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Subcutaneous Immunotherapy for Allergic Asthma in a Single Center of Korea: Efficacy, Safety, and Clinical Response Predictors

Lee JH, Kim SC, Choi H, Jung CG, Ban GY, Shin YS, Nahm DH, Park HS, Ye YM

Allergen-specific immunotherapy is the only causal treatment for allergic diseases. However, the efficacy of immunotherapy may vary around the world due to differences in climate, the nature of aero-allergens and...
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FDG-PET/CT Brain Findings in a Patient With Macrophagic Myofasciitis

Van Der Gucht A, Aoun-Sebaiti M, Kauv P, Guedj E, Aouizerate J, Verger A, Gherardi R, Bachoud-Levi AC, Authier FJ, Itti E

Brain Positron Emission Tomography/Computed Tomography with 18F-fluorodeoxyglucose (FDG PET/CT) was performed in a 44-year-old woman with marked cognitive impairment, diffuse myalgias, sensory, memory and visual disorders, and chronic fatigue, presenting...
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Principles and Application of Mouse Model of Allergic Rhinitis

Mo JH

Allergic rhinitis is a one of the most prevalent disease and its prevalence has been increasing these days. Many researchers have used the mouse models to study the mechanism of...
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Polyionic vaccine adjuvants: another look at aluminum salts and polyelectrolytes

Powell BS, Andrianov , Fusco PC

Adjuvants improve the adaptive immune response to a vaccine antigen by modulating innate immunity or facilitating transport and presentation. The selection of an appropriate adjuvant has become vital as new...
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Assessment of mOMV adjuvant efficacy in the pathogenic H1N1 influenza virus vaccine

Lee BJ, Kwon HI, Kim EH, Park SJ, Lee SH, Choi YK, Kim SH

PURPOSE: Since the pandemic (H1N1) 2009 virus has been a seasonal flu which still poses great human health concerns worldwide, vaccination would be considered as the most effective strategy to...
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Can Acid Pocket-targeting Alginate-antacid (Gaviscon Double Action) Relieve Upper Gastrointestinal Symptoms in Gastro-oesophageal Reflux Disease?

Kim SE, Park MI

No abstract available.
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Clinical statistics: five key statistical concepts for clinicians

Choi YG

  • KMID: 2328619
  • J Korean Assoc Oral Maxillofac Surg.
  • 2013 Oct;39(5):203-206.
Statistics is the science of data. As the foundation of scientific knowledge, data refers to evidentiary facts from the nature of reality by human action, observation, or experiment. Clinicians should...
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The Interplay between Autophagy and Aging

Pyo JO, Yoo SM, Jung YK

Numerous studies have established a link between autophagy and aging; however, the relationship has not been clearly defined. Aging is a very complex process caused by the accumulation of various...
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Cerebral Microbleeds: Their Associated Factors, Radiologic Findings, and Clinical Implications

Kim BJ, Lee SH

  • KMID: 2094554
  • J Stroke.
  • 2013 Sep;15(3):153-163.
Cerebral microbleeds (CMBs) are tiny, round dark-signal lesions that are most often detected on gradient-echo MR images. CMBs consist of extravasations of blood components through fragile microvascular walls characterized by...
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Current practice in hemodynamic monitoring and management in high-risk surgery patients: a national survey of Korean anesthesiologists

Kim SH, Kim MJ, Lee JH, Cho SH, Chae WS, Cannesson

BACKGROUND: Hemodynamic optimization improves postoperative outcomes in high-risk surgery patients. The monitoring of cardiac output (CO) and dynamic parameters of fluid responsiveness can guide hemodynamic optimization. We conducted a survey...
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The Effect of Obstructive Sleep Apnea on DNA Damage and Oxidative Stress

Kang IG, Jung JH, Kim ST

  • KMID: 2278472
  • Clin Exp Otorhinolaryngol.
  • 2013 Jun;6(2):68-72.
OBJECTIVES: Obstructive sleep apnea syndrome (OSAS) is associated with repeated hypoxia and re-oxygenation. This characteristic of OSAS may cause oxidative stress and DNA damage. However, the link of OSAS with...
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Chemokine Systems Link Obesity to Insulin Resistance

Ota T

Obesity is a state of chronic low-grade systemic inflammation. This chronic inflammation is deeply involved in insulin resistance, which is the underlying condition of type 2 diabetes and metabolic syndrome....
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Extra-Intestinal Manifestation of Helicobacter pylori Infection: Allergic Diseases Including Asthma, Atopy and Idiopathic Urticaria

Shin CM

  • KMID: 2142889
  • Korean J Med.
  • 2013 Jun;84(6):774-780.
Helicobacter pylori (H. pylori) infection is known to be negatively associated with allergic diseases including asthma in epidemiologic studies, mainly from the western countries. Bronchial asthma and allergic diseases are...
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Helicobacter pylori and Hematologic Diseases

Kim CG

  • KMID: 2142888
  • Korean J Med.
  • 2013 Jun;84(6):769-773.
Helicobacter pylori has been considered as the possible etiology in many extragastric disease. Hematologic diseases such as immune thrombocytopenic purpura (ITP) and iron-deficiency anemia have been proposed to associate with...
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Assessment of Gastritis Using Operative Link for Gastritis Assessment System

Jang SH, Kim KM

Gastritis is an inflammatory condition of the gastric mucosa induced by Helicobacter pylori infection, autoimmunity and chemical agents. Although Sydney system was devised for semiquantitative methods of gastritis, most physicians...
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Ovarian stimulation and liver dysfunction: Is a clinical relationship possible? A case of hepatic failure after repeated cycles of ovarian stimulation

Giugliano , Cagnazzo E, Pansini G, Vesce F, Marci R

Liver damage induced by ovarian stimulation has been demonstrated in some cases reported in the literature. However, there has never been a fruitful debate on this topic. The present manuscript...
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Alum Directly Modulates Murine B Lymphocytes to Produce IgG1 Isotype

Jin BR, Kim SJ, Lee JM, Kang SH, Han HJ, Jang YS, Seo GY, Kim PH

Aluminum hydroxide (alum) is the most widely used adjuvant in human vaccines. Nevertheless, it is virtually unknown whether alum acts on B cells. In the present study, we explored the...
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Apical foramen morphology according to the length of merged canal at the apex

Kim HH, Min JB, Hwang HK

OBJECTIVES: The aim of this study was to investigate the relationship between the apical foramen morphology and the length of merged canal at the apex in type II root canal...
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Interaction between Sleep-Disordered Breathing and Acute Ischemic Stroke

Ahn SH, Kim JH, Kim DU, Choo IS, Lee HJ, Kim HW

BACKGROUND AND PURPOSE: Sleep-disordered breathing (SDB) is suggested to be strongly associated with ischemic strokes. Risk factors, stroke subtypes, stroke lesion distribution, and the outcome of SDB in stroke patients...
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Effects of Problem-Based Learning by Learning Style in Medical Education

Chae SJ

  • KMID: 2306495
  • Korean J Med Educ.
  • 2012 Dec;24(4):347-351.
PURPOSE: Although problem-based learning (PBL) has been popularized in many colleges, few studies have analyzed the relationship between individual differences and PBL. The purpose of this study was to analyze...
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