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Strategies for Renal Protection in Cardiovascular Interventions

Ali ZA, Escaned J, Dudek D, Radhakrishnan J, Galougahi KK

Coronary artery disease is highly prevalent in chronic kidney disease (CKD) and is a risk factor for contrast-associated acute kidney injury (CA-AKI), a complication of cardiovascular procedures that require contrast...
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Role of T cells in ischemic acute kidney injury and repair

Lee K, Jang HR

Ischemic acute kidney injury (AKI) is a common medical problem with significant mortality and morbidity, affecting a large number of patients globally. Ischemic AKI is associated with intrarenal inflammation as...
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Recalibration and validation of the Charlson Comorbidity Index in acute kidney injury patients underwent continuous renal replacement therapy

Lee J, Jung J, Lee J, Park JT, Jung CY, Kim YC, Kim DK, Lee JP, Shin SJ, Park JY

Background: Comorbid conditions impact the survival of patients with severe acute kidney injury (AKI) who require continuous renal replacement therapy (CRRT). The weights assigned to comorbidities in predicting survival vary...
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Estimating baseline creatinine values to define acute kidney injury in critically ill pediatric patients

Lee YJ, Park YS, Park SJ, Jhang WK

Background: Acute kidney injury (AKI) is a common complication in critically ill children. However, the common lack of baseline serum creatinine values affects AKI diagnosis and staging. Several approaches for...
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Role of bicarbonate and volume therapy in the prevention of acute kidney injury in rhabdomyolysis: a retrospective propensity score-matched cohort study

Kim HW, Kim S, Ohn JH, Kim NH, Lee J, Kim ES, Lim Y, Cho JH, Park HS, Ryu J, Kim Sw

Background: Although bicarbonate has traditionally been used to treat patients with rhabdomyolysis at high risk of acute kidney injury (AKI), it is unclear whether this is beneficial. This study compared...
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Olmesartan-associated Enteropathy with Acute Kidney Injury

Kang MJ, Min KH, Kim HW, Park SB, Kang DH, Choi CW, Kim SJ, Nam HS, Ryu DG

Olmesartan, a recently introduced angiotensin II receptor blocker for hypertension, has been reported to cause drug-induced small bowel enteropathy. The diagnosis of olmesartan-associated enteropathy (OAE) needs clinical suspicion and the...
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Additive harmful effects of acute kidney injury and acute heart failure on mortality in hospitalized patients

Son HE, Moon JJ, Park Jm, Ryu JY, Baek E, Jeong JC, Chin HJ, Na KY, Chae Dw, Han SS, Kim S

Background: Organ crosstalk between the kidney and the heart has been suggested. Acute kidney injury (AKI) and acute heart failure (AHF) are well-known independent risk factors for mortality in hospitalized...
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Alleviation of renal ischemia/reperfusion injury by exosomes from induced pluripotent stem cell-derived mesenchymal stem cells

Lim SW, Kim KW, Kim BM, Shin YJ, Luo K, Quan Y, Cui S, Ko EJ, Chung BH, Yang CW

Background/Aims: Renal ischemia followed by reperfusion (I/R) is a leading cause of acute kidney injury (AKI), which is closely associated with high morbidity and mortality. Studies have shown that induced...
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Current knowledge about biomarkers of acute kidney injury in liver cirrhosis

Lee HA, Seo YS

Acute kidney injury (AKI) is common in advanced cirrhosis. Prerenal azotemia, hepatorenal syndrome, and acute tubular necrosis are the main causes of AKI in patients with cirrhosis. Evaluation of renal...
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Probiotics partially attenuate the severity of acute kidney injury through an immunomodulatory effect

Yang J, Ji GE, Park MS, Seong YJ, Go YS, Lee HY, Fang Y, Kim MG, Oh SW, Cho WY, Jo SK

Background: A healthy microbiome helps maintain the gut barrier and mucosal immune tolerance. Previously, we demonstrated that acute kidney injury (AKI) provoked dysbiosis, gut inflammation, and increased permeability. Here, we...
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When and why to start continuous renal replacement therapy in critically ill patients with acute kidney injury

