- Expression and Regulation of Osteoprotegerin in Adipose Tissue
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An JJ, Han DH, Kim DM, Kim SH, Rhee Y, Lee EJ, Lim SK
- KMID: 1122612
- Yonsei Med J.
- 2007 Oct;48(5):765-772.
- doi: 10.3349/ymj.2007.48.5.765
PURPOSE: Osteoprotegerin (OPG), a potent inhibitor of osteoclastic bone resorption, has a variety of biological functions that include anti-inflammatory effects. Adipocytes and osteoblasts share a common origin, and the... -
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- Implication of phosphorylation of the myosin II regulatory light chain in insulin-stimulated GLUT4 translocation in 3T3-F442A adipocytes
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Choi YO, Ryu HJ, Kim HR, Song YS, Kim C, Lee W, Choe H, Leem CH, Jang YJ
- KMID: 1111411
- Exp Mol Med.
- 2006 Apr;38(2):180-189.
In adipocytes, insulin stimulates glucose transport primarily by promoting the translocation of GLUT4 to the plasma membrane. Requirements for Ca2+/ calmodulin during insulin-stimulated GLUT4 translocation have been demonstrated; however, the... -
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- Inflammatory Gene Expression Patterns Revealed by DNA Microarray Analysis in TNF-alpha-treated SGBS Human Adipocytes
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Do MS, Jeong HS, Choi BH, Hunter L, Langley S, Pazmany L, Trayhurn P
- KMID: 1381255
- Yonsei Med J.
- 2006 Oct;47(5):729-736.
- doi: 10.3349/ymj.2006.47.5.729
We report here the use of human inflammation arrays to study the inflammatory gene expression profile of TNF-alpha- treated human SGBS adipocytes. Human preadipocytes (SGBS) were induced to differentiate in... -
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- Recent advance in brown adipose physiology and its therapeutic potential
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Lee YH, Jung YS, Choi D
- KMID: 2155343
- Exp Mol Med.
- 2014 Feb;46(2):e78.
- doi: 10.1038/emm.2013.163
Brown adipose tissue (BAT) is a specialized thermoregulatory organ that has a critical role in the regulation of energy metabolism. Specifically, energy expenditure can be enhanced by the activation of... -
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- B cell activation factor (BAFF) is a novel adipokine that links obesity and inflammation
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Kim YH, Choi BH, Cheon HG, Do MS
- KMID: 1123468
- Exp Mol Med.
- 2009 Mar;41(3):208-216.
- doi: 10.3858/emm.2009.41.3.024
B cell activation factor (BAFF) is a novel member of the TNF ligand superfamily, mainly produced by myeloid cells. BAFF has been shown to participate in B-cell survival and B-... -
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- Fenofibrate inhibits adipocyte hypertrophy and insulin resistance by activating adipose PPARalpha in high fat diet-induced obese mice
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Jeong S, Yoon M
- KMID: 756232
- Exp Mol Med.
- 2009 Jun;41(6):397-405.
- doi: 10.3858/emm.2009.41.6.045
Peroxisome proliferator-activated receptor alpha (PPARalpha) activation in rodents is thought to improve insulin sensitivity by decreasing ectopic lipids in non-adipose tissues. Fenofibrate, a lipid-modifying agent that acts as a PPARalpha... -
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- NF-kappaB is involved in the TNF-alpha induced inhibition of the differentiation of 3T3-L1 cells by reducing PPARg expression
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Chae GN, Kwak SJ
- KMID: 1093616
- Exp Mol Med.
- 2003 Oct;35(5):431-437.
TNF-alpha, a trimeric cytokine, was known to inhibit differention of preadipocytes to adipocytes. In the present study, we investigated signal mediators working downstream of TNF-alpha using murine 3T3-L1 cells. TNF-alpha... -
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- Association of anti-obesity activity of N-acetylcysteine with metallothionein-II down-regulation
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Kim JR, Ryu HH, Chung HJ, Lee JH, Kim SW, Kwun WH, Baek SH, Kim JH
- KMID: 1111409
- Exp Mol Med.
- 2006 Apr;38(2):162-172.
People with upper body or visceral obesity have a much higher risk of morbidity and mortality from obesity-related metabolic disorders than those with lower body obesity. In an attempt to... -
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- Transcriptional repression of type I procollagen genes during adipocyte differentiation
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Yi TG, Choi HM, Park RW, Sohn KY, Kim IS
- KMID: 1457541
- Exp Mol Med.
- 2001 Dec;33(4):269-275.
Adipocyte differentiation is a very complex process in which whole-cell changes are accompanied. Among them, type I procollagen gene has been shown to specifically decrease during adipocyte differentiation; however, little... -
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