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Interleukin 1β Up-Regulates mRNA Expression of Inducible Nitric Oxide Synthase in 3T3-L1 Preadipocytes: Role of JAKs/STATs, PKCs, and Src

Park YK, Wang S, Jang BC

Recent evidence suggests obesity as a low or systemic chronic inflammation. (Pre)adipocytes in the adipose tissue (AT) express and secrete a variety of cytokines and adipokines. Inducible nitric oxide synthase...
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The protective effects of steamed ginger on adipogenesis in 3T3-L1 cells and adiposity in diet-induced obese mice

Kim B, Kim HJ, Cha YS

BACKGROUND/OBJECTIVES: The steamed ginger has been shown to have antioxidative effects and a protective effect against obesity. In the present study, we investigated the effects of ethanolic extract of steamed...
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Pear pomace water extract inhibits adipogenesis and induces apoptosis in 3T3-L1 adipocytes

Rhyu J, Kim MS, You MK, Bang MA, Kim HA

  • KMID: 2313708
  • Nutr Res Pract.
  • 2014 Feb;8(1):33-39.
Obesity occurs when a person's calorie intake exceeds the amount of energy burns, which may lead to pathologic growth of adipocytes and the accumulation of fat in the tissues. In...
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Arctiin inhibits adipogenesis in 3T3-L1 cells and decreases adiposity and body weight in mice fed a high-fat diet

Min B, Lee H, Song JH, Han MJ, Chung J

BACKGROUND/OBJECTIVES: The purpose of this study was to examine the effects and associated mechanisms of arctiin, a lignan compound found in burdock, on adipogenesis in 3T3-L1 cells. Also, the effects...
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Inhibitory effects of Capsicum annuum L. water extracts on lipoprotein lipase activity in 3T3-L1 cells

Baek J, Lee J, Kim K, Kim T, Kim D, Kim C, Tsutomu K, Ochir S, Lee K, Park CH, Lee YJ, Choe M

  • KMID: 2391960
  • Nutr Res Pract.
  • 2013 Apr;7(2):96-102.
Obesity, an intractable metabolic disease, currently has no medical treatment without side effects, so studies have been actively carried out to find natural compounds that have anti-obesity activity with minimum...
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The anti-obesity effect of Lethariella cladonioides in 3T3-L1 cells and obese mice

Sung JH, Chon JW, Lee MA, Park JK, Woo JT, Park YK

  • KMID: 2313557
  • Nutr Res Pract.
  • 2011 Dec;5(6):503-510.
The aim of this study was to investigate whether a water extract of L. cladonioides (LC) has an anti-obesity effect in 3T3-L1 cells and obese mice. Treatment of differentiated 3T3-L1...
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Transcriptome analysis and promoter sequence studies on early adipogenesis in 3T3-L1 cells

Kim SJ, Lee KH, Lee YS, Mun EG, Kwon DY, Cha YS

  • KMID: 2313288
  • Nutr Res Pract.
  • 2007 Mar;1(1):19-28.
To identify regulatory molecules which play key roles in the development of obesity, we investigated the transcriptional profiles in 3T3-L1 cells at early stage of differentiation and analyzed the promoter...
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