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Update in the Mechanisms of Allergen-Specific Immunotheraphy

Akkoc T, Akdis M, Akdis CA

Allergic diseases represent a complex innate and adoptive immune response to natural environmental allergens with Th2-type T cells and allergen-specific IgE predominance. Allergen-specific immunotherapy is the most effective therapeutic approach...
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Mechanisms of immune tolerance to allergens in children

Kucuksezer UC, Ozdemir C, Akdis M, Akdis CA

Because the prevalence of allergic diseases has significantly increased in recent years, understanding the causes and mechanisms of these disorders is of high importance, and intense investigations are ongoing. Current...
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Role of Regulatory Cells in Oral Tolerance

Wawrzyniak M, O'Mahony L, Akdis M

The immune system is continuously exposed to great amounts of different antigens from both food and intestinal microbes. Immune tolerance to these antigens is very important for intestinal and systemic...
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