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A Case of Male-Pseudohermaphroditism due to 17-beta-hydroxysteroid Dehydrogenase Deficiency with Multiple Osteoporosis

Bang SC, Ha JH, Kim JH, Kim SJ, Seung KR, Choi JH

  • KMID: 2075339
  • Korean J Obstet Gynecol.
  • 1997 Sep;40(9):2097-2104.
A 37-year-old woman was admitted for chief complaints about primary amenorrhea and multiple bone pains. She was raised phenotypically female but her chromosomal study was no-rmal male karyotype(46 XY). On...
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Relationships of Basal Level of Serum 17-Hydroxyprogesterone with that of Serum Androstenedione and Their Stimulated Responses to a Low Dose of ACTH in Young Adult Patients with Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency

Kang MJ, Kim SM, Lee YA, Shin CH, Yang SW

A single measurement of serum 17alpha-hydroxyprogesterone (17OHP) level can be unreliable because of its marked diurnal variation. We investigated the relationship of serum level of 17OHP with that of androstenedione...
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A Case of 17a-Hydroxylase Deficiency in 17-Year-Old Girl

Park KY, Park KL, Rhee JH

  • KMID: 2461610
  • J Korean Soc Endocrinol.
  • 1996 Mar;11(1):102-107.
The single enzyme P-450c17 hydroxylase catalyzes the 17a-hydroxylation of both pregnenolone and progesterone and the side-chain cleavage of 17a-hydroxypregnenolone and 17a-hydroxypro- gesterone to dehydroepiandrosterone and androstenedione. This enzyme is located...
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Effect of Leptin on the Steroidogenesis of Cultured Human Granulosa Cells

Kim SK, Cho DJ, Kim MS, Hwang KJ, Kwon HC

  • KMID: 2235709
  • Korean J Fertil Steril.
  • 2000 Mar;27(1):15-22.
OBJECTIVE: To elucidate the location of leptin and receptors of ovary specimens obtained from patients undergoing hysterectomy by immunohistochemical staining and to determine the effect of leptin on the steroidogenesis...
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Plasma Androgen Response to hCG Stimulation in Prepubertal Boys with Cryptorchidism and Hypospadias

Park YM, Park YH

  • KMID: 1912523
  • Korean J Urol.
  • 1987 Feb;28(1):91-96.
Cryptorchidism and hypospadias are the most common disorders of sexual differentiation in the male. Although the etiology of these disorders is obscure, they represent abnormalities in androgen dependent events that...
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Effects of Adrenal Androgen Levels on Bone Age Advancement in Prepubertal Children: Using the Ewha Birth and Growth Cohort Study

Kwon JH, Lee HA, Kim YJ, Lee H, Park EA, Cho SJ, Gwak HS, Ha E, Park H, Kim HS

Bone age (BA) advancement in prepubertal children may be associated with earlier onset of puberty and obesity. This study aimed to define the effects of adrenal androgen levels on the...
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Plasma sex steroid hormones and leptin levels in preeclampsia

Kim KH, Lee KS

  • KMID: 2141692
  • Korean J Obstet Gynecol.
  • 2006 May;49(5):1007-1016.
OBJECTIVE: The aim of this study was to measure maternal plasma androgens, estrogen and leptin levels and to assess the role of these hormones in the pathogenesis of preeclampsia. METHODS: The...
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Plasma Androgen and Estrogen Levels in the Third Trimester of Pregnancy in Peeclampsia

Choi GH, Jung IK, Jang SK, Lee DH, Kim KH, Na YJ, Lee KS

  • KMID: 1876158
  • Korean J Perinatol.
  • 2006 Mar;17(1):42-49.
OBJECTIVE: The aim of this study was to measure maternal plasma androgens and estrogen levels and to assess the role of these hormones in the pathogenesis of preeclampsia. ...
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Serum Insulin-like Growth Factors and their Binding Proteins in the Women With Polycystic Ovary

Roh JS, Yoo JB, Jo SH, Kim HS, Hwang YY

  • KMID: 2261935
  • Korean J Obstet Gynecol.
  • 2000 May;43(5):795-805.
OBJECTIVE: The involvement of IGF system in hyperandrogenism and abnormal follicular development is controversial. This study is to assess whether IGF system contribute to it in the women with polycystic ovary(PCO). METHODS:...
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Clinical use of Urinary Androgen Metabolites in Hyperprolactinemia

Kim KR, Lim SK, Song YD, Lee HC, Huh KB, Kim ES, Nam SY, Lee EJ, Jung BC, Choi BK, Shin JH

  • KMID: 1999289
  • J Korean Soc Endocrinol.
  • 1997 Sep;12(3):443-449.
BACKGROUND: Hyperprolactinemia has been linked with hyperandrogenism and hirsutism in some women. High plasma Dihydroandrosterone and DHA-S levels were reported in patients with hyperprolactinemia and a dissociation of adrenal androgen...
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Steroid Hormone Metabolism in Patients with Pelvic Organ Prolapse

Bai SW, Jung BH, Yoon BS, Kim EH, Chung BC, Park JH, Shin JS, Kim SK, Park KH

  • KMID: 2272342
  • Korean J Obstet Gynecol.
  • 2004 May;47(5):946-951.
OBJECTIVE: To identify 1) whether the endogenous steroid hormone metabolism in patients with pelvic organ prolapse was different from that of normal women, 2) the relationship between endogenous steroid hormone...
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Insulin Resistance in Normal Weight Women with Polycystic Ovary Syndrome

Byun EK, Lee HJ, Oh JY, Hong YS, Chung HW, Sung YA

  • KMID: 2008160
  • J Korean Diabetes Assoc.
  • 2004 Aug;28(4):315-323.
BACKGROUND: Insulin resistance is considered a regular component of polycystic ovary syndrome (PCOS). However, several studies have failed to confirm insulin resistance in non-obese women with PCOS. The aim of...
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Dried Blood Spot Multiplexed Steroid Profiling Using Liquid Chromatography Tandem Mass Spectrometry in Korean Neonates

Choi R, Park HD, Oh HJ, Lee K, Song J, Lee SY

BACKGROUND: Screening for congenital adrenal hyperplasia (CAH) using immunoassays for 17α-hydroxyprogesterone generates many false-positive results. We developed and validated a liquid chromatography-tandem mass spectrometry (LC-MS/MS) assay for simultaneous quantification of...
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Genotype of Steroid 21-Hydroxylase Gene and Clinical Characteristics in Patients with Congenital Adrenal Hyperplasia 21-Hydroxylase Deficiency

Ko JM, Choi JH, Kim GH, Yoo HW

  • KMID: 2321977
  • J Korean Soc Pediatr Endocrinol.
  • 2005 Jun;10(1):57-63.
PURPOSE: This study was undertaken to characterize clinical features of congenital adrenal hyperplasia (CAH) with steroid 21-hydroxylase deficiency, identify appropriate dose of hydrocortisone to normalize endocrine abnormalities, and correlate between...
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