An JN, Kim SG, Song YR

Acute kidney injury (AKI) is a common condition in critically ill patients, and may contribute to significant medical, social, and economic consequences, including death. Although there have been advances in...
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Renal outcomes of laparoscopic versus open surgery in patients with rectal cancer: a propensity score analysis

Paek JH, Kang SI, Ryu J, Lim SY, Ryu JY, Son HE, Jeong JC, Chin HJ, Na KY, Chae DW, Kang SB, Kim S

Background: A laparoscopic approach is widely used in abdominal surgery. Although several studies have compared surgical and oncological outcomes between laparoscopic surgery (LS) and open surgery (OS) in rectal cancer...
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Hepatocyte growth factor and soluble cMet levels in plasma are prognostic biomarkers of mortality in patients with severe acute kidney injury

Li L, An JN, Lee J, Shin DJ, Zhu SM, Kim JH, Kim DK, Ryu DR, Kim S, Lee JP

Background: Hepatocyte growth factor (HGF)/cMet pathway is necessary for repair and regeneration following acute kidney injury (AKI). We evaluated the clinical potential of plasma HGF and soluble cMet as prognostic...
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Atypical Hemolytic Uremic Syndrome after Traumatic Rectal Injury: A Case Report

Kang JH, Lee D, Park Y

Atypical hemolytic uremic syndrome (aHUS) is a rare, progressive, life-threatening condition of thrombotic microangiopathy characterized by thrombocytopenia, microangiopathic hemolytic anemia, and renal impairment. The mechanisms underlying aHUS remain unclear. Herein,...
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Clinical outcomes and prognostic factors of mortality in liver cirrhosis patients on continuous renal replacement therapy in two tertiary hospitals in Korea

Jeon YH, Kim IY, Jang GS, Song SH, Seong EY, Lee DW, Lee SB, Kim HJ

Background: Data on liver cirrhosis (LC) patients undergoing continuous renal replacement therapy (CRRT) are lacking despite the dismal prognosis. We therefore evaluated clinical characteristics and predictive factors related to mortality...
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The Significance of the Strong Ion Gap in Predicting Acute Kidney Injury and In-hospital Mortality in Critically Ill Patients with Acute Poisoning

Sim TJ, Cho JW, Lee MJ, Jung H, Park J, Seo KS

Purpose: A high anion gap (AG) is known to be a significant risk factor for serious acid-base imbalances and death in acute poisoning cases. The strong ion difference (SID), or...
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COVID-19–induced acute kidney injury in critically ill patients: epidemiology, risk factors, and outcome

Trifi A, Abdellatif S, Masseoudi Y, Mehdi A, Benjima O, Seghir E, Cherif F, Touil Y, Jeribi B, Daly F, Abdennebi C, Ammous A, Lakhal SB

Background: The kidney represents a potential target for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Acute kidney injury (AKI) can occur through several mechanisms and includes intrinsic tissue injury by direct...
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Post-mortem assessment of vimentin expression as a biomarker for renal tubular regeneration following acute kidney injury

Moreno JCA, Bahmad HF, Febres-Aldana CA, Pirela A, Azuero A, Salami A, Poppiti R

Background: Acute kidney injury (AKI) is a common cause of morbidity and mortality. It mainly targets the renal tubular epithelium with pathological changes, referred to as acute tubular injury. The...
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Clinical Significance of Acute Kidney Injury in Lung Cancer Patients

Cho S, Kang E, Kim JE, Kang U, Kang HG, Park M, Kim K, Kim DK, Joo KW, Kim YS, Yoon HJ, Lee H

Purpose Acute kidney injury (AKI) in cancer patients is associated with increased morbidity and mortality. The incidence of AKI in lung cancer seems to be relatively higher compared with other solid...
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Poor Prognosis of Contrast-Induced Nephropathy during Long Term Follow Up

Liu T, Lee SR

Contrast-induced nephropathy (CIN) is known to associate with poor prognosis. However, there have been few studies for long-term follow up. The purpose of this study was to know the prognosis of...
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