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Influence of Temperature and Injection Speed of a 0.5% Bupivacaine Solution on the Distribution in a Spinal Canal Model Filledwith Human Cerebrospinal Fluid

Lee KY, Lee JS, Kim JY, Shin YS

BACKGROUND: The density of 0.5% bupivacaine solution at 37degreesC is known to be slightly hypobaric. However, its clinical character in spinal anesthesia appears to be nearly isobaric. We tried...
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Comparison between Epidural Analgesia and Combined Spinal-Epidural Analgesia for Labor and Delivery

Park HS, Yang SY, Yoon SH, Son SC

BACKGROUND: This study was designed to compare analgesic efficacy and side effects of intrathecal morphine and fentanyl with epidural bupivacaine. METHODS: Twenty nine healthy women, ASA physical status 1 or 2...
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Combination of Small Doses of Subarachnoid Bupivacaine/Fentanyl and Epidural Bupivacaine in Combined Spinal-Epidural Anesthesia for Cesarean Section

Choi DH, Choi HS, Ahn HJ

BACKGROUND: An intrathecal injection of a small-dose local anesthetic and an opioid using combined spinal-epidural anesthesia (CSEA) technique is a new trend in regional anesthesia for cesarean section. Prophylactic...
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Patterns of Nerve Conduction Blockade by Different Combinations of Lidocaine-bupivacaine Mixture

Cho SK, Leem JW, Leem HS, Han SM, Kong HS, Choi Y

BACKGROUND: A mixture of local anesthetics such as lidocaine and bupivacaine has frequently been used in clinical practice. The rationale behind this is to take advantage of lidocaine's rapid...
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The Preemptive Analgesic Effect of Bupivacaine Infiltration on Postoperative Pain after Inguinal Herniorrhaphy

Lee IH, Lee IO, Kong MH, Lee MK, Kim NS, Lim SH, Choi YS

BACKGROUND: Preemptive analgesia is an antinociceptive treatment that prevents the establishment of central sensitization, which amplifies the postoperative pain. In this study, we investigated the preemptive effect of local...
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The Effects of Midazolam and Droperidol Pretreatment on the Cardiac Toxicity of Bupivacaine in Rabbits

Kim YS, Kang YJ, Kim DW, In JH, Yang SY, Lim YG

BACKGROUND: Unintended intravenous injection of bupivacaine causes severe cardiovascular complication, which is known for its difficulty in resuscitation. This study was performed to evaluate the effects of pretreatment with...
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Patient Controlled Analgesia Using Surgical Wound Infusion

In JH, Kim DW, Seo SW

BACKGROUND: This study was undertaken to evaluate the analgesic effect of a self administered surgical wound infusion of local anesthetic alone compared to combination of local anesthetic and morphine or...
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The Effect of Intrathecal Midazolam on Bupivacaine Induced Spinal Anesthesia after Hemorrhoidectomy

Lee YM, Kim MH, Choi YJ, Choi SJ, Kim JA

BACKGROUND: Benzodiazepines acting on the GABA receptor complex in the spinal cord are known to induce antinociception. In the present study we aimed to evaluate the effect of intrathecal...
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The Effects of Insulin in Treating Bupivacaine-Induced Cardiac Depression

Cho HS, Lee KH, Lee S, Lee JJ, Shin BS

Backgroud: Bupivacaine blocks the sodium channels enhanced by hypokalemia. Bupivacaine also inhibits the transient outward K+ current (Ito). Insulin, in contrast, enhances Ito and induces hypokalemia. ...
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The Effects of Epidural "Top-up" on Spinal Block during Combined Spinal Epidural Anesthesia for Cesarean Section

Choi DH, Park NK, Kim JA, Sim WS

BACKGROUND: Epidural "top-up" has been known to enhance spinal anesthesia in combined spinal-epidural anesthesia. Saline and local anesthetics were reported to have a volume effect when infused as epidural...
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Comparison of Intrathecal Meperidine, Fentanyl, or Placebo Added to 0.5% Hyperbaric Bupivacaine for Cesarean Section

Choi JH, Kong MH, Lim SH, Lee MK

BACKGROUND: The addition of various opioids to 0.5% hyperbaric bupivacaine intrathecally seems to potentiate analgesic effects of bupivacaine and to prolong the duration of analgesia. We compared the effect...
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