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Aconitine Intoxication Misdiagnosed as Acute Myocardial Infarction

Ahn MS

A 55-year-old woman was admitted because of sudden onset of chest tightness after ingesting a herbal medicine. She experienced refractory ventricular arrhythmia after admission. Electrocardiography showed ST-segment abnormalities that mimicked...
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A Case of Aconite Poisoning Successfully Recovered after Intravenous Fat Emulsion Therapy

Shin HJ, Lim H

  • KMID: 2328241
  • J Korean Soc Clin Toxicol.
  • 2016 Jun;14(1):60-65.
Aconitum is a genus of various species of flowering plants that belongs to the Family Ranunculaceae. Most Aconitum sp. have extremely toxic alkaloid substances such as aconitine, mesaconitine and hypaconitine....
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A Case of Successful Resuscitation of 10,150 J Shocks and Therapeutic Hypothermia on Aconitine-induced Cardiovascular Collapse

Moon HJ, Lee JW, Kim KH, Jeong DK, Kim JH, Kim YK, Lee HJ

  • KMID: 2203556
  • J Korean Soc Clin Toxicol.
  • 2014 Dec;12(2):97-101.
Aconitine, found in the Aconitum species, is highly extremely toxic, and has been known to cause fatal cardiac arrhythmias and cardiovascular collapse. Although several reports have described treatment of aconitine...
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Analysis of QTc Prolongation Related to Arrhythmia in Patients with Aconitine Intoxication

Kim TK, Jin SC, Kim SJ, Choi WI

  • KMID: 2191965
  • J Korean Soc Emerg Med.
  • 2013 Oct;24(5):548-556.
PURPOSE: This study examined the association between the prolongation of heart rate-corrected QT (QTc) and arrhythmia in patients with aconitine intoxication. METHODS: A 13-year retrospective study of patients with aconitine poisoning...
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A Case of Severe Aconitine Intoxication with Ventricular Tachycardia, Successfully Treated by a Combination of Two Anti-arrhythmic Drugs

Ryoo SM, Sohn CH, Oh BJ, Kim W, Lim KS

  • KMID: 2101644
  • J Korean Soc Clin Toxicol.
  • 2011 Dec;9(2):105-108.
Aconitine is an anti-inflammatory agent with therapeutic uses in oriental medicine as an analgesic and for treatment of stroke. Because of its sodium channel effect, aconitine can promote undesirable, wide...
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Role of the Alternans of Action Potential Duration and Aconitine-Induced Arrhythmias in Isolated Rabbit Hearts

Jung BC, Lee SH, Cho YK, Park HS, Kim YN, Lee YS, Shin DG

Under conditions of Na+ channel hyperactivation with aconitine, the changes in action potential duration (APD) and the restitution characteristics have not been well defined in the context of aconitine-induced arrhythmogenesis....
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A Case of Aconitum Intoxication After Ingestion of a Large Amount of Aconitine Decoction in a Suicide Attempt

Kim YS, Cho JH, Park CW, Lee HY, Lee BK, Kim HJ, Park SM, Ahn MY

  • KMID: 1997760
  • J Korean Soc Emerg Med.
  • 2010 Oct;21(5):720-723.
Aconitine has been used as a folk remedy for centuries to treat pain and as an inotropic agent. However, because its therapeutic range is very narrow, it often causes many...
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The Toxicological Studies and Autopsy Findings of Aconitine Poisoning

Choi HK, Kim YS, Choi IS, Kim JH

  • KMID: 2305496
  • Korean J Leg Med.
  • 2010 May;34(1):15-19.
BACKGROUND: Aconitium species have been used for a material of oriental herb medicine for analgesic and anti-inflammatory effects. But Aconitium species were known to have the potent poisons like aconitine,...
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Toxicologic Features and Management in Aconitine Intoxication Following Ingestion of Herbal Tablets Containing Aconitum Species

Cho WL, Jin Y, Jeong TO, Lee JB, Kang JH

  • KMID: 2203439
  • J Korean Soc Clin Toxicol.
  • 2008 Dec;6(2):104-109.
PURPOSE: Unrefined tablets prepared from Aconitum tubers are occasionally used in Korean folk medicine. This study defines the potential sources, clinical toxicology, and treatment of aconitine poisoning. METHODS: A retrospective survey...
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An Outbreak of Caowu-intoxication after Drinking Home-brewed Alcohol

Kim SC, Ha YR, Kim YS, Kim HJ

  • KMID: 2332442
  • J Korean Soc Emerg Med.
  • 2008 Jun;19(3):339-345.
Caowu (aconite) is derived from the roots of certain aconitum species (Racunculaceae), which are widely distributed both in China and Korea. Aconitine, an extremely toxic ingredient present in aconite, has...
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Aconitine Intoxication Following Ingestion of Folk Recipes Containing Aconitum Species

Choi DI, Jin YH, Lee JB

  • KMID: 2194089
  • J Korean Soc Emerg Med.
  • 2002 Jun;13(2):175-180.
PURPOSE: Preparations of Aconitum roots in Chinese and Korean medicine are carefully prescribe for analgesic, antirheumatic and neurologic indications. However, in Korean folk medicine, a crude medical herb prepared from...
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Analysis of cardiovascular change of an Aconitum-containing Chinese Remedy

Mun JM, Lee BK, Chun BJ, Yoon HD, Heo T, Min YI

  • KMID: 1944455
  • J Korean Soc Emerg Med.
  • 2002 Mar;13(1):55-60.
PURPOSE: The roots of Aconitum plants (e.g.,A carmichaelii, A napellus) have been believed to possess antiinflammatory, analgesic, and cardiotonic effects and have been used in traditional Chinese medicine mainly for...
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Cardiovascular aspects of aconitine poisoning

Kim WS, Lim SS, Kang HS, Choue CW, Kim KS, Song JS, Bae JH

BACKGROUND AND OBJECTIVES: The Oriental herbal materials known as aconitine have long been used in oriental traditional medicine for their analgesic and antiinflammatory effects. Aconitine and its related alkaloids are...
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A case of aconitine poisoning with transient tetraplegia and hypocalcemia

Lim TH, Park KY

  • KMID: 1558499
  • Korean J Med.
  • 1998 Dec;55(6):1093-1096.
Both "caowu", the root of Aconitum kusnezoffii, "chuanwu", the main root of Aconitum carmichaeli are believed to possess anti-inflammatory, analgesics and cardiotonic effects. They have been used to treat conditions...
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The Changes of the Visual Evoked Potential for Aconitine Induced Visual Pathway Demyelination in Rabbit Model

Yoon KC, Kim SH

  • KMID: 1950025
  • J Korean Ophthalmol Soc.
  • 1992 Jun;33(6):622-626.
Aconitine, a principal constituent of aconite, may cause myelopathy on the visual pathway, spinal cord and peripheral nerve of the rabbits. A single dose of aconitine (O.6mg/kg), was administered intraperitoneally...
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Experimental Aconitine Optic Neuropathy

Kim SD, Kim SH

  • KMID: 2122962
  • J Korean Ophthalmol Soc.
  • 1990 May;31(5):661-679.
Effects of aconitine on the retina and optic nerve were studied in rabbits by means of visual evoked potential(VEP), electroretinogram(ERG), and electron microscopy. Aconitine(0.4mg/kg) was administered intra peritoneally. The effects...
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