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The adaptor protein LAD/TSAd mediates laminin-dependent T cell migration via association with the 67 kDa laminin binding protein

Park E, Choi Y, Ahn E, Park I, Yun Y

The adaptor protein, LAD/TSAd, plays essential roles in T cell activation. To further understand the functions of this protein, we performed yeast two-hybrid screening using TSAd as bait and identified...
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Negative feedback regulation of Wnt signaling by Gbetagamma-mediated reduction of Dishevelled

Jung H, Kim HJ, Lee SK, Kim R, Kopachik W, Han JK, Jho EH

Wnt signaling is known to be important for diverse embryonic and post-natal cellular events and be regulated by the proteins Dishevelled and Axin. Although Dishevelled is activated by Wnt and...
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Shank 2 expression coincides with neuronal differentiation in the developing retina

Kim JH, Kim JH, Yang E, Park JH, Yu YS, Kim KW

The retinal activity for vision requires a precise synaptic connectivity. Shank proteins at postsynaptic sites of excitatory synapses play roles in signal transmission into the postsynaptic neuron. However, the correlation...
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JNK/stress-activated protein kinase associated protein 1 is required for early development of telencephalic commissures in embryonic brains

Cho IH, Lee KW, Ha HY, Han PL

We previously reported that mice lacking JSAP1 (jsap1-/-) were lethal and the brain of jsap1-/- at E18.5 exhibited multiple types of developmental defects, which included impaired axon projection of the...
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