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Additive Antinociception between Intrathecal Sildenafil and Morphine in the Rat Formalin Test

Yoon MH, Park KD, Lee HG, Kim WM, An TH, Kim YO, Huang LJ, Hua CJ

The possible characteristics of spinal interaction between sildenafil (phosphodiesterase 5 inhibitor) and morphine on formalin-induced nociception in rats was examined. Then the role of the opioid receptor in the effect...
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The Effects of Preemptive Analgesia of Morphine and Ketorolac on Postoperative Pain, Cortisol, O2 Saturation and Heart Rate

Seo YJ, Yoon H

PURPOSE: This study investigated the preemptive analgesic effects of Morphine and Ketorolac on postoperative pain, cortisol, O2 saturation and heart rate for the first 24 hr after abdominal surgery. METHODS:...
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Analgesic effect of caudal epidural ketamine in cattle

Lee I, Yoshiuchi , Yamagishi , Oboshi K, Ayukawa Y, Sasaki N, Yamada H

  • KMID: 1089607
  • J Vet Sci.
  • 2003 Dec;4(3):261-264.
This study was performed to clarify the analgesic effect of ketamine injected into the first intercoccygeal (Co1-Co2) epidural space in standing cattle. Five adult cows were randomly received 3 treatments...
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The Effects of Ketamine Preemptive Analgesia on Postoperative Pain in Patients undergoing a Hystrectomy

Kim HY, Yoon HS

  • KMID: 966300
  • J Korean Acad Nurs.
  • 2006 Feb;36(1):114-126.
PURPOSE: This study was performed to evaluate the pre-emptive analgesic effects of a small dose of intravenous ketamine on postoperative pain in patients undergoing a hysterectomy. METHOD: Sixty patients...
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Does Intravenous Ketamine Enhance Analgesia after Arthroscopic Shoulder Surgery with Ultrasound Guided Single-Injection Interscalene Block?: A Randomized, Prospective, Double-Blind Trial

Woo JH, Kim YJ, Baik HJ, Han JI, Chung RK

Ketamine has anti-inflammatory, analgesic and antihyperalgesic effect and prevents pain associated with wind-up. We investigated whether low doses of ketamine infusion during general anesthesia combined with single-shot interscalene nerve block...
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Grape seed proanthocyanidin extract ameliorates monosodium iodoacetate-induced osteoarthritis

Woo YJ, Joo YB, Jung YO, Ju JH, Cho ML, Oh HJ, Jhun JY, Park MK, Park JS, Kang CM, Sung MS, Park SH, Kim HY, Min JK

Osteoarthritis (OA) is an age-related joint disease that is characterized by degeneration of articular cartilage and chronic pain. Oxidative stress is considered one of the pathophysiological factors in the progression...
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