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A study on the effect of JNJ-10397049 on proliferation and differentiation of neural precursor cells

Karami N, Azari H, Rahimi M, Aligholi H, Kalantari T

The orexin 2 receptor plays a central role in maintaining sleep and wakefulness. Recently, it has been shown that sleep and wakefulness orchestrate the proliferation and differentiation of oligodendrocytes. Here,...
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Ibrutinib reduces neutrophil infiltration, preserves neural tissue and enhances locomotor recovery in mouse contusion model of spinal cord injury

Torabi S, Anjamrooz SH, Zeraatpisheh Z, Aligholi H, Azari H

Following acute spinal cord injury (SCI), excessive recruitment of neutrophils can result in inflammation, neural tissue loss and exacerbation of neurological outcomes. Ibrutinib is a bruton’s tyrosine kinase inhibitor in...
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