- Inhibitory Effects of Potassium Channel Blockers on Carbachol-induced Contraction in Rat Detrusor Muscle
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Oh SJ, Ahn SC
- KMID: 1130042
- J Korean Med Sci.
- 2003 Oct;18(5):701-706.
- doi: 10.3346/jkms.2003.18.5.701
We present accidental findings that potassium channel blockers, such as tetraethyl-ammonium (TEA) or 4-aminopyridine (4-AP), inhibit the sustained tonic contraction induced by carbachol in rat detrusor muscle strips. The relatively... -
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- 4-Aminopyridine (4-AP) augments Ca(2+)-dependent action potential and changes oscillatory firing patterns in rat cerebellar Purkinje cells
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Seo WS, Shin JH, Suh CK
- KMID: 711623
- Yonsei Med J.
- 1999 Apr;40(2):112-117.
- doi: 10.3349/ymj.1999.40.2.112
Intracellular recordings in cerebellar slice preparation showed that applications of 4-AP altered the pattern of oscillatory firing activity in Purkinje cells (PCs), especially yielding pronounced changes in action... -
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- Serotonin contracts the rat mesenteric artery by inhibiting 4-aminopyridine-sensitive Kv channels via the 5-HT2A receptor and Src tyrosine kinase
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Sung DJ, Noh HJ, Kim JG, Park SW, Kim B, Cho H, Bae YM
- KMID: 2154286
- Exp Mol Med.
- 2013 Dec;45(12):e67.
Serotonin (5-hydroxytryptamine (5-HT)) is a neurotransmitter that regulates a variety of functions in the nervous, gastrointestinal and cardiovascular systems. Despite such importance, 5-HT signaling pathways are not entirely clear. We... -
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