, Jang EY, Kim JA, Kim J, Park R, Shin JW, Choi TY

Background: Coronavirus disease 2019 (COVID-19) is a serious infectious disease caused by the highly contagious severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In this study, three types of kits for...
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Rapid Tests for the Diagnosis of Viral Infections

Kim HS

Rapid and accurate diagnostic tests for viral infections are essential for diagnosis, treatment, and patient isolation. Various rapid nucleic acid tests, rapid antigen tests, and rapid antibody tests have been...
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Prognostic Value of Serum Epstein-Barr Virus Antibodies and Their Correlation with TNM Classification in Patients with Locoregionally Advanced Nasopharyngeal Carcinoma

Zhang WR, Du YY, Guo CY, Zhou HX, Lin JY, Meng XH, Mo HY, Luo DH

Purpose This study assessed the correlation between Epstein-Barr virus (EBV) biomarkers and the eighth American Joint Committee on Cancer staging system and the prognostic values of IgG antibodies against replication...
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A case of pulmonary thromboembolism and splenic infarction in mycoplasma pneumonia

Kwon EW, Lee DW

Mycoplasma pneumoniae pneumonia is one of the most common causes of community-acquired pneumonia in school-aged pediatric patients. Its severity varies ranging from mild respiratory symptoms to severe complications with atypical...
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Management of Women with Antiphospholipid Antibodies or Antiphospholipid Syndrome during Pregnancy

Lee EE, Jun JK, Lee EB

Antiphospholipid syndrome (APS), which is characterized by the presence of antiphospholipid antibodies (aPL), is associated with increased risk of thrombosis and obstetric complications, including preterm delivery and recurrent pregnancy losses....
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Proprotein convertase subtilisin/kexin type 9 inhibition in cardiovascular disease: current status and future perspectives

Cho KH, Hong YJ

Proprotein convertase subtilisin/kexin type 9 (PCSK 9) targets the degradation of low-density lipoprotein (LDL) receptors; it has been proved that its inhibition improves cardiovascular outcomes in patients with established atherosclerotic...
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