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Aging impairs insulin-stimulated glucose uptake in rat skeletal muscle via suppressing AMPKalpha

Qiang W, Weiqiang K, Qing Z, Pengju Z, Yi L

  • KMID: 756077
  • Exp Mol Med.
  • 2007 Aug;39(4):535-543.
Insufficient intracellular fat oxidation is an important contributor to aging-related insulin resistance, while the precise mechanism underlying is unclear. AMP-activated protein kinase (AMPK) is an important regulator of intracellular fat...
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Role of 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside in the Growth Regulation of Anaplastic Thyroid Cancer Cells Lines

Song JY, Kim TY, Kim WB, Shong YK, Rhee YS, Suck JH, Hong SJ

BACKGROUND: Anaplastic thyroid carcinoma is one of the most aggressive human cancers with a median survival of only 6 months. Local surgical tumor debulking combined with radio-chemotherapy is generally used...
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