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Safety and Utility of Rush Immunotherapy with Aqueous Allergen Extracts for Treatment of Respiratory Allergies

Lee JH, Choi JH, Jeong KB, Lee SJ, Lee MK, Lee WY, Yong SJ, Kim SH

Background: Generally, allergen immunotherapy must be administered for three to five years. Meanwhile, rush immunotherapy (RIT) shortens the required duration for the build-up phase, thereby improving the therapy's convenience compared...
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Clinical Efficacy of Allergen-Specific Immunotherapy from Patient and Physician Perspectives

Shin YS, Jung JW, Park JW, Choi JH, Kwon JW, Lee S, Kim JH, Lee SM, Ahn YM, Han MY, on behalf of the Allergen and Immunotherapy Work Group of the Korean Academy of Asthma, Allergy and Clinical Immunology (KAAACI)

PURPOSE: Allergen-specific immunotherapy (AIT) is the only curative treatment for allergic diseases, but a few allergic patients receive AIT. In this multicenter cross-sectional study, we aimed to explore patient and...
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Allergen standardization

Park JW, Jeong KY

Allergen immunotherapy (AIT) and diagnostic tests are based on well qualified allergen extracts, which are derived from biologic organisms. The allergenicity of the extracts is markedly affected by the climate,...
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Decreased CRTH2 Expression and Response to Allergen Re-stimulation on Innate Lymphoid Cells in Patients With Allergen-Specific Immunotherapy

Mitthamsiri W, Pradubpongsa P, Sangasapaviliya A, Boonpiyathad T

PURPOSE: Group 2 innate lymphoid cells (ILC2s) have been implicated in the pathogenesis of allergic disease. However, the effect of allergen-specific immunotherapy (AIT) on ILCs remains to be clarified. The...
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Changes in basophil activation during immunotherapy with house dust mite and mugwort in patients with allergic rhinitis

Kim SH, Kim SH, Chung SJ, Kim JH, Lee SY, Kim BK, Lim KW, Chang YS

BACKGROUND: The basophil activation test (BAT) is a promising tool for monitoring allergen-specific immunotherapy responses. OBJECTIVE: We aimed to investigate the changes in basophil activation in response to the inhalant allergens...
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Changes in skin reactivity and associated factors in patients sensitized to house dust mites after 1 year of allergen-specific immunotherapy

Son JY, Jung MH, Koh KW, Park EK, Heo JH, Choi GS, Kim HK

BACKGROUND: Allergen-specific immunotherapy (SIT) can significantly improve symptoms and reduce the need for symptomatic medication. OBJECTIVE: The aim of this study was to investigate changes in skin reactivity to house dust...
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Allergic conjunctivitis in Asia

Thong BY

Allergic conjunctivitis (AC), which may be acute or chronic, is associated with rhinitis in 30%–70% of affected individuals, hence the term allergic rhinoconjunctivitis (AR/C). Seasonal and perennial AC is generally...
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Effect on quality of life of the mixed house dust mite/weed pollen extract immunotherapy

Li L, Guan K

BACKGROUND: Although many patients with allergic rhinitis have symptoms due to sensitization to more than one kind of allergens, and mixed allergen extracts are widely used for immunotherapy, there are...
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Allergen-specific immunotherapy in pediatric allergic asthma

Yukselen A

Allergen-specific immunotherapy (AIT) is the only curative way that can change the immunologic response to allergens and thus can modify the natural progression of allergic diseases. There are some important...
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Allergen Immunotherapy: Past, Present, and Future

Jutel M, Kosowska A, Smolinska

Allergen-specific immunotherapy (AIT), although in clinical use for more than a century, is still the only causal treatment of allergic diseases. The safety and efficacy of AIT has been demonstrated...
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A Survey of the Prescription Patterns of Allergen Immunotherapy in Korea

Hur GY, Kim TB, Han MY, Nahm DH, Park JW, Allergen and Immunotherapy Work Group of the Korean Academy of Asthma, Allergy and Clinical Immunology (KAAACI)

PURPOSE: Allergen immunotherapy (AIT) has been used as a curative and specific treatment of allergic diseases. However, no data on the prescription patterns of AIT in Korea is available. Therefore,...
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Diagnosis and Management of Grain-Induced Asthma

Quirce S, Diaz-Perales A

Grain-induced asthma is a frequent occupational allergic disease mainly caused by inhalation of cereal flour or powder. The main professions affected are bakers, confectioners, pastry factory workers, millers, farmers, and...
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Changes of Serum Cytokines After the Long Term Immunotherapy with Japanese Hop Pollen Extracts

Ye YM, Lee SK, Kim SH, Nahm DH, Suh CH, Park HS

Japanese hop (Hop J) pollen has been considered as one of the major causative pollen allergens in the autumn season. We developed a new Hop J immunotherapy extract in collaboration...
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