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Calcium-influx increases SOD1 aggregates via nitric oxide in cultured motor neurons

Kim HJ, Im W, Kim S, Kim SH, Sung JJ, Kim M, Lee KW

  • KMID: 1090960
  • Exp Mol Med.
  • 2007 Oct;39(5):574-582.
Familial amyotrophic lateral sclerosis (fALS) is caused by mutations in Cu/Zn-superoxide dismutase (SOD1), and SOD1 aggregation and calcium toxicity are involved in neuronal death. However, the effect of altered calcium...
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