- Paclitaxel-resistant cancer cell-derived secretomes elicit ABCB1-associated docetaxel cross-resistance and escape from apoptosis through FOXO3a-driven glycolytic regulation
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Aldonza MB, Hong JY, Lee SK
- KMID: 2367532
- Exp Mol Med.
- 2017 Jan;49(1):e286.
- doi: 10.1038/emm.2016.131
Chemotherapy-induced cancer cell secretomes promote resistance due, in part, to a predominant glycolytic energy metabolism, which drives aggressive cancer cell proliferation. However, the characterization of these secretomes and the molecular... -
